A3KN83 (SBNO1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein strawberry notch homolog 1

Alternative name(s):
Monocyte protein 3
Short name=MOP-3

Gene names

Name:	SBNO1
Synonyms:	MOP3

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1393 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities	Belongs to the SBNO family.
Sequence caution	The sequence AAQ76814.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Coiled coil
PTM	Acetylation Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: A3KN83-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: A3KN83-2)

The sequence of this isoform differs from the canonical sequence as follows:
     80-81: QQ → Q

Note: No experimental confirmation available.

Isoform 3 (identifier: A3KN83-3)

The sequence of this isoform differs from the canonical sequence as follows:
     78-79: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: A3KN83-4)

The sequence of this isoform differs from the canonical sequence as follows:
     80-81: QQ → Q
     722-733: VGGLTGSSSDDS → MSLMRMMKMIPG
     734-1393: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1393	1393	Protein strawberry notch homolog 1		PRO_0000314555
Regions
	Coiled coil	843 – 870	28	Potential
	Compositional bias	784 – 793	10	Poly-Lys
Amino acid modifications
	Modified residue	149	1	N6-acetyllysine Ref.8
	Modified residue	214	1	Phosphoserine Ref.6
	Modified residue	413	1	N6-acetyllysine Ref.8
	Modified residue	697	1	Phosphoserine Ref.5
	Modified residue	754	1	Phosphoserine Ref.9 Ref.11
	Modified residue	755	1	Phosphoserine Ref.9 Ref.11
	Modified residue	768	1	Phosphoserine By similarity
	Modified residue	794	1	Phosphoserine Ref.6 Ref.7 Ref.9
	Modified residue	815	1	Phosphoserine Ref.7
	Modified residue	1222	1	N6-acetyllysine Ref.8
Natural variations
	Alternative sequence	78 – 79	2	Missing in isoform 3.		VSP_030295
	Alternative sequence	80 – 81	2	QQ → Q in isoform 2 and isoform 4.		VSP_030296
	Alternative sequence	722 – 733	12	VGGLT…SSDDS → MSLMRMMKMIPG in isoform 4.		VSP_030297
	Alternative sequence	734 – 1393	660	Missing in isoform 4.		VSP_030298
	Natural variant	634	1	T → S in a breast cancer sample; somatic mutation. Ref.12		VAR_037910
	Natural variant	728	1	S → N. Corresponds to variant rs1060105 [ dbSNP | Ensembl ].		VAR_037911
	Natural variant	729	1	S → N. Corresponds to variant rs1060105 [ dbSNP | Ensembl ].		VAR_057794
	Natural variant	889	1	E → K in a breast cancer sample; somatic mutation. Ref.12		VAR_037912
	Natural variant	997	1	S → C in a breast cancer sample; somatic mutation. Ref.12		VAR_037913
Experimental info
	Sequence conflict	4	1	P → Q in AAQ76814. Ref.4
	Sequence conflict	14	1	S → R in BAA91842. Ref.3
	Sequence conflict	555	1	V → A in AAQ76814. Ref.4
	Sequence conflict	774	1	N → S in BAB19784. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: D2C42F29C7EEC20D	FASTA	1,393	154,312
