Methyltransferase type 12 - Clostridium thermocellum (strain ATCC 27405 / DSM 1237)

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A3DJ37 (A3DJ37_CLOTH) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 38. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

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Names·Attributes·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Methyltransferase type 12 EMBL ABN53966.1

Gene names

Ordered Locus Names:

Cthe_2767

Organism

Clostridium thermocellum (strain ATCC 27405 / DSM 1237) [Complete proteome] [HAMAP] EMBL ABN53966.1

Taxonomic identifier

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium ›

Protein attributes

Sequence length	465 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Methyltransferase EMBL ABN53966.1 Transferase
Technical term	3D-structure PDB 3JWI PDB 3JWG PDB 4DQZ PDB 4DRF PDB 4E6N Complete proteome
Gene Ontology (GO)
Molecular_function	O-methyltransferase activity Inferred from electronic annotation. Source: InterPro RNA methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

A3DJ37 [UniParc].

Last modified March 20, 2007. Version 1.
Checksum: 6BAD46C5FAA7D220
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465

53,576

        10         20         30         40         50         60 
MILTITYTQP PATDLGYLLH KNPSRPQTFE LNHGKAHIFY PEATSERCTV ALLLDIDPID 

        70         80         90        100        110        120 
LARGKKGSSG EGGLFDYVND RPYVSSSFMS VAISRVFGTA MSGKCKEKPE LAAIKLPLKA 

       130        140        150        160        170        180 
KIMMLPCKGG EEIIYRLFEP LGYKVDVEGY MLDEKFPEWG KSRYYTVSLE GEVRVRDLLN 

       190        200        210        220        230        240 
HIYVLIPVLD SEKHYWVGED EIDKLFQHGE GWLVDHPEKE LITGRYLIRK KRLVNQALKR 

       250        260        270        280        290        300 
LLEASDVVDD ENEDDEPLKN EETEKKLNLN QQRLGTVVAV LKSVNAKKVI DLGCGEGNLL 

       310        320        330        340        350        360 
SLLLKDKSFE QITGVDVSYS VLERAKDRLK IDRLPEMQRK RISLFQSSLV YRDKRFSGYD 

       370        380        390        400        410        420 
AATVIEVIEH LDENRLQAFE KVLFEFTRPQ TVIVSTPNKE YNFHYQNLFE GNLRHRDHRF 

       430        440        450        460 
EWTRKEFETW AVKVAEKYGY SVRFLQIGEI DDEFGSPTQM GVFTL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequence of Clostridium thermocellum ATCC 27405." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. Richardson P. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27405 / DSM 1237.
[2]	"Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1." Mui Chan C., Zhou C., Brunzelle J.S., Huang R.H. Proc. Natl. Acad. Sci. U.S.A. 106:17699-17704(2009) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 258-465.
[3]	"Molecular basis of bacterial protein Hen1 activating the ligase activity of bacterial protein Pnkp for RNA repair." Wang P., Chan C.M., Christensen D., Zhang C., Selvadurai K., Huang R.H. Proc. Natl. Acad. Sci. U.S.A. 109:13248-13253(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 1-230.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000568 Genomic DNA. Translation: ABN53966.1.

RefSeq

YP_001039159.1. NC_009012.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3JWG	X-ray	1.90	A	258-465	[»]
3JWI	X-ray	2.20	A/B	259-465	[»]
4DQZ	X-ray	2.30	A/B	1-230	[»]
4DRF	X-ray	2.60	B/D	1-230	[»]
4E6N	X-ray	2.39	B/D	1-230	[»]

ProteinModelPortal

ModBase

Protein-protein interaction databases

STRING

203119.Cthe_2767.

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

ABN53966; ABN53966; Cthe_2767.

GeneID

KEGG

PATRIC

19519586. VBICloThe47081_2946.

Organism-specific databases

CMR

Phylogenomic databases

eggNOG

HOGENOM

OMA

ProtClustDB

Enzyme and pathway databases

BioCyc

CTHE203119:GIW8-2868-MONOMER.

Family and domain databases

InterPro

IPR024026. 3'-RNA_MeTfrase_Hen1_bac.
IPR026610. Hen1.
IPR024740. Hen1_N.
[Graphical view]

PANTHER

PTHR21404. PTHR21404. 1 hit.

Pfam

PF12623. Hen1_L. 1 hit.
[Graphical view]

TIGRFAMs

TIGR04074. bacter_Hen1. 1 hit.

ProtoNet

Other

EvolutionaryTrace

Entry information

Entry name

A3DJ37_CLOTH

Accession

Primary (citable) accession number: A3DJ37

Entry history

Integrated into UniProtKB/TrEMBL:	March 20, 2007
Last sequence update:	March 20, 2007
Last modified:	May 1, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

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Names·Attributes·Ontologies·Sequences·References·Cross-refs·Entry info