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Protein
Submitted name:

Cacna1s protein

Gene

Cacna1s

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. high voltage-gated calcium channel activity Source: MGI
  2. voltage-gated calcium channel activity Source: MGI

GO - Biological processi

  1. calcium ion import Source: GO_Central
  2. calcium ion transport Source: MGI
  3. endoplasmic reticulum organization Source: MGI
  4. extraocular skeletal muscle development Source: MGI
  5. membrane depolarization during action potential Source: GO_Central
  6. muscle cell development Source: MGI
  7. muscle contraction Source: MGI
  8. myoblast fusion Source: MGI
  9. neuromuscular junction development Source: MGI
  10. skeletal muscle adaptation Source: MGI
  11. skeletal muscle fiber development Source: MGI
  12. skeletal muscle tissue development Source: MGI
  13. skeletal system development Source: MGI
  14. striated muscle contraction Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cacna1s proteinImported
Gene namesi
Name:Cacna1sImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88294. Cacna1s.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. I band Source: MGI
  3. plasma membrane Source: MGI
  4. sarcoplasmic reticulum Source: MGI
  5. T-tubule Source: MGI
  6. voltage-gated calcium channel complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriA3KPC9.

Structurei

3D structure databases

ProteinModelPortaliA3KPC9.
SMRiA3KPC9. Positions 3-150.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000231529.

Family and domain databases

InterProiIPR014873. VDCC_a1su_IQ.
IPR005450. VDCC_L_a1ssu.
[Graphical view]
PANTHERiPTHR10037:SF190. PTHR10037:SF190. 1 hit.
PfamiPF08763. Ca_chan_IQ. 1 hit.
[Graphical view]
SMARTiSM01062. Ca_chan_IQ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3KPC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPPSPQDEF KAIWAEYDPE AKGRIKHLDV VTLLRRIQPP LGFGKFCPHR
60 70 80 90 100
VACKRLVGMN MPLNSDGTVT FNATLFALVR TALKIKTEGN FEQANEELRA
110 120 130 140 150
IIKKIWKRTS MKLLDQVIPP IGDDEVTVGK FYATFLIQEH FRKFMKRQEE
160 170 180 190 200
YYGYRPKKDT VQIQAGLRTI EEEAAPEIHR AISGDLTAEE ELERAMVEAA
210 220 230 240 250
MEEGIFRRTG GLFGQVDNFL ERTNSLPPVM ANQRPLQFAE IEMEELESPV
260 270 280 290
FLEDFPQNPG THPLARANTN NANANVAYGN SSHRNNPVFS R
Length:291
Mass (Da):33,119
Last modified:April 3, 2007 - v1
Checksum:i681D7DAE084BBA27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC134369 mRNA. Translation: AAI34370.1.
UniGeneiMm.4418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC134369 mRNA. Translation: AAI34370.1.
UniGeneiMm.4418.

3D structure databases

ProteinModelPortaliA3KPC9.
SMRiA3KPC9. Positions 3-150.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:88294. Cacna1s.

Phylogenomic databases

HOGENOMiHOG000231529.

Miscellaneous databases

NextBioi35544715.
SOURCEiSearch...

Gene expression databases

GenevestigatoriA3KPC9.

Family and domain databases

InterProiIPR014873. VDCC_a1su_IQ.
IPR005450. VDCC_L_a1ssu.
[Graphical view]
PANTHERiPTHR10037:SF190. PTHR10037:SF190. 1 hit.
PfamiPF08763. Ca_chan_IQ. 1 hit.
[Graphical view]
SMARTiSM01062. Ca_chan_IQ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.

Entry informationi

Entry nameiA3KPC9_MOUSE
AccessioniPrimary (citable) accession number: A3KPC9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: March 4, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.