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Protein
Submitted name:

Fanconi anemia, complementation group F

Gene

FANCF

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Fanconi anemia, complementation group FImported
Submitted name:
cDNA FLJ10854 fis, clone NT2RP4001507, highly similar to Fanconi anemia group F proteinImported
Gene namesi
Name:FANCFImported
ORF Names:hCG_1646608Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28001.

Expressioni

Gene expression databases

BgeeiENSG00000183161.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000330875.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IKQV. Eukaryota.
ENOG4111WMC. LUCA.
HOVERGENiHBG051550.
KOiK10893.
OMAiWARYLRH.
OrthoDBiEOG091G18J8.

Family and domain databases

InterProiIPR025825. FANCF.
[Graphical view]
ProDomiPD321645. PD321645. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

A3KME0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESLLQHLDR FSELLAVSST TYVSTWDPAT VRRALQWARY LRHIHRRFGR
60 70 80 90 100
HGPIRTALER RLHNQWRQEG GFGRGPVPGL ANFQALGHCD VLLSLRLLEN
110 120 130 140 150
RALGDAARYH LVQQLFPGPG VRDADEETLQ ESLARLARRR SAVHMLRFNG
160 170 180 190 200
YRENPNLQED SLMKTQAELL LERLQEVGKA EAERPARFLS SLWERLPQNN
210 220 230 240 250
FLKVIAVALL QPPLSRRPQE ELEPGIHKSP GEGSQVLVHW LLGNSEVFAA
260 270 280 290 300
FCRALPAGLL TLVTSRHPAL SPVYLGLLTD WGQRLHYDLQ KGIWVGTESQ
310 320 330 340 350
DVPWEELHNR FQSLCQAPPP LKDKVLTALE TCKAQDGDFE VPGLSIWTDL
360 370
LLALRSGAFR KRQVLGLSAG LSSV
Length:374
Mass (Da):42,254
Last modified:April 3, 2007 - v1
Checksum:i1F295CD1FBE6ED7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063038 mRNA. Translation: AAH63038.1.
AK001716 mRNA. Translation: BAG50967.1.
CH471064 Genomic DNA. Translation: EAW68319.1.
RefSeqiNP_073562.1. NM_022725.3.
UniGeneiHs.632151.

Genome annotation databases

GeneIDi2188.
KEGGihsa:2188.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC063038 mRNA. Translation: AAH63038.1.
AK001716 mRNA. Translation: BAG50967.1.
CH471064 Genomic DNA. Translation: EAW68319.1.
RefSeqiNP_073562.1. NM_022725.3.
UniGeneiHs.632151.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000330875.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2188.
KEGGihsa:2188.

Organism-specific databases

CTDi2188.
PharmGKBiPA28001.

Phylogenomic databases

eggNOGiENOG410IKQV. Eukaryota.
ENOG4111WMC. LUCA.
HOVERGENiHBG051550.
KOiK10893.
OMAiWARYLRH.
OrthoDBiEOG091G18J8.

Miscellaneous databases

ChiTaRSiFANCF. human.
GenomeRNAii2188.

Gene expression databases

BgeeiENSG00000183161.

Family and domain databases

InterProiIPR025825. FANCF.
[Graphical view]
ProDomiPD321645. PD321645. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiA3KME0_HUMAN
AccessioniPrimary (citable) accession number: A3KME0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: November 2, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.