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Protein
Submitted name:

Zbtb16 protein

Gene

Zbtb16

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • anterior/posterior pattern specification Source: MGI
  • cartilage development Source: MGI
  • embryonic hindlimb morphogenesis Source: MGI
  • embryonic pattern specification Source: MGI
  • forelimb morphogenesis Source: MGI
  • hemopoiesis Source: MGI
  • hindlimb morphogenesis Source: MGI
  • male germ-line stem cell asymmetric division Source: MGI
  • negative regulation of cell proliferation Source: MGI
  • negative regulation of transcription, DNA-templated Source: MGI
  • negative regulation of transcription from RNA polymerase II promoter Source: MGI
  • positive regulation of apoptotic process Source: MGI
  • positive regulation of cartilage development Source: MGI
  • positive regulation of chondrocyte differentiation Source: MGI
  • positive regulation of fat cell differentiation Source: MGI
  • positive regulation of ossification Source: MGI
  • positive regulation of transcription, DNA-templated Source: MGI
  • regulation of transcription, DNA-templated Source: MGI
  • skeletal system development Source: MGI

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zbtb16 proteinImported
Gene namesi
Name:Zbtb16Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:103222. Zbtb16.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 74BTBInterPro annotationAdd BLAST63
Domaini382 – 409C2H2-typeInterPro annotationAdd BLAST28
Domaini410 – 437C2H2-typeInterPro annotationAdd BLAST28
Domaini439 – 466C2H2-typeInterPro annotationAdd BLAST28
Domaini468 – 495C2H2-typeInterPro annotationAdd BLAST28
Domaini496 – 523C2H2-typeInterPro annotationAdd BLAST28
Domaini524 – 551C2H2-typeInterPro annotationAdd BLAST28
Domaini552 – 579C2H2-typeInterPro annotationAdd BLAST28
Domaini580 – 607C2H2-typeInterPro annotationAdd BLAST28
Domaini608 – 635C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOVERGENiHBG057844.

Family and domain databases

Gene3Di3.30.40.10. 2 hits.
InterProiView protein in InterPro
IPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
IPR013087. Znf_C2H2_type.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF00651. BTB. 1 hit.
SMARTiView protein in SMART
SM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 9 hits.
SUPFAMiSSF54695. SSF54695. 1 hit.
SSF57667. SSF57667. 4 hits.
PROSITEiView protein in PROSITE
PS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 8 hits.
PS50157. ZINC_FINGER_C2H2_2. 9 hits.

Sequencei

Sequence statusi: Fragment.

A3KMN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
KANQMRLAGT LCDVVIMVDS QEFHAHRTVL ACTSKMFEIL FHRNSQHYTL
60 70 80 90 100
DFLSPKTFQQ ILEYAYTATL QAKAEDLDDL LYAAEILEIE YLEEQCLKIL
110 120 130 140 150
ETIQASDDND TEATMADGGG EEEEDRKARY LKNIFISKHS SEESGYASVA
160 170 180 190 200
GQSLPGPMVD QSPSVSTSFG LSAMSPTKAA VDSLMSIGQS LLQGTLQPPA
210 220 230 240 250
GPEEPTLAGG GRHPGVAEVK MEMMQVDEAP GQDSPGAAES SISGGMGDKL
260 270 280 290 300
EERSKEGPGT PTRGSVITSA RELHYGREES GEQLSPPVEA GQGPPGRQEP
310 320 330 340 350
LAPPVEKHLG IYSVLPNHKA DAVLSMPSSV TSGLHVQPAL AVSMDFSTYG
360 370 380 390 400
GLLPQGFIQR ELFSKLGELA VGMKAESRPL GEQCSVCGVE LPDNEAVEQH
410 420 430 440 450
RKLHSGMKTY GCELCGKRFL DSLRLRMHLL AHSAGAKAFV CDQCGAQFSK
460 470 480 490 500
EDALETHRQT HTGTDMAVFC LLCGKRFQAQ SALQQHMEVH AGVRSYICSE
510 520 530 540 550
CNRTFPSHTA LKRHLRSHTG DHPYECEFCG SCFRDESTLK SHKRIHTGEK
560 570 580 590 600
PYECNGCGKK FSLKHQLETH YRVHTGEKPF ECKLCHQRSR DYSAMIKHLR
610 620 630 640 650
THNGASPYQC TICTEYCPSL SSMQKHMKGH KPEEIPPDWR IEKTYLYLCY

V
Length:651
Mass (Da):71,792
Last modified:April 3, 2007 - v1
Checksum:iFA780B23E87C395B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC132441 mRNA. Translation: AAI32442.1.
BC132443 mRNA. Translation: AAI32444.1.
UniGeneiMm.457803.

Similar proteinsi

Entry informationi

Entry nameiA3KMN0_MOUSE
AccessioniPrimary (citable) accession number: A3KMN0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: September 27, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)