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Protein
Submitted name:

Apolipoprotein C-III

Gene

APOC3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Apolipoprotein C-IIIImported
Submitted name:
Apolipoprotein C-III variant 2Imported
Submitted name:
Apolipoprotein C-III variant 3Imported
Submitted name:
Apolipoprotein C-III, isoform CRA_aImported
Submitted name:
Apolipoprotein C3Imported
Gene namesi
Name:APOC3Imported
ORF Names:hCG_41334Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000110245.11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA53

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501429685821 – 99Sequence analysisAdd BLAST79

Keywords - PTMi

LipoproteinImported

Expressioni

Gene expression databases

BgeeiENSG00000110245

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410JE3N Eukaryota
ENOG4111APE LUCA
HOVERGENiHBG050549
KOiK08759

Family and domain databases

Gene3Di1.10.225.30, 1 hit
InterProiView protein in InterPro
IPR008403 Apo-CIII
IPR038195 Apo_CIII_sf
PANTHERiPTHR14225 PTHR14225, 1 hit
PfamiView protein in Pfam
PF05778 Apo-CIII, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD010414 Apo-CIII, 1 hit

Sequencei

Sequence statusi: Complete.

A3KPE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPRVLLVVA LLALLASARA SEAEDASLLS FMQGYMKHAT KTAKDALSSV
60 70 80 90
QESQVAQQAR GWVTDGFSSL KDYWSTVKDK FSEFWDLDPE VRPTSAVAA
Length:99
Mass (Da):10,852
Last modified:April 3, 2007 - v1
Checksum:iD4E806339FAE4DA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC134419 mRNA Translation: AAI34420.1
EF444950 Genomic DNA Translation: ACA05940.1
EF444950 Genomic DNA Translation: ACA05942.1
KJ437193 Genomic DNA Translation: AJA40867.1
CH471065 Genomic DNA Translation: EAW67272.1
CH471065 Genomic DNA Translation: EAW67273.1
RefSeqiNP_000031.1, NM_000040.1
UniGeneiHs.73849

Genome annotation databases

GeneIDi345
KEGGihsa:345

Similar proteinsi

Entry informationi

Entry nameiA3KPE2_HUMAN
AccessioniPrimary (citable) accession number: A3KPE2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: April 25, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health