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A3DFP1 (A3DFP1_CLOTH) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aspartate--tRNA ligase 2 HAMAP MF_00044
EC=6.1.1.12 HAMAP MF_00044
Alternative name(s):
Aspartyl-tRNA synthetase 2 HAMAP MF_00044
Gene names
Name:aspS2 HAMAP MF_00044
Ordered Locus Names:Cthe_1543
OrganismClostridium thermocellum (strain ATCC 27405 / DSM 1237) [Complete proteome] [HAMAP]
Taxonomic identifier203119 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length581 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). HAMAP MF_00044

Subunit structure

Homodimer By similarity. HAMAP MF_00044

Subcellular location

Cytoplasm By similarity HAMAP MF_00044.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP MF_00044

Sequences

Sequence LengthMass (Da)Tools
A3DFP1 [UniParc].

Last modified March 20, 2007. Version 1.
Checksum: 8C5DB531DDF7D5BD

FASTA58166,497
        10         20         30         40         50         60 
MAEIYRTKTM NQITEEDIGS VLKIAGWVEN IRDHGGVSFI DLRDMYGVMQ VVFRNIEFPK 

        70         80         90        100        110        120 
GIRKEECLSI EGVIEKRDEE TYNPKIPTGT IELVAQKVTV LGRVYRDLPF EVATSKEIRE 

       130        140        150        160        170        180 
EVRLKYRYLD LRNRKVKDNI LFRSQVISFL RQKMTEMGFV EIQTPILSAS SPEGARDYIV 

       190        200        210        220        230        240 
PSRKHKGKFY ALPQAPQIYK QLLMVSGFDK YFQIAPCFRD EDARADRSPG EFYQLDFEMS 

       250        260        270        280        290        300 
FATQEDVFRV GEEVLTATFK KFAPEGYEIT EAPFPVFSYK QAMLEFGTDK PDLRNPLRII 

       310        320        330        340        350        360 
DVTDFFQRCA FKPFHNKTVR AIKVHADMSK GFHEKLLEYA LSIGMGGLGY LEVQEDMTYK 

       370        380        390        400        410        420 
GPIDKYIPQE LKGELAQISG LIPGDVIFFI ADKEKLACKY AGLIRNELGK RLDICEKNAY 

       430        440        450        460        470        480 
RFCYVNDFPM YEMDEETGKI EFTHNPFSMP QGGLEALNTK GPLDILAYQY DIVCNGVELS 

       490        500        510        520        530        540 
SGAVRNHDLD IMVKAFEIAG YDEETLKKKF GALYNAFQYG APPHAGMAPG IERMIMLLRN 

       550        560        570        580 
EENIREVVAF PMNSNAQDLL CGAPGEVTEQ QLREVHIKIR N

« Hide

References

[1]"Complete sequence of Clostridium thermocellum ATCC 27405."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D., Newcomb M., Richardson P.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27405 / DSM 1237.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000568 Genomic DNA. Translation: ABN52770.1.
RefSeqYP_001037963.1. NC_009012.1.

3D structure databases

ProteinModelPortalA3DFP1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3DFP1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4810050.
GenomeReviewsGene locus Cthe_1543 in contig CP000568_GR.
KEGGcth:Cthe_1543.
NMPDRfig|203119.1.peg.3364.
PATRIC19516913. VBICloThe47081_1636.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0173.
HOGENOMHBG396032.
OMAYQLDVEM.
ProtClustDBCLSK2534226.

Family and domain databases

HAMAPMF_00044_B. Asp_tRNA_synth_B.
[Tree]
InterProIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004524. Asp-tRNA-synth_IIb_bac/mt.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR004115. GAD_dom.
IPR012340. NA-bd_OB-fold.
IPR016027. NA-bd_OB-fold-like.
IPR004365. NA-bd_OB_tRNA-helicase.
[Graphical view]
Gene3DG3DSA:3.30.1360.30. GAD_dom. 1 hit.
G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KOK01876.
PANTHERPTHR22594. aa-tRNA-synt_II. 1 hit.
PTHR22594:SF5. AspS_bac. 1 hit.
PfamPF02938. GAD. 1 hit.
PF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
PRINTSPR01042. TRNASYNTHASP.
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
SSF55261. SSF55261. 1 hit.
TIGRFAMsTIGR00459. AspS_bact. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3DFP1_CLOTH
AccessionPrimary (citable) accession number: A3DFP1
Entry history
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info