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Protein

Histone deacetylase

Gene

HOS3

Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorSAAS annotation, HydrolaseSAAS annotationImported
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseSAAS annotation (EC:3.5.1.98SAAS annotation)
Gene namesi
Name:HOS3Imported
ORF Names:PICST_34373Imported
OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)Imported
Taxonomic identifieri322104 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces
Proteomesi
  • UP000002258 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi322104.XP_001387967.2

Structurei

3D structure databases

ProteinModelPortaliA3GGJ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini164 – 567Hist_deacetylInterPro annotationAdd BLAST404

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili438 – 472Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1343 Eukaryota
COG0123 LUCA
HOGENOMiHOG000246666
InParanoidiA3GGJ4
KOiK11484
OMAiNASTCIM
OrthoDBiEOG092C345D

Family and domain databases

InterProiView protein in InterPro
IPR000286 His_deacetylse
IPR023801 His_deacetylse_dom
IPR023696 Ureohydrolase_dom_sf
PANTHERiPTHR10625 PTHR10625, 1 hit
PfamiView protein in Pfam
PF00850 Hist_deacetyl, 1 hit
PRINTSiPR01270 HDASUPER
SUPFAMiSSF52768 SSF52768, 3 hits

Sequencei

Sequence statusi: Complete.

A3GGJ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLQETLSKH NDSEESLISQ FETTLTIRPT ANDDDEVKDI TIDQSTVLHN
60 70 80 90 100
NTFNYTRDQS IVDIDELEEE ELISEQIPKF KTRRRYSLLP AHATKITTKN
110 120 130 140 150
PGGLDGYYSH IGPKFEHILK PSPLIDQSLS NDSDKTLVIL SPYSTEHAFG
160 170 180 190 200
RKWVTKSYLS TIFERPQRLL ASCIGVASAL TMFPFHYKLI NSTRRGSIFA
210 220 230 240 250
SHVRKIHGKN WPRKLFELCI ESHDKLLNDT LEVPEDWNSG DIYVNPRTLN
260 270 280 290 300
AIEGVIGTIE TAVDSLYGGT NAEDVEDNHN LAFVVIRPPG HHSHACLPSG
310 320 330 340 350
FCLLNNVQIG IEYAFERYGV THCVILDIDL HHGDGSQDIC WERAGFQGDY
360 370 380 390 400
GQDEDDEIDP KSNPRDDYGK RFATFPKVGY FSLHDIKSYP TELGYATKEN
410 420 430 440 450
IKNASTCIMD HDLNIWNVHL QEWSKEEEFY KHYQTKYVAL LNRANQFLNT
460 470 480 490 500
AKKQYEQQYQ DYLNNLAKYN KFLLKPHLYQ GQSLEKPVAP PPFKPLITIS
510 520 530 540 550
AGFDASEYEN PQMQRHGINV PTSFYATFTH DVVKLAKIHT DGRVISFLEG
560 570 580 590 600
GYSDGALTTG IFSHLIGLNN DEEFLWNPTW GTDQVMKELT KGCKKNWAPY
610 620 630 640 650
KKPQSDITIW ANEVIKLGRA MMPNAILPSN YVYQYQEEEL KAPVNKMVKE
660 670 680 690 700
LIAHNVNLGE ISNSPLKKDP EDERKVMRHT RSYYKKMANA QKQQSIETDS

AKHNLPKY
Length:708
Mass (Da):80,983
Last modified:June 16, 2009 - v2
Checksum:iAFABDD13F927138D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAVQ01000001 Genomic DNA Translation: EAZ63944.2
RefSeqiXP_001387967.2, XM_001387930.1

Genome annotation databases

EnsemblFungiiEAZ63944; EAZ63944; PICST_34373
GeneIDi4851393
KEGGipic:PICST_34373

Similar proteinsi

Entry informationi

Entry nameiA3GGJ4_PICST
AccessioniPrimary (citable) accession number: A3GGJ4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: June 16, 2009
Last modified: March 28, 2018
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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