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A3GHR1

- A3GHR1_PICST

UniProt

A3GHR1 - A3GHR1_PICST

Protein

Glutamate decarboxylase

Gene

DCE1

Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 2 (16 Jun 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Name:DCE1Imported
    ORF Names:PICST_40180Imported
    OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)Imported
    Taxonomic identifieri322104 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces
    ProteomesiUP000002258: Chromosome 1

    Interactioni

    Protein-protein interaction databases

    STRINGi4924.PICST_40180.

    Structurei

    3D structure databases

    ProteinModelPortaliA3GHR1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiILSNLWH.
    OrthoDBiEOG7P2Z22.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 2 hits.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A3GHR1-1 [UniParc]FASTAAdd to Basket

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    MTLSKHIDAE VLETALLKNA VKSKLTKREE YISQYDSEKL VPKYEIPSHS    50
    SSGELVYKYL SEELTLDGNP TLNLASFVNT SCDDTQLKLI TDNIVKNLAD 100
    NDEYPSLIDF QQRCISILSN LWHAPTKVDS TGKKVINSIG TATTGSSEAI 150
    MLAGLALKKR WQEKRKAAGK STENPNIIMA SVAQVALEKF ARYFDVEDRL 200
    IHVNEESGHL IDISKIKEAV DENTIGIFVI LGSTFTGAFE PVEQISHLLD 250
    EIEKEKGLDV RIHVDGASGG FVAPFVYPHL KWDFQIPRVD SINTSGHKFG 300
    LTTAGLGWVI WKDSELLPKS LKFSLDYLGG VEETFGLNFS RAGFPVVLQY 350
    YNFLTLGKEG YSKIFNSCIS NARLLSNILE KSEYFEVLSV IHKEVSDERA 400
    AQVYTKVHHV DSKHTKEAIH NEKFEPGLPV VAFRFSKELR ETYPEIPQGI 450
    FSTLLRNKGY IVPNYHLPPD EGEKEILRVV VRQSLSLNLL EKLVKDSIEA 500
    VELLIKSCKD VRDVIHAKHT TEEVDKGLVY SLLLSISSGG VEDKKEIQHE 550
    QLKQASVNPK HKRRYRATC 569
    Length:569
    Mass (Da):63,950
    Last modified:June 16, 2009 - v2
    Checksum:i866EBC8F0D1A0A32
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAVQ01000002 Genomic DNA. Translation: EAZ63096.2.
    RefSeqiXP_001387119.2. XM_001387082.1.

    Genome annotation databases

    GeneIDi4851810.
    KEGGipic:PICST_40180.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAVQ01000002 Genomic DNA. Translation: EAZ63096.2 .
    RefSeqi XP_001387119.2. XM_001387082.1.

    3D structure databases

    ProteinModelPortali A3GHR1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4924.PICST_40180.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4851810.
    KEGGi pic:PICST_40180.

    Phylogenomic databases

    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi ILSNLWH.
    OrthoDBi EOG7P2Z22.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 2 hits.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545Imported.

    Entry informationi

    Entry nameiA3GHR1_PICST
    AccessioniPrimary (citable) accession number: A3GHR1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 3, 2007
    Last sequence update: June 16, 2009
    Last modified: October 1, 2014
    This is version 46 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3