	10 20 30 40 50 60 MVEPGQDLLL AALSESGISP NDLFDIDGGD AGLATPMPTP SVQQSVPLSA LELGLETEAA 70 80 90 100 110 120 VPVKQEPETV PTPALLNVRQ QPPSTTTFVL NQINHLPPLG STIVMTKTPP VTTNRQTITL 130 140 150 160 170 180 TKFIQTTAST RPSVSAPTVR NAMTSAPSKD QVQLKDLLKN NSLNELMKLK PPANIAQPVA 190 200 210 220 230 240 TAATDVSNGT VKKESSNKEG ARMWINDMKM RSFSPTMKVP VVKEDDEPEE EDEEEMGHAE 250 260 270 280 290 300 TYAEYMPIKL KIGLRHPDAV VETSSLSSVT PPDVWYKTSI SEETIDNGWL SALQLEAITY 310 320 330 340 350 360 AAQQHETFLP NGDRAGFLIG DGAGVGKGRT IAGIIYENYL LSRKRALWFS VSNDLKYDAE 370 380 390 400 410 420 RDLRDIGAKN ILVHSLNKFK YGKISSKHNG SVKKGVIFAT YSSLIGESQS GGKYKTRLKQ 430 440 450 460 470 480 LLHWCGDDFD GVIVFDECHK AKNLCPVGSS KPTKTGLAVL ELQNKLPKAR VVYASATGAS 490 500 510 520 530 540 EPRNMAYMNR LGIWGEGTPF REFSDFIQAV ERRGVGAMEI VAMDMKLRGM YIARQLSFTG 550 560 570 580 590 600 VTFKIEEVLL SQSYVKMYNK AVKLWVIARE RFQQAADLID AEQRMKKSMW GQFWSAHQRF 610 620 630 640 650 660 FKYLCIASKV KRVVQLAREE IKNGKCVVIG LQSTGEARTL EALEEGGGEL NDFVSTAKGV 670 680 690 700 710 720 LQSLIEKHFP APDRKKLYSL LGIDLTAPSN NSSPRDSPCK ENKIKKRKGE EITREAKKAR 730 740 750 760 770 780 KVGGLTGSSS DDSGSESDAS DNEESDYESS KNMSSGDDDD FNPFLDESNE DDENDPWLIR 790 800 810 820 830 840 KDHKKNKEKK KKKSIDPDSI QSALLASGLG SKRPSFSSTP VISPAPNSTP ANSNTNSNSS 850 860 870 880 890 900 LITSQDAVER AQQMKKDLLD KLEKLAEDLP PNTLDELIDE LGGPENVAEM TGRKGRVVSN 910 920 930 940 950 960 DDGSISYESR SELDVPVEIL NITEKQRFMD GDKNIAIISE AASSGISLQA DRRAKNQRRR 970 980 990 1000 1010 1020 VHMTLELPWS ADRAIQQFGR THRSNQVTAP EYVFLISELA GEQRFASIVA KRLESLGALT 1030 1040 1050 1060 1070 1080 HGDRRATESR DLSRFNFDNK YGRNALEIVM KSIVNLDSPM VSPPPDYPGE FFKDVRQGLI 1090 1100 1110 1120 1130 1140 GVGLINVEDR SGILTLDKDY NNIGKFLNRI LGMEVHQQNA LFQYFADTLT AVVQNAKKNG 1150 1160 1170 1180 1190 1200 RYDMGILDLG SGDEKVRKSD VKKFLTPGYS TSGHVELYTI SVERGMSWEE ATKIWAELTG 1210 1220 1230 1240 1250 1260 PDDGFYLSLQ IRNNKKTAIL VKEVNPKKKL FLVYRPNTGK QLKLEIYADL KKKYKKVVSD 1270 1280 1290 1300 1310 1320 DALMHWLDQY NSSADTCTHA YWRGNCKKAS LGLVCEIGLR CRTYYVLCGS VLSVWTKVEG 1330 1340 1350 1360 1370 1380 VLASVSGTNV KMQIVRLRTE DGQRIVGLII PANCVSPLVN LLSTSDQSQQ LAVQQKQLWQ 1390 QHHPQSITNL SNA
	Isoform 2 [UniParc]. Checksum: 4CB83A00B1DBEC22	FASTA	1,392	154,184
	10 20 30 40 50 60 MVEPGQDLLL AALSESGISP NDLFDIDGGD AGLATPMPTP SVQQSVPLSA LELGLETEAA 70 80 90 100 110 120 VPVKQEPETV PTPALLNVRQ PPSTTTFVLN QINHLPPLGS TIVMTKTPPV TTNRQTITLT 130 140 150 160 170 180 KFIQTTASTR PSVSAPTVRN AMTSAPSKDQ VQLKDLLKNN SLNELMKLKP PANIAQPVAT 190 200 210 220 230 240 AATDVSNGTV KKESSNKEGA RMWINDMKMR SFSPTMKVPV VKEDDEPEEE DEEEMGHAET 250 260 270 280 290 300 YAEYMPIKLK IGLRHPDAVV ETSSLSSVTP PDVWYKTSIS EETIDNGWLS ALQLEAITYA 310 320 330 340 350 360 AQQHETFLPN GDRAGFLIGD GAGVGKGRTI AGIIYENYLL SRKRALWFSV SNDLKYDAER 370 380 390 400 410 420 DLRDIGAKNI LVHSLNKFKY GKISSKHNGS VKKGVIFATY SSLIGESQSG GKYKTRLKQL 430 440 450 460 470 480 LHWCGDDFDG VIVFDECHKA