Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A3DJ77

- GUNC_CLOTH

UniProt

A3DJ77 - GUNC_CLOTH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Endoglucanase C

Gene

celC

Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.By similarity

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei140 – 1401Proton donorBy similarity
Active sitei280 – 2801NucleophileBy similarity

GO - Molecular functioni

  1. cellulase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

BioCyciCTHE203119:GIW8-2909-MONOMER.
UniPathwayiUPA00696.

Protein family/group databases

CAZyiGH5. Glycoside Hydrolase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase C (EC:3.2.1.4)
Alternative name(s):
Cellulase C
Endo-1,4-beta-glucanase C
Short name:
EgC
Gene namesi
Name:celC
Ordered Locus Names:Cthe_2807
OrganismiClostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)
Taxonomic identifieri203119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium
ProteomesiUP000002145: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 343343Endoglucanase CPRO_0000284720Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi203119.Cthe_2807.

Structurei

3D structure databases

ProteinModelPortaliA3DJ77.
SMRiA3DJ77. Positions 1-340.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2730.
HOGENOMiHOG000069582.
OMAiCNEFGVY.
OrthoDBiEOG6NPM7N.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
PROSITEiPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3DJ77-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVSFKAGINL GGWISQYQVF SKEHFDTFIT EKDIETIAEA GFDHVRLPFD
60 70 80 90 100
YPIIESDDNV GEYKEDGLSY IDRCLEWCKK YNLGLVLDMH HAPGYRFQDF
110 120 130 140 150
KTSTLFEDPN QQKRFVDIWR FLAKRYINER EHIAFELLNE VVEPDSTRWN
160 170 180 190 200
KLMLECVKAI REIDSTRWLY IGGNNYNSPD ELKNLADIDD DYIVYNFHFY
210 220 230 240 250
NPFFFTHQKA HWSESAMAYN RTVKYPGQYE GIEEFVKNNP KYSFMMELNN
260 270 280 290 300
LKLNKELLRK DLKPAIEFRE KKKCKLYCGE FGVIAIADLE SRIKWHEDYI
310 320 330 340
SLLEEYDIGG AVWNYKKMDF EIYNEDRKPV SQELVNILAR RKT
Length:343
Mass (Da):40,905
Last modified:March 20, 2007 - v1
Checksum:i72DD9BEA01A0DD05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN54006.1.
RefSeqiYP_001039199.1. NC_009012.1.

Genome annotation databases

EnsemblBacteriaiABN54006; ABN54006; Cthe_2807.
GeneIDi4809644.
KEGGicth:Cthe_2807.
PATRICi19519672. VBICloThe47081_2989.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN54006.1 .
RefSeqi YP_001039199.1. NC_009012.1.

3D structure databases

ProteinModelPortali A3DJ77.
SMRi A3DJ77. Positions 1-340.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 203119.Cthe_2807.

Protein family/group databases

CAZyi GH5. Glycoside Hydrolase Family 5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABN54006 ; ABN54006 ; Cthe_2807 .
GeneIDi 4809644.
KEGGi cth:Cthe_2807.
PATRICi 19519672. VBICloThe47081_2989.

Phylogenomic databases

eggNOGi COG2730.
HOGENOMi HOG000069582.
OMAi CNEFGVY.
OrthoDBi EOG6NPM7N.

Enzyme and pathway databases

UniPathwayi UPA00696 .
BioCyci CTHE203119:GIW8-2909-MONOMER.

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
InterProi IPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF00150. Cellulase. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 2 hits.
PROSITEi PS00659. GLYCOSYL_HYDROL_F5. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372.

Entry informationi

Entry nameiGUNC_CLOTH
AccessioniPrimary (citable) accession number: A3DJ77
Secondary accession number(s): P07985
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: March 20, 2007
Last modified: October 1, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3