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A3DEM3 (A3DEM3_CLOTH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydrodipicolinate reductase 2 HAMAP MF_00102
Short name=DHPR 2 HAMAP MF_00102
EC=1.3.1.26 HAMAP MF_00102
Gene names
Name:dapB2 HAMAP MF_00102
Ordered Locus Names:Cthe_1170
OrganismClostridium thermocellum (strain ATCC 27405 / DSM 1237) [Complete proteome] [HAMAP]
Taxonomic identifier203119 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length291 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102

Subcellular location

Cytoplasm By similarity HAMAP MF_00102.

Sequence similarities

Belongs to the dihydrodipicolinate reductase family. HAMAP MF_00102

Sequences

Sequence LengthMass (Da)Tools
A3DEM3 [UniParc].

Last modified March 20, 2007. Version 1.
Checksum: 914C769C856B05D3

FASTA29132,289
        10         20         30         40         50         60 
MIRVCLVGLG KTGKEIAKVI LEQENMKLVS VVCSSKSQNL GKSLDEIIGC RNSGIIVDSE 

        70         80         90        100        110        120 
KNLEQVIFKT KPDVVVDFST PDATIRNAKI FSKMKVNIVV GTTGFTDFAL KKLFVLTRKY 

       130        140        150        160        170        180 
HNAICYAPNI TLGVNVLMLL TNLAASILNN YDFQITEIHH KRKVDVPSGT AIKIAGEIKK 

       190        200        210        220        230        240 
GLDSAGVSIK EKVIPINAVR AGGVVGRHEV MIVGEDDKIE ISHESFSRRA FALGAIKAIE 

       250        260        270        280        290 
FIHDKVGYYE MSDVLNLHKV LEDYIEKEQI KRKKKYKKCR NDVEESPVSV V

« Hide

References

[1]"Complete sequence of Clostridium thermocellum ATCC 27405."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D., Newcomb M., Richardson P.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27405 / DSM 1237.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000568 Genomic DNA. Translation: ABN52402.1.
RefSeqYP_001037595.1. NC_009012.1.

3D structure databases

ProteinModelPortalA3DEM3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3DEM3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4810122.
GenomeReviewsGene locus Cthe_1170 in contig CP000568_GR.
KEGGcth:Cthe_1170.
NMPDRfig|203119.1.peg.71.
PATRIC19516095. VBICloThe47081_1229.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0289.
HOGENOMHBG594002.
OMAEISHESF.
ProtClustDBCLSK965049.

Family and domain databases

HAMAPMF_00102. DapB.
[Tree]
InterProIPR022663. DapB_C.
IPR000846. DapB_N.
IPR011770. Dihydrodipicolinate_Rdtase.
IPR023940. Dihydrodipicolinate_Rdtase_bac.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00215.
PANTHERPTHR20836. DapB_bac/pln. 1 hit.
PfamPF05173. DapB_C. 1 hit.
PF01113. DapB_N. 1 hit.
[Graphical view]
PIRSFPIRSF000161. DHPR. 1 hit.
TIGRFAMsTIGR00036. DapB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA3DEM3_CLOTH
AccessionPrimary (citable) accession number: A3DEM3
Entry history
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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