KNLCPVGSSK PTKTGLAVLE LQNKLPKARV VYASATGASE 490 500 510 520 530 540 PRNMAYMNRL GIWGEGTPFR EFSDFIQAVE RRGVGAMEIV AMDMKLRGMY IARQLSFTGV 550 560 570 580 590 600 TFKIEEVLLS QSYVKMYNKA VKLWVIARER FQQAADLIDA EQRMKKSMWG QFWSAHQRFF 610 620 630 640 650 660 KYLCIASKVK RVVQLAREEI KNGKCVVIGL QSTGEARTLE ALEEGGGELN DFVSTAKGVL 670 680 690 700 710 720 QSLIEKHFPA PDRKKLYSLL GIDLTAPSNN SSPRDSPCKE NKIKKRKGEE ITREAKKARK 730 740 750 760 770 780 VGGLTGSSSD DSGSESDASD NEESDYESSK NMSSGDDDDF NPFLDESNED DENDPWLIRK 790 800 810 820 830 840 DHKKNKEKKK KKSIDPDSIQ SALLASGLGS KRPSFSSTPV ISPAPNSTPA NSNTNSNSSL 850 860 870 880 890 900 ITSQDAVERA QQMKKDLLDK LEKLAEDLPP NTLDELIDEL GGPENVAEMT GRKGRVVSND 910 920 930 940 950 960 DGSISYESRS ELDVPVEILN ITEKQRFMDG DKNIAIISEA ASSGISLQAD RRAKNQRRRV 970 980 990 1000 1010 1020 HMTLELPWSA DRAIQQFGRT HRSNQVTAPE YVFLISELAG EQRFASIVAK RLESLGALTH 1030 1040 1050 1060 1070 1080 GDRRATESRD LSRFNFDNKY GRNALEIVMK SIVNLDSPMV SPPPDYPGEF FKDVRQGLIG 1090 1100 1110 1120 1130 1140 VGLINVEDRS GILTLDKDYN NIGKFLNRIL GMEVHQQNAL FQYFADTLTA VVQNAKKNGR 1150 1160 1170 1180 1190 1200 YDMGILDLGS GDEKVRKSDV KKFLTPGYST SGHVELYTIS VERGMSWEEA TKIWAELTGP 1210 1220 1230 1240 1250 1260 DDGFYLSLQI RNNKKTAILV KEVNPKKKLF LVYRPNTGKQ LKLEIYADLK KKYKKVVSDD 1270 1280 1290 1300 1310 1320 ALMHWLDQYN SSADTCTHAY WRGNCKKASL GLVCEIGLRC RTYYVLCGSV LSVWTKVEGV 1330 1340 1350 1360 1370 1380 LASVSGTNVK MQIVRLRTED GQRIVGLIIP ANCVSPLVNL LSTSDQSQQL AVQQKQLWQQ 1390 HHPQSITNLS NA
	Isoform 3 [UniParc]. Checksum: 3682A9E4AB3A70E2	FASTA	1,391	154,057
	10 20 30 40 50 60 MVEPGQDLLL AALSESGISP NDLFDIDGGD AGLATPMPTP SVQQSVPLSA LELGLETEAA 70 80 90 100 110 120 VPVKQEPETV PTPALLNQQP PSTTTFVLNQ INHLPPLGST IVMTKTPPVT TNRQTITLTK 130 140 150 160 170 180 FIQTTASTRP SVSAPTVRNA MTSAPSKDQV QLKDLLKNNS LNELMKLKPP ANIAQPVATA 190 200 210 220 230 240 ATDVSNGTVK KESSNKEGAR MWINDMKMRS FSPTMKVPVV KEDDEPEEED EEEMGHAETY 250 260 270 280 290 300 AEYMPIKLKI GLRHPDAVVE TSSLSSVTPP DVWYKTSISE ETIDNGWLSA LQLEAITYAA 310 320 330 340 350 360 QQHETFLPNG DRAGFLIGDG AGVGKGRTIA GIIYENYLLS RKRALWFSVS NDLKYDAERD 370 380 390 400 410 420 LRDIGAKNIL VHSLNKFKYG KISSKHNGSV KKGVIFATYS SLIGESQSGG KYKTRLKQLL 430 440 450 460 470 480 HWCGDDFDGV IVFDECHKAK NLCPVGSSKP TKTGLAVLEL QNKLPKARVV YASATGASEP 490 500 510 520 530 540 RNMAYMNRLG IWGEGTPFRE FSDFIQAVER RGVGAMEIVA MDMKLRGMYI ARQLSFTGVT 550 560 570 580 590 600 FKIEEVLLSQ SYVKMYNKAV KLWVIARERF QQAADLIDAE QRMKKSMWGQ FWSAHQRFFK 610 620 630 640 650 660 YLCIASKVKR VVQLAREEIK NGKCVVIGLQ STGEARTLEA LEEGGGELND FVSTAKGVLQ 670 680 690 700 710 720 SLIEKHFPAP DRKKLYSLLG IDLTAPSNNS SPRDSPCKEN KIKKRKGEEI TREAKKARKV 730 740 750 760 770 780 GGLTGSSSDD SGSESDASDN EESDYESSKN MSSGDDDDFN PFLDESNEDD ENDPWLIRKD 790 800 810 820 830 840 HKKNKEKKKK KSIDPDSIQS ALLASGLGSK RPSFSSTPVI SPAPNSTPAN SNTNSNSSLI 850 860 870 880 890 900 TSQDAVERAQ QMKKDLLDKL EKLAEDLPPN TLDELIDELG GPENVAEMTG RKGRVVSNDD 