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Protein

Peptidyl-prolyl cis-trans isomerase

Gene

cgd2_4120

Organism
Cryptosporidium parvum (strain Iowa II)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.UniRule annotation

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, RotamasePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)
Short name:
PPIaseUniRule annotation
Gene namesi
ORF Names:cgd2_4120Imported
OrganismiCryptosporidium parvum (strain Iowa II)Imported
Taxonomic identifieri353152 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaCryptosporidiidaeCryptosporidium
Proteomesi
  • UP000006726 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiCryptoDB:cgd2_4120.

Interactioni

Protein-protein interaction databases

STRINGi353152.XP_001388243.1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PLUX-ray1.82A3-170[»]
2POYX-ray1.80A/B/C3-170[»]
ProteinModelPortaliA3FQA7.
SMRiA3FQA7.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA3FQA7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 170PPIase cyclophilin-typeInterPro annotationAdd BLAST164

Sequence similaritiesi

Belongs to the cyclophilin-type PPIase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0865. Eukaryota.
COG0652. LUCA.
HOGENOMiHOG000065981.
InParanoidiA3FQA7.
KOiK01802.
OMAiFFINFKD.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiView protein in InterPro
IPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
PANTHERiPTHR11071. PTHR11071. 1 hit.
PfamiView protein in Pfam
PF00160. Pro_isomerase. 1 hit.
PIRSFiPIRSF001467. Peptidylpro_ismrse. 1 hit.
PRINTSiPR00153. CSAPPISMRASE.
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiView protein in PROSITE
PS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A3FQA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPNPVVYFDI SIGQTPAGRI TMELFADKVP ITAENFRALC TGEKGMGQSG
60 70 80 90 100
KPLCYTGSFF HRIIPQFMIQ GGDFTRGDGT GGESIYGSKF RDENFVYTHD
110 120 130 140 150
APFLLSMANA GPNTNGSQFF ITTVPCPWLD GKHVVFGKVL EGMEVVKSIE
160 170
KCGSQNGKPT KSVCITASGV LS
Length:172
Mass (Da):18,544
Last modified:April 3, 2007 - v1
Checksum:i709330D5E8C8AAC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEE01000005 Genomic DNA. Translation: EAZ51416.1.
RefSeqiXP_001388243.1. XM_001388206.1.

Genome annotation databases

EnsemblProtistsiEAZ51416; EAZ51416; cgd2_4120.
GeneIDi3373663.
KEGGicpv:cgd2_4120.

Similar proteinsi

Entry informationi

Entry nameiA3FQA7_CRYPI
AccessioniPrimary (citable) accession number: A3FQA7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: August 30, 2017
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported