A3DKY1 (A3DKY1_STAMF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydroxymethylglutaryl-CoA reductase, degradative EMBL ABN69291.1
EC=1.1.1.88 EMBL ABN69291.1

Gene names

Ordered Locus Names:

Smar_0178

Organism

Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) [Complete proteome] [HAMAP]

Taxonomic identifier

399550 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Staphylothermus

Protein attributes

Sequence length	429 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ABN69291.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3DKY1 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 231E99AFC307315C	FASTA	429	46,974
	10 20 30 40 50 60 MSHETTRSSR IPGFYKKSLD ERLRIVAEWT GLTEEEINLL RNLGNLPEKI ADSMIENVIG 70 80 90 100 110 120 GMTYPFAVAV NFKINGKDYL VPMVIEETSV VAAASNAAKM LRRGKGIIAR AGPQEMIGQI 130 140 150 160 170 180 HLVNIEAPYY KSMKILEHKE EIIDHAKQQD STLLKLGGGP RDLEVRVLNT RIGPVIVVHL 190 200 210 220 230 240 IVDVLDAMGA NAVNTMVESI APLLEKITGG EARLRIISNY ATRRIVRAWV RTDPEDVGGK 250 260 270 280 290 300 DIARKIVEAS ILAEADPYRA VTHNKGIMNG IIAVALATAQ DHRAIEAGAH AYASRSGVYK 310 320 330 340 350 360 PLSTWELDEE EMLVGSLELP LQVGIVGGAT KVHPIAKIAL KILGVKTAKE LAEVMAAVGL 370 380 390 400 410 420 AQNLAALRAL VHEGIQKGHM RLHARNLAIM AGATGELIDK IAERMISEGR IRYDYAKKLL EEYLKGEYK

References

[1]

"Complete genome sequence of Staphylothermus marinus Stetter and Fiala 1986 type strain F1." Anderson I.J., Sun H., Lapidus A., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Lucas S., Barry K., Land M., Richardson P., Huber H., Kyrpides N.C. Stand. Genomic Sci. 1:183-188(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The complete genome sequence of Staphylothermus marinus reveals differences in sulfur metabolism among heterotrophic Crenarchaeota." Anderson I.J., Dharmarajan L., Rodriguez J., Hooper S., Porat I., Ulrich L.E., Elkins J.G., Mavromatis K., Sun H., Land M., Lapidus A., Lucas S., Barry K., Huber H., Zhulin I.B., Whitman W.B., Mukhopadhyay B., Woese C., Bristow J., Kyrpides N. BMC Genomics 10:145-145(2009) [PubMed: 19341479] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000575 Genomic DNA. Translation: ABN69291.1.
RefSeq	YP_001040199.1. NC_009033.1.
3D structure databases
ProteinModelPortal	A3DKY1.
SMR	A3DKY1. Positions 8-423.
ModBase	Search...
Protein-protein interaction databases
STRING	A3DKY1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4907940.
GenomeReviews	Gene locus Smar_0178 in contig CP000575_GR.
KEGG	smr:Smar_0178.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04678.
HOGENOM	HBG477902.
OMA	NNKGIMN.
ProtClustDB	CLSK731318.
Enzyme and pathway databases
BioCyc	SMAR399550:SMAR_0178-MONOMER.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR023076. HMG_CoA_Rdtase_CS. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
PANTHER	PTHR10572. HMG-CoA_red. 1 hit.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
PRINTS	PR00071. HMGCOARDTASE.
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS00318. HMG_COA_REDUCTASE_2. 1 hit. PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A3DKY1_STAMF

Accession

Primary (citable) accession number: A3DKY1

Entry history

Integrated into UniProtKB/TrEMBL:	March 20, 2007
Last sequence update:	March 20, 2007
Last modified:	November 16, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)