A3DDQ9 (A3DDQ9_CLOTH) Unreviewed, UniProtKB/TrEMBL
Last modified
December 14, 2011.
Version 46.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Shikimate dehydrogenase HAMAP MF_00222 EC=1.1.1.25 HAMAP MF_00222 | ||||
| Gene names |
| ||||
| Organism | Clostridium thermocellum (strain ATCC 27405 / DSM 1237) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 203119 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium |
Protein attributes
| Sequence length | 298 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | Shikimate + NADP+ = 3-dehydroshikimate + NADPH. SAAS SAAS011342 HAMAP MF_00222 |
| Pathway | Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222 SAAS SAAS011342 |
| Sequence similarities | Belongs to the shikimate dehydrogenase family. HAMAP MF_00222 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis SAAS SAAS011342 HAMAP MF_00222 |
| Ligand | NADP SAAS SAAS011342 HAMAP MF_00222 |
| Molecular function | Oxidoreductase SAAS SAAS011342 HAMAP MF_00222 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Molecular function | NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Regions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Nucleotide binding | 136 – 140 | 5 | NADP By similarity HAMAP MF_00222 | ||||||
Sites | |||||||||
| Active site | 75 | 1 | Proton acceptor By similarity HAMAP MF_00222 | ||||||
Sequences
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References
| [1] | "Complete sequence of Clostridium thermocellum ATCC 27405." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. Richardson P.Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27405 / DSM 1237. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000568 Genomic DNA. Translation: ABN52088.1. |
| RefSeq | YP_001037281.1. NC_009012.1. |
3D structure databases | |
| ProteinModelPortal | A3DDQ9. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A3DDQ9. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 4810472. |
| GenomeReviews | Gene locus Cthe_0854 in contig CP000568_GR. |
| KEGG | cth:Cthe_0854. |
| NMPDR | fig|203119.1.peg.269. |
| PATRIC | 19515419. VBICloThe47081_0898. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0169. |
| HOGENOM | HBG553408. |
| OMA | FANATIV. |
| ProtClustDB | CLSK2471724. |
Family and domain databases | |
| HAMAP | MF_00222. Shikimate_DH_AroE. [Tree] |
| InterPro | IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| KO | K00014. |
| Pfam | PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00507. AroE. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | A3DDQ9_CLOTH | ||||||||
| Accession | Primary (citable) accession number: A3DDQ9 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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