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A3KMN0

- A3KMN0_MOUSE

UniProt

A3KMN0 - A3KMN0_MOUSE

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Protein
Submitted name:

Zbtb16 protein

Gene

Zbtb16

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. double-stranded DNA binding Source: Ensembl
  2. metal ion binding Source: UniProtKB-KW
  3. sequence-specific DNA binding transcription factor activity Source: Ensembl

GO - Biological processi

  1. anterior/posterior pattern specification Source: MGI
  2. cartilage development Source: Ensembl
  3. embryonic digit morphogenesis Source: Ensembl
  4. embryonic hindlimb morphogenesis Source: MGI
  5. embryonic pattern specification Source: MGI
  6. forelimb morphogenesis Source: MGI
  7. hindlimb morphogenesis Source: MGI
  8. male germ-line stem cell asymmetric division Source: MGI
  9. negative regulation of cell proliferation Source: MGI
  10. negative regulation of transcription, DNA-templated Source: Ensembl
  11. positive regulation of apoptotic process Source: MGI
  12. positive regulation of cartilage development Source: Ensembl
  13. positive regulation of chondrocyte differentiation Source: Ensembl
  14. positive regulation of fat cell differentiation Source: Ensembl
  15. positive regulation of ossification Source: Ensembl
  16. positive regulation of transcription, DNA-templated Source: Ensembl
  17. protein localization to nucleus Source: Ensembl
  18. regulation of transcription, DNA-templated Source: MGI
  19. skeletal system development Source: MGI
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiREACT_199115. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
Zbtb16 proteinImported
Gene namesi
Name:Zbtb16Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:103222. Zbtb16.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. nuclear speck Source: Ensembl
  3. nucleus Source: MGI
  4. plasma membrane Source: Ensembl
  5. PML body Source: Ensembl
  6. transcriptional repressor complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriA3KMN0.

Family & Domainsi

Sequence similaritiesi

Contains 1 BTB (POZ) domain.UniRule annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiCOG5048.
HOVERGENiHBG057844.

Family and domain databases

Gene3Di3.30.160.60. 8 hits.
3.30.710.10. 1 hit.
InterProiIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00651. BTB. 1 hit.
PF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 9 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 8 hits.
PS50157. ZINC_FINGER_C2H2_2. 9 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A3KMN0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
KANQMRLAGT LCDVVIMVDS QEFHAHRTVL ACTSKMFEIL FHRNSQHYTL
60 70 80 90 100
DFLSPKTFQQ ILEYAYTATL QAKAEDLDDL LYAAEILEIE YLEEQCLKIL
110 120 130 140 150
ETIQASDDND TEATMADGGG EEEEDRKARY LKNIFISKHS SEESGYASVA
160 170 180 190 200
GQSLPGPMVD QSPSVSTSFG LSAMSPTKAA VDSLMSIGQS LLQGTLQPPA
210 220 230 240 250
GPEEPTLAGG GRHPGVAEVK MEMMQVDEAP GQDSPGAAES SISGGMGDKL
260 270 280 290 300
EERSKEGPGT PTRGSVITSA RELHYGREES GEQLSPPVEA GQGPPGRQEP
310 320 330 340 350
LAPPVEKHLG IYSVLPNHKA DAVLSMPSSV TSGLHVQPAL AVSMDFSTYG
360 370 380 390 400
GLLPQGFIQR ELFSKLGELA VGMKAESRPL GEQCSVCGVE LPDNEAVEQH
410 420 430 440 450
RKLHSGMKTY GCELCGKRFL DSLRLRMHLL AHSAGAKAFV CDQCGAQFSK
460 470 480 490 500
EDALETHRQT HTGTDMAVFC LLCGKRFQAQ SALQQHMEVH AGVRSYICSE
510 520 530 540 550
CNRTFPSHTA LKRHLRSHTG DHPYECEFCG SCFRDESTLK SHKRIHTGEK
560 570 580 590 600
PYECNGCGKK FSLKHQLETH YRVHTGEKPF ECKLCHQRSR DYSAMIKHLR
610 620 630 640 650
THNGASPYQC TICTEYCPSL SSMQKHMKGH KPEEIPPDWR IEKTYLYLCY

V
Length:651
Mass (Da):71,792
Last modified:April 3, 2007 - v1
Checksum:iFA780B23E87C395B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC132441 mRNA. Translation: AAI32442.1.
BC132443 mRNA. Translation: AAI32444.1.
UniGeneiMm.457803.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC132441 mRNA. Translation: AAI32442.1 .
BC132443 mRNA. Translation: AAI32444.1 .
UniGenei Mm.457803.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:103222. Zbtb16.

Phylogenomic databases

eggNOGi COG5048.
HOVERGENi HBG057844.

Enzyme and pathway databases

Reactomei REACT_199115. Antigen processing: Ubiquitination & Proteasome degradation.

Miscellaneous databases

NextBioi 35544710.
SOURCEi Search...

Gene expression databases

Genevestigatori A3KMN0.

Family and domain databases

Gene3Di 3.30.160.60. 8 hits.
3.30.710.10. 1 hit.
InterProi IPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
Pfami PF00651. BTB. 1 hit.
PF00096. zf-C2H2. 2 hits.
[Graphical view ]
SMARTi SM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 9 hits.
[Graphical view ]
SUPFAMi SSF54695. SSF54695. 1 hit.
PROSITEi PS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 8 hits.
PS50157. ZINC_FINGER_C2H2_2. 9 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.

Entry informationi

Entry nameiA3KMN0_MOUSE
AccessioniPrimary (citable) accession number: A3KMN0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: October 29, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)