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Protein
Submitted name:

Lipolytic protein G-D-S-L family

Gene

Cthe_0798

Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi73 – 731CalciumCombined sources
Metal bindingi74 – 741Calcium; via carbonyl oxygenCombined sources
Metal bindingi87 – 871CalciumCombined sources
Metal bindingi89 – 891CalciumCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

CalciumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BioCyciCTHE203119:GIW8-826-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Lipolytic protein G-D-S-L familyImported
Gene namesi
Ordered Locus Names:Cthe_0798Imported
OrganismiClostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)Imported
Taxonomic identifieri203119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium
Proteomesi
  • UP000002145 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131Sequence analysisAdd
BLAST
Chaini32 – 528497Sequence analysisPRO_5002651657Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi203119.Cthe_0798.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2VPTX-ray1.40A32-237[»]
ProteinModelPortaliA3DDK4.
SMRiA3DDK4. Positions 34-234, 250-450.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA3DDK4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini466 – 52863DockerinInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108N22. Bacteria.
ENOG4110Y6E. LUCA.
OMAiKIARIWF.
OrthoDBiEOG6WMHTW.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
3.40.50.1110. 2 hits.
InterProiIPR002105. Dockerin_1_rpt.
IPR016134. Dockerin_dom.
IPR013830. SGNH_hydro.
[Graphical view]
PfamiPF00404. Dockerin_1. 2 hits.
PF13472. Lipase_GDSL_2. 2 hits.
[Graphical view]
SUPFAMiSSF52266. SSF52266. 2 hits.
SSF63446. SSF63446. 1 hit.
PROSITEiPS00448. CLOS_CELLULOSOME_RPT. 2 hits.
PS51766. DOCKERIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3DDK4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKSKNLAAK VLSTLLIFIT VISLINMEAP AASKTIKIMP VGDSCTEGMG
60 70 80 90 100
GGEMGSYRTE LYRLLTQAGL SIDFVGSQRS GPSSLPDKDH EGHSGWTIPQ
110 120 130 140 150
IASNINNWLN THNