A3GHM9 (A3GHM9_PICST) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histone deacetylase PIRNR PIRNR037913
EC=3.5.1.98 PIRNR PIRNR037913

Gene names

Name:	RPD3 EMBL EAZ62851.1
ORF Names:	PICST_81035 EMBL EAZ62851.1

Organism

Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis) [Complete proteome]

Taxonomic identifier

322104 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Scheffersomyces

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone. PIRNR PIRNR037913
Subcellular location	Nucleus By similarity PIRNR PIRNR037913.
Sequence similarities	Belongs to the histone deacetylase family. HD Type 1 subfamily. PIRNR PIRNR037913
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
Biological process	Transcription Transcription regulation PIRNR PIRNR037913
Cellular component	Nucleus PIRNR PIRNR037913
Molecular function	Chromatin regulator PIRNR PIRNR037913 Hydrolase PIRNR PIRNR037913 SAAS SAAS000286 EMBL EAZ62851.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	NAD-dependent histone deacetylase activity (H3-K14 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H3-K9 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H4-K16 specific) Inferred from electronic annotation. Source: EC histone deacetylase activity (H3-K16 specific) Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3GHM9 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 3F1836F1CBFD64DF	FASTA	500	56,189
	10 20 30 40 50 60 MYVQLPFDEL KVDPTQKKRI AYFYDADIGN YAYGAGHPMK PHRIRMAHSL IMNYGLYKKM 70 80 90 100 110 120 EIYRAKPATK QEMCQFHTDE YIDFLSRVGP DNLDMFAKEQ IKFNVGDDCP VFDGLFEYCG 130 140 150 160 170 180 ISGGGSMEGA ARLNRGKCDI AINYAGGLHH AKKSEASGFC YLNDIVLGII ELLRYHPRVL 190 200 210 220 230 240 YIDIDVHHGD GVEEAFYTTD RVMTASFHKY GEFFPGTGEL RDIGVGKGKY YSVNVPLRDG 250 260 270 280 290 300 IDDATYKSVF EPLISKIIEW YQPSAIVLQC GGDSLSGDRL GCFNLSMAGH ANCINFVKSF 310 320 330 340 350 360 NIPMMVVGGG GYTMRNVART WAFESGLLNN VILPSELPYN EYYEYYGPDY KLDVRPSNMY 370 380 390 400 410 420 NTNSPEFLNK ILTSIITNLE NTKHAPSVQM NEVPRDAEDL GDVDEDTKEA IDTKGGSQQA 430 440 450 460 470 480 RDEQIQPENE FYDEDDKDEG EKMISVPDAS IEVKEKPIER APAEEAKDVE DAKDAKDVPS 490 500 ASVLTKEELD EIEELNKGVN

References

[1]

"Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis." Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A., Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S., Passoth V., Richardson P.M. Nat. Biotechnol. 25:319-326(2007) [PubMed: 17334359] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAVQ01000002 Genomic DNA. Translation: EAZ62851.1.
RefSeq	XP_001386874.1. XM_001386837.1.
3D structure databases
ProteinModelPortal	A3GHM9.
ModBase	Search...
Protein-protein interaction databases
STRING	A3GHM9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4851778.
GenomeReviews	Gene locus RPD3 in contig CM000437_GR.
KEGG	pic:PICST_81035.
Phylogenomic databases
eggNOG	fuNOG05981.
HOGENOM	HBG396919.
OMA	IPEDAPH.
OrthoDB	EOG4RV60J.
Family and domain databases
InterPro	IPR000286. His_deacetylse. IPR003084. His_deacetylse_1. IPR023801. His_deacetylse_dom. [Graphical view]
Gene3D	G3DSA:3.40.800.20. His_deacetylse. 1 hit.
KO	K06067.
PANTHER	PTHR10625. His_deacetylse. 1 hit.
Pfam	PF00850. Hist_deacetyl. 1 hit. [Graphical view]
PIRSF	PIRSF037913. His_deacetylse_1. 1 hit.
PRINTS	PR01270. HDASUPER. PR01271. HISDACETLASE.
ProtoNet	Search...

Entry information

Entry name

A3GHM9_PICST

Accession

Primary (citable) accession number: A3GHM9

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)