A3F3F2 (A3F3F2_BACSU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate synthase HAMAP MF_00110
EC=4.2.3.4 HAMAP MF_00110

Gene names

Name:

aroB HAMAP MF_00110 EMBL ABN13195.1

Organism

Bacillus subtilis subsp. subtilis str. NCIB 3610 EMBL ABN13195.1

Taxonomic identifier

535026 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	362 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110
Cofactor	Divalent metal cations By similarity. HAMAP MF_00110 NAD By similarity. HAMAP MF_00110
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110
Subunit structure	Monomer By similarity. HAMAP MF_00110
Subcellular location	Cytoplasm By similarity HAMAP MF_00110.
Sequence similarities	Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00110
Cellular component	Cytoplasm HAMAP MF_00110
Ligand	NAD HAMAP MF_00110
Molecular function	Lyase HAMAP MF_00110 EMBL ABN13195.1
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-dehydroquinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3F3F2 [UniParc]. Last modified December 16, 2008. Version 1. Checksum: A0093C7730916AAC	FASTA	362	40,817
	10 20 30 40 50 60 MKTLHVQTAS SSYPVFIGQG IRKKACELLT SLNRPLTRIM FVTDEEVDRL YGDEMLHLLQ 70 80 90 100 110 120 EKWPVKKVTV PSGEQAKSMD MYTKLQSEAI RFHMDRSSCI IAFGGGVVGD LAGFVAATFM 130 140 150 160 170 180 RGIDFIQMPT TLLAHDSAVG GKVAVNHPLG KNLIGAFYQP KAVLYDTDFL RSLPEKELRS 190 200 210 220 230 240 GMAEVIKHAF IYDRAFLEEL LNIHSLRDIT NDQLNDMIFK GISIKASVVQ QDEKEEGIRA 250 260 270 280 290 300 YLNFGHTLGH AVEAEYGYGQ ITHGDAVALG MQFALYISEK TVGCEMDRKR LVSWLKSLGY 310 320 330 340 350 360 PSQIRKETET SVLLNRMMND KKTRGGKIQF IVLNELGKVA DHTFSRNELE SWLNKWRLEE TS

References

[1]

"The origins of 168, W23, and other Bacillus subtilis legacy strains." Zeigler D.R., Pragai Z., Rodriguez S., Chevreux B., Muffler A., Albert T., Bai R., Wyss M., Perkins J.B. J. Bacteriol. 190:6983-6995(2008) [PubMed: 18723616] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: NCIB 3610 EMBL ABN13195.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EF191536 Genomic DNA. Translation: ABN13195.1.
3D structure databases
ProteinModelPortal	A3F3F2.
SMR	A3F3F2. Positions 1-358.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	36928358. VBIBacSub33497_2421.
Phylogenomic databases
OMA	AYLNFGH.
Family and domain databases
HAMAP	MF_00110. DHQ_synthase. [Tree]
InterPro	IPR016037. DHQ_synth_AroB. [Graphical view]
PIRSF	PIRSF001455. DHQ_synth. 1 hit.
TIGRFAMs	TIGR01357. AroB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A3F3F2_BACSU

Accession

Primary (citable) accession number: A3F3F2

Entry history

Integrated into UniProtKB/TrEMBL:	December 16, 2008
Last sequence update:	December 16, 2008
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)