910 920 930 940 950 960 GSISYESRSE LDVPVEILNI TEKQRFMDGD KNIAIISEAA SSGISLQADR RAKNQRRRVH 970 980 990 1000 1010 1020 MTLELPWSAD RAIQQFGRTH RSNQVTAPEY VFLISELAGE QRFASIVAKR LESLGALTHG 1030 1040 1050 1060 1070 1080 DRRATESRDL SRFNFDNKYG RNALEIVMKS IVNLDSPMVS PPPDYPGEFF KDVRQGLIGV 1090 1100 1110 1120 1130 1140 GLINVEDRSG ILTLDKDYNN IGKFLNRILG MEVHQQNALF QYFADTLTAV VQNAKKNGRY 1150 1160 1170 1180 1190 1200 DMGILDLGSG DEKVRKSDVK KFLTPGYSTS GHVELYTISV ERGMSWEEAT KIWAELTGPD 1210 1220 1230 1240 1250 1260 DGFYLSLQIR NNKKTAILVK EVNPKKKLFL VYRPNTGKQL KLEIYADLKK KYKKVVSDDA 1270 1280 1290 1300 1310 1320 LMHWLDQYNS SADTCTHAYW RGNCKKASLG LVCEIGLRCR TYYVLCGSVL SVWTKVEGVL 1330 1340 1350 1360 1370 1380 ASVSGTNVKM QIVRLRTEDG QRIVGLIIPA NCVSPLVNLL STSDQSQQLA VQQKQLWQQH 1390 HPQSITNLSN A
	Isoform 4 [UniParc]. Checksum: 28DAA87F2379ABE5	FASTA	732	80,852
	10 20 30 40 50 60 MVEPGQDLLL AALSESGISP NDLFDIDGGD AGLATPMPTP SVQQSVPLSA LELGLETEAA 70 80 90 100 110 120 VPVKQEPETV PTPALLNVRQ PPSTTTFVLN QINHLPPLGS TIVMTKTPPV TTNRQTITLT 130 140 150 160 170 180 KFIQTTASTR PSVSAPTVRN AMTSAPSKDQ VQLKDLLKNN SLNELMKLKP PANIAQPVAT 190 200 210 220 230 240 AATDVSNGTV KKESSNKEGA RMWINDMKMR SFSPTMKVPV VKEDDEPEEE DEEEMGHAET 250 260 270 280 290 300 YAEYMPIKLK IGLRHPDAVV ETSSLSSVTP PDVWYKTSIS EETIDNGWLS ALQLEAITYA 310 320 330 340 350 360 AQQHETFLPN GDRAGFLIGD GAGVGKGRTI AGIIYENYLL SRKRALWFSV SNDLKYDAER 370 380 390 400 410 420 DLRDIGAKNI LVHSLNKFKY GKISSKHNGS VKKGVIFATY SSLIGESQSG GKYKTRLKQL 430 440 450 460 470 480 LHWCGDDFDG VIVFDECHKA KNLCPVGSSK PTKTGLAVLE LQNKLPKARV VYASATGASE 490 500 510 520 530 540 PRNMAYMNRL GIWGEGTPFR EFSDFIQAVE RRGVGAMEIV AMDMKLRGMY IARQLSFTGV 550 560 570 580 590 600 TFKIEEVLLS QSYVKMYNKA VKLWVIARER FQQAADLIDA EQRMKKSMWG QFWSAHQRFF 610 620 630 640 650 660 KYLCIASKVK RVVQLAREEI KNGKCVVIGL QSTGEARTLE ALEEGGGELN DFVSTAKGVL 670 680 690 700 710 720 QSLIEKHFPA PDRKKLYSLL GIDLTAPSNN SSPRDSPCKE NKIKKRKGEE ITREAKKARK 730 MSLMRMMKMI PG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular and biological characterization of a new nuclear protein, MOP-3 which is highly expressed in human monocytes." Takayama K., Ukai Y., Fujii Y., Yoshimoto M. Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2). Tissue: Blood.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-793 (ISOFORM 3). Tissue: Placenta.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-783 (ISOFORM 2). Tissue: Teratocarcinoma.
[4]	"NovelFam3000 -- uncharacterized human protein domains conserved across model organisms." Kemmer D., Podowski R.M., Arenillas D., Lim J., Hodges E., Roth P., Sonnhammer E.L.L., Hoeoeg C., Wasserman W.W. BMC Genomics 7:48-48(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-1393 (ISOFORM 4).
[5]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-697, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[6]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-214 AND SER-794, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[7]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-794 AND SER-815, MASS SPECTROMETRY. Tissue: Leukemic T-cell.
[8]	"Lysine acetylation targets protein complexes and co-regulates major cellular functions." Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M. Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-149; LYS-413 AND LYS-1222, MASS SPECTROMETRY.
[9]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-754; SER-755 AND SER-794, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[10]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[11]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-754 AND SER-755, MASS SPECTROMETRY.
[12]	"The consensus coding sequences of human breast and colorectal cancers." Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E. Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract] Cited for: VARIANTS [LARGE SCALE ANALYSIS] SER-634; LYS-889 AND CYS-997.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB014772 mRNA. Translation: BAB19784.1. BC030544 mRNA. Translation: AAH30544.1. BC133704 mRNA. Translation: AAI33705.1. AK001695 mRNA. Translation: BAA91842.1. AY364255 mRNA. Translation: AAQ76814.1. Different initiation.
IPI	IPI00023649. IPI00879053. IPI00879170. IPI00879441.
RefSeq	NP_001161328.1. NM_001167856.1. NP_060653.3. NM_018183.3.
UniGene	Hs.7012.
3D structure databases
ProteinModelPortal	A3KN83.
ModBase	Search...
Protein-protein interaction databases
IntAct	A3KN83. 1 interaction.
STRING	9606.ENSP00000267176.
PTM databases
PhosphoSite	A3KN83.
Proteomic databases
PaxDb	A3KN83.
PeptideAtlas	A3KN83.
PRIDE	A3KN83.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000267176; ENSP00000267176; ENSG00000139697. ENST00000420886; ENSP00000387361; ENSG00000139697.
GeneID	55206.
KEGG	hsa:55206.
UCSC	uc001uet.2. human. uc001ueu.2. human. uc001uev.2. human.
Organism-specific databases
CTD	55206.
GeneCards	GC12M123774.
HGNC	HGNC:22973. SBNO1.
HPA	HPA042388.
neXtProt	NX_A3KN83.
PharmGKB	PA134967986.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG83182.
HOGENOM	HOG000043949.
HOVERGEN	HBG108461.
InParanoid	A3KN83.
OMA	DHKKSKD.
OrthoDB	EOG48WC16.
Gene expression databases
ArrayExpress	A3KN83.
Bgee	A3KN83.
CleanEx	HS_SBNO1.
Genevestigator	A3KN83.
Family and domain databases
InterPro	IPR026937. SBNO_Helicase_C_dom. IPR026741. SNO-like. [Graphical view]
PANTHER	PTHR12706. PTHR12706. 1 hit.
Pfam	PF13871. Helicase_C_4. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SBNO1. human.
GenomeRNAi	55206.
NextBio	59106.

Entry information

Entry name

SBNO1_HUMAN

Accession

Primary (citable) accession number: A3KN83
Secondary accession number(s): Q05C06 , Q3ZTS3, Q9H3T8, Q9NVB2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 3, 2007
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.