A3DLD3 (A3DLD3_STAMF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase HAMAP MF_00114
Short name=DERA HAMAP MF_00114
EC=4.1.2.4 HAMAP MF_00114

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase HAMAP MF_00114
Phosphodeoxyriboaldolase HAMAP MF_00114

Gene names

Name:	deoC HAMAP MF_00114
Ordered Locus Names:	Smar_0331

Organism

Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) [Complete proteome] [HAMAP]

Taxonomic identifier

399550 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Staphylothermus

Protein attributes

Sequence length	235 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity HAMAP MF_00114.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. HAMAP MF_00114

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00114
Ligand	Schiff base HAMAP MF_00114
Molecular function	Lyase HAMAP MF_00114 EMBL ABN69443.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	165	1	Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00114
	Active site	194	1	By similarity HAMAP MF_00114

Sequences

	Sequence		Length	Mass (Da)
	A3DLD3 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 053C2BC1242CD9F2	FASTA	235	25,418
	10 20 30 40 50 60 MGVGSLVEKL SVKEFASMID HTLLKPYADY KLLEKYVEDT RRYGFAVLML PPSLLLKARE 70 80 90 100 110 120 IAGNTIRLAT VIGFPLGNTF AGAKVLETRL AAQAGASEVD MVMNINYFKS GDYDRVLDDM 130 140 150 160 170 180 KHVVLEARKN NIGVVKVIIE TGLLSDEEKV KATELVVESG ADYVKTSTGF LAGGATIHDV 190 200 210 220 230 ALLYRVAKGR IKVKAAGGIR HALDALAMID AGASRIGTST GDKIIEEFIK LKEGK

References

[1]

"Complete genome sequence of Staphylothermus marinus Stetter and Fiala 1986 type strain F1." Anderson I.J., Sun H., Lapidus A., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Lucas S., Barry K., Land M., Richardson P., Huber H., Kyrpides N.C. Stand. Genomic Sci. 1:183-188(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The complete genome sequence of Staphylothermus marinus reveals differences in sulfur metabolism among heterotrophic Crenarchaeota." Anderson I.J., Dharmarajan L., Rodriguez J., Hooper S., Porat I., Ulrich L.E., Elkins J.G., Mavromatis K., Sun H., Land M., Lapidus A., Lucas S., Barry K., Huber H., Zhulin I.B., Whitman W.B., Mukhopadhyay B., Woese C., Bristow J., Kyrpides N. BMC Genomics 10:145-145(2009) [PubMed: 19341479] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000575 Genomic DNA. Translation: ABN69443.1.
RefSeq	YP_001040351.1. NC_009033.1.
3D structure databases
ProteinModelPortal	A3DLD3.
ModBase	Search...
Protein-protein interaction databases
STRING	A3DLD3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4907111.
GenomeReviews	Gene locus Smar_0331 in contig CP000575_GR.
KEGG	smr:Smar_0331.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG10952.
HOGENOM	HBG636421.
OMA	IDHTNLK.
PhylomeDB	A3DLD3.
ProtClustDB	CLSK2399472.
Enzyme and pathway databases
BioCyc	SMAR399550:SMAR_0331-MONOMER.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR022979. Deoxyribose_phosphate_aldo_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A3DLD3_STAMF

Accession

Primary (citable) accession number: A3DLD3

Entry history

Integrated into UniProtKB/TrEMBL:	March 20, 2007
Last sequence update:	March 20, 2007
Last modified:	November 16, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)