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A3KMN0

- A3KMN0_MOUSE

UniProt

A3KMN0 - A3KMN0_MOUSE

Protein
Submitted name:

Zbtb16 protein

Gene

Zbtb16

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (03 Apr 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. double-stranded DNA binding Source: Ensembl
    2. metal ion binding Source: UniProtKB-KW
    3. protein binding Source: MGI
    4. sequence-specific DNA binding transcription factor activity Source: Ensembl

    GO - Biological processi

    1. anterior/posterior pattern specification Source: MGI
    2. cartilage development Source: Ensembl
    3. embryonic digit morphogenesis Source: Ensembl
    4. embryonic hindlimb morphogenesis Source: MGI
    5. embryonic pattern specification Source: MGI
    6. forelimb morphogenesis Source: MGI
    7. hindlimb morphogenesis Source: MGI
    8. male germ-line stem cell asymmetric division Source: MGI
    9. negative regulation of cell proliferation Source: MGI
    10. negative regulation of transcription, DNA-templated Source: Ensembl
    11. positive regulation of apoptotic process Source: MGI
    12. positive regulation of cartilage development Source: Ensembl
    13. positive regulation of chondrocyte differentiation Source: Ensembl
    14. positive regulation of fat cell differentiation Source: Ensembl
    15. positive regulation of ossification Source: Ensembl
    16. positive regulation of transcription, DNA-templated Source: Ensembl
    17. protein localization to nucleus Source: Ensembl
    18. regulation of transcription, DNA-templated Source: MGI
    19. skeletal system development Source: MGI

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    ReactomeiREACT_199115. Antigen processing: Ubiquitination & Proteasome degradation.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Zbtb16 proteinImported
    Gene namesi
    Name:Zbtb16Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:103222. Zbtb16.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Ensembl
    2. nuclear speck Source: Ensembl
    3. nucleus Source: MGI
    4. plasma membrane Source: Ensembl
    5. PML body Source: Ensembl
    6. transcriptional repressor complex Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriA3KMN0.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 BTB (POZ) domain.UniRule annotation

    Keywords - Domaini

    Zinc-fingerSAAS annotation

    Phylogenomic databases

    eggNOGiCOG5048.
    HOVERGENiHBG057844.
    InParanoidiA3KMN0.

    Family and domain databases

    Gene3Di3.30.160.60. 8 hits.
    3.30.710.10. 1 hit.
    InterProiIPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR013069. BTB_POZ.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF00651. BTB. 1 hit.
    PF00096. zf-C2H2. 2 hits.
    [Graphical view]
    SMARTiSM00225. BTB. 1 hit.
    SM00355. ZnF_C2H2. 9 hits.
    [Graphical view]
    SUPFAMiSSF54695. SSF54695. 1 hit.
    PROSITEiPS50097. BTB. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 8 hits.
    PS50157. ZINC_FINGER_C2H2_2. 9 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    A3KMN0-1 [UniParc]FASTAAdd to Basket

    « Hide

    KANQMRLAGT LCDVVIMVDS QEFHAHRTVL ACTSKMFEIL FHRNSQHYTL    50
    DFLSPKTFQQ ILEYAYTATL QAKAEDLDDL LYAAEILEIE YLEEQCLKIL 100
    ETIQASDDND TEATMADGGG EEEEDRKARY LKNIFISKHS SEESGYASVA 150
    GQSLPGPMVD QSPSVSTSFG LSAMSPTKAA VDSLMSIGQS LLQGTLQPPA 200
    GPEEPTLAGG GRHPGVAEVK MEMMQVDEAP GQDSPGAAES SISGGMGDKL 250
    EERSKEGPGT PTRGSVITSA RELHYGREES GEQLSPPVEA GQGPPGRQEP 300
    LAPPVEKHLG IYSVLPNHKA DAVLSMPSSV TSGLHVQPAL AVSMDFSTYG 350
    GLLPQGFIQR ELFSKLGELA VGMKAESRPL GEQCSVCGVE LPDNEAVEQH 400
    RKLHSGMKTY GCELCGKRFL DSLRLRMHLL AHSAGAKAFV CDQCGAQFSK 450
    EDALETHRQT HTGTDMAVFC LLCGKRFQAQ SALQQHMEVH AGVRSYICSE 500
    CNRTFPSHTA LKRHLRSHTG DHPYECEFCG SCFRDESTLK SHKRIHTGEK 550
    PYECNGCGKK FSLKHQLETH YRVHTGEKPF ECKLCHQRSR DYSAMIKHLR 600
    THNGASPYQC TICTEYCPSL SSMQKHMKGH KPEEIPPDWR IEKTYLYLCY 650
    V 651
    Length:651
    Mass (Da):71,792
    Last modified:April 3, 2007 - v1
    Checksum:iFA780B23E87C395B
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC132441 mRNA. Translation: AAI32442.1.
    BC132443 mRNA. Translation: AAI32444.1.
    UniGeneiMm.457803.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC132441 mRNA. Translation: AAI32442.1 .
    BC132443 mRNA. Translation: AAI32444.1 .
    UniGenei Mm.457803.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:103222. Zbtb16.

    Phylogenomic databases

    eggNOGi COG5048.
    HOVERGENi HBG057844.
    InParanoidi A3KMN0.

    Enzyme and pathway databases

    Reactomei REACT_199115. Antigen processing: Ubiquitination & Proteasome degradation.

    Miscellaneous databases

    NextBioi 35544710.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori A3KMN0.

    Family and domain databases

    Gene3Di 3.30.160.60. 8 hits.
    3.30.710.10. 1 hit.
    InterProi IPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR013069. BTB_POZ.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF00651. BTB. 1 hit.
    PF00096. zf-C2H2. 2 hits.
    [Graphical view ]
    SMARTi SM00225. BTB. 1 hit.
    SM00355. ZnF_C2H2. 9 hits.
    [Graphical view ]
    SUPFAMi SSF54695. SSF54695. 1 hit.
    PROSITEi PS50097. BTB. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 8 hits.
    PS50157. ZINC_FINGER_C2H2_2. 9 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.

    Entry informationi

    Entry nameiA3KMN0_MOUSE
    AccessioniPrimary (citable) accession number: A3KMN0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 3, 2007
    Last sequence update: April 3, 2007
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)