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Protein

Glutamate decarboxylase

Gene

DCE1

Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:DCE1Imported
ORF Names:PICST_40180Imported
OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)Imported
Taxonomic identifieri322104 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces
Proteomesi
  • UP000002258 Componenti: Chromosome 1

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei298N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi322104.XP_001387119.2

Structurei

3D structure databases

ProteinModelPortaliA3GHR1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1383 Eukaryota
COG0076 LUCA
HOGENOMiHOG000070228
InParanoidiA3GHR1
KOiK01580
OMAiRPNLVMG
OrthoDBiEOG092C1P0W

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 2 hits
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

A3GHR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLSKHIDAE VLETALLKNA VKSKLTKREE YISQYDSEKL VPKYEIPSHS
60 70 80 90 100
SSGELVYKYL SEELTLDGNP TLNLASFVNT SCDDTQLKLI TDNIVKNLAD
110 120 130 140 150
NDEYPSLIDF QQRCISILSN LWHAPTKVDS TGKKVINSIG TATTGSSEAI
160 170 180 190 200
MLAGLALKKR WQEKRKAAGK STENPNIIMA SVAQVALEKF ARYFDVEDRL
210 220 230 240 250
IHVNEESGHL IDISKIKEAV DENTIGIFVI LGSTFTGAFE PVEQISHLLD
260 270 280 290 300
EIEKEKGLDV RIHVDGASGG FVAPFVYPHL KWDFQIPRVD SINTSGHKFG
310 320 330 340 350
LTTAGLGWVI WKDSELLPKS LKFSLDYLGG VEETFGLNFS RAGFPVVLQY
360 370 380 390 400
YNFLTLGKEG YSKIFNSCIS NARLLSNILE KSEYFEVLSV IHKEVSDERA
410 420 430 440 450
AQVYTKVHHV DSKHTKEAIH NEKFEPGLPV VAFRFSKELR ETYPEIPQGI
460 470 480 490 500
FSTLLRNKGY IVPNYHLPPD EGEKEILRVV VRQSLSLNLL EKLVKDSIEA
510 520 530 540 550
VELLIKSCKD VRDVIHAKHT TEEVDKGLVY SLLLSISSGG VEDKKEIQHE
560
QLKQASVNPK HKRRYRATC
Length:569
Mass (Da):63,950
Last modified:June 16, 2009 - v2
Checksum:i866EBC8F0D1A0A32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAVQ01000002 Genomic DNA Translation: EAZ63096.2
RefSeqiXP_001387119.2, XM_001387082.1

Genome annotation databases

EnsemblFungiiEAZ63096; EAZ63096; PICST_40180
GeneIDi4851810
KEGGipic:PICST_40180

Similar proteinsi

Entry informationi

Entry nameiA3GHR1_PICST
AccessioniPrimary (citable) accession number: A3GHR1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: June 16, 2009
Last modified: April 25, 2018
This is version 70 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health