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A3GHR1

- A3GHR1_PICST

UniProt

A3GHR1 - A3GHR1_PICST

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Protein

Glutamate decarboxylase

Gene

DCE1

Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:DCE1Imported
ORF Names:PICST_40180Imported
OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)Imported
Taxonomic identifieri322104 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces
ProteomesiUP000002258: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi4924.PICST_40180.

Structurei

3D structure databases

ProteinModelPortaliA3GHR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
InParanoidiA3GHR1.
KOiK01580.
OMAiILSNLWH.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

A3GHR1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTLSKHIDAE VLETALLKNA VKSKLTKREE YISQYDSEKL VPKYEIPSHS
60 70 80 90 100
SSGELVYKYL SEELTLDGNP TLNLASFVNT SCDDTQLKLI TDNIVKNLAD
110 120 130 140 150
NDEYPSLIDF QQRCISILSN LWHAPTKVDS TGKKVINSIG TATTGSSEAI
160 170 180 190 200
MLAGLALKKR WQEKRKAAGK STENPNIIMA SVAQVALEKF ARYFDVEDRL
210 220 230 240 250
IHVNEESGHL IDISKIKEAV DENTIGIFVI LGSTFTGAFE PVEQISHLLD
260 270 280 290 300
EIEKEKGLDV RIHVDGASGG FVAPFVYPHL KWDFQIPRVD SINTSGHKFG
310 320 330 340 350
LTTAGLGWVI WKDSELLPKS LKFSLDYLGG VEETFGLNFS RAGFPVVLQY
360 370 380 390 400
YNFLTLGKEG YSKIFNSCIS NARLLSNILE KSEYFEVLSV IHKEVSDERA
410 420 430 440 450
AQVYTKVHHV DSKHTKEAIH NEKFEPGLPV VAFRFSKELR ETYPEIPQGI
460 470 480 490 500
FSTLLRNKGY IVPNYHLPPD EGEKEILRVV VRQSLSLNLL EKLVKDSIEA
510 520 530 540 550
VELLIKSCKD VRDVIHAKHT TEEVDKGLVY SLLLSISSGG VEDKKEIQHE
560
QLKQASVNPK HKRRYRATC
Length:569
Mass (Da):63,950
Last modified:June 16, 2009 - v2
Checksum:i866EBC8F0D1A0A32
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAVQ01000002 Genomic DNA. Translation: EAZ63096.2.
RefSeqiXP_001387119.2. XM_001387082.1.

Genome annotation databases

GeneIDi4851810.
KEGGipic:PICST_40180.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAVQ01000002 Genomic DNA. Translation: EAZ63096.2 .
RefSeqi XP_001387119.2. XM_001387082.1.

3D structure databases

ProteinModelPortali A3GHR1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 4924.PICST_40180.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4851810.
KEGGi pic:PICST_40180.

Phylogenomic databases

HOGENOMi HOG000070228.
InParanoidi A3GHR1.
KOi K01580.
OMAi ILSNLWH.
OrthoDBi EOG7P2Z22.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 2 hits.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545Imported.

Entry informationi

Entry nameiA3GHR1_PICST
AccessioniPrimary (citable) accession number: A3GHR1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: June 16, 2009
Last modified: October 29, 2014
This is version 47 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3