A3DNJ8 (A3DNJ8_STAMF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981

Gene names

Ordered Locus Names:

Smar_1112

Organism

Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) [Complete proteome] [HAMAP]

Taxonomic identifier

399550 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Staphylothermus

Protein attributes

Sequence length	370 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. RuleBase RU003981
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981
Sequence similarities	Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase RuleBase RU003981 Methyltransferase EMBL ABN70208.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3DNJ8 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: FB8CA0191EB4F377	FASTA	370	42,405
	10 20 30 40 50 60 MAKIPLLNYH VEKLGAEPGF FGDWEVPMRY TSTIEEHLAV RSDVGVFDVS HMGRVRLRGP 70 80 90 100 110 120 DVFELIQYIY TKDLSKVKPG WMSGPTLALN QWARVKDDEM LYKISDEEWL LVPNALVREK 130 140 150 160 170 180 MLSYLKSIID SHQYKVVIED LTHKYSMIAV QGPKSPNIME KIGLKEAADL KPLQFITNIK 190 200 210 220 230 240 LNDIKLFLVS RSGWTGEDGF EIWGEHSSIA KLLDILVKEG VKPAGIIARD TLRMEMGFVL 250 260 270 280 290 300 GDHEYGEDPT KYPCVISLRY GLGAITWSKK GYVGEEALRA YLREGVRWIR MGIKMSKKNA 310 320 330 340 350 360 RIIPREHTPV YVEDQVVGWV TSGTYSPILR RGIAQAYIDV RYAIEDLPVK IMMRNRFYEG 370 KIVDFPFINK

References

[1]

"Complete genome sequence of Staphylothermus marinus Stetter and Fiala 1986 type strain F1." Anderson I.J., Sun H., Lapidus A., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Lucas S., Barry K., Land M., Richardson P., Huber H., Kyrpides N.C. Stand. Genomic Sci. 1:183-188(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The complete genome sequence of Staphylothermus marinus reveals differences in sulfur metabolism among heterotrophic Crenarchaeota." Anderson I.J., Dharmarajan L., Rodriguez J., Hooper S., Porat I., Ulrich L.E., Elkins J.G., Mavromatis K., Sun H., Land M., Lapidus A., Lucas S., Barry K., Huber H., Zhulin I.B., Whitman W.B., Mukhopadhyay B., Woese C., Bristow J., Kyrpides N. BMC Genomics 10:145-145(2009) [PubMed: 19341479] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000575 Genomic DNA. Translation: ABN70208.1.
RefSeq	YP_001041116.1. NC_009033.1.
3D structure databases
ProteinModelPortal	A3DNJ8.
ModBase	Search...
Protein-protein interaction databases
STRING	A3DNJ8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4907992.
GenomeReviews	Gene locus Smar_1112 in contig CP000575_GR.
KEGG	smr:Smar_1112.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG06551.
HOGENOM	HBG299834.
OMA	KALYGGM.
ProtClustDB	PRK00389.
Enzyme and pathway databases
BioCyc	SMAR399550:SMAR_1112-MONOMER.
Family and domain databases
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A3DNJ8_STAMF

Accession

Primary (citable) accession number: A3DNJ8

Entry history

Integrated into UniProtKB/TrEMBL:	March 20, 2007
Last sequence update:	March 20, 2007
Last modified:	November 16, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)