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Protein
Submitted name:

Apolipoprotein C-III

Gene

APOC3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Apolipoprotein C-IIIImported
Submitted name:
Apolipoprotein C-III variant 2Imported
Submitted name:
Apolipoprotein C-III variant 3Imported
Submitted name:
Apolipoprotein C-III, isoform CRA_aImported
Submitted name:
Apolipoprotein C3Imported
Gene namesi
Name:APOC3Imported
ORF Names:hCG_41334Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA53.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 9979Sequence analysisPRO_5007634525Add
BLAST

Keywords - PTMi

LipoproteinImported

Expressioni

Gene expression databases

BgeeiENSG00000110245.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000227667.

Structurei

3D structure databases

SMRiA3KPE2. Positions 21-99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410JE3N. Eukaryota.
ENOG4111APE. LUCA.
HOVERGENiHBG050549.
KOiK08759.
PhylomeDBiA3KPE2.

Family and domain databases

InterProiIPR008403. Apo-CIII.
[Graphical view]
PANTHERiPTHR14225. PTHR14225. 1 hit.
PfamiPF05778. Apo-CIII. 1 hit.
[Graphical view]
ProDomiPD010414. Apo-CIII. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

A3KPE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPRVLLVVA LLALLASARA SEAEDASLLS FMQGYMKHAT KTAKDALSSV
60 70 80 90
QESQVAQQAR GWVTDGFSSL KDYWSTVKDK FSEFWDLDPE VRPTSAVAA
Length:99
Mass (Da):10,852
Last modified:April 3, 2007 - v1
Checksum:iD4E806339FAE4DA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC134419 mRNA. Translation: AAI34420.1.
EF444950 Genomic DNA. Translation: ACA05940.1.
EF444950 Genomic DNA. Translation: ACA05942.1.
KJ437193 Genomic DNA. Translation: AJA40867.1.
CH471065 Genomic DNA. Translation: EAW67272.1.
CH471065 Genomic DNA. Translation: EAW67273.1.
RefSeqiNP_000031.1. NM_000040.1.
UniGeneiHs.73849.

Genome annotation databases

GeneIDi345.
KEGGihsa:345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC134419 mRNA. Translation: AAI34420.1.
EF444950 Genomic DNA. Translation: ACA05940.1.
EF444950 Genomic DNA. Translation: ACA05942.1.
KJ437193 Genomic DNA. Translation: AJA40867.1.
CH471065 Genomic DNA. Translation: EAW67272.1.
CH471065 Genomic DNA. Translation: EAW67273.1.
RefSeqiNP_000031.1. NM_000040.1.
UniGeneiHs.73849.

3D structure databases

SMRiA3KPE2. Positions 21-99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000227667.

Protocols and materials databases

DNASUi345.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi345.
KEGGihsa:345.

Organism-specific databases

CTDi345.
PharmGKBiPA53.

Phylogenomic databases

eggNOGiENOG410JE3N. Eukaryota.
ENOG4111APE. LUCA.
HOVERGENiHBG050549.
KOiK08759.
PhylomeDBiA3KPE2.

Miscellaneous databases

GenomeRNAii345.

Gene expression databases

BgeeiENSG00000110245.

Family and domain databases

InterProiIPR008403. Apo-CIII.
[Graphical view]
PANTHERiPTHR14225. PTHR14225. 1 hit.
PfamiPF05778. Apo-CIII. 1 hit.
[Graphical view]
ProDomiPD010414. Apo-CIII. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiA3KPE2_HUMAN
AccessioniPrimary (citable) accession number: A3KPE2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: September 7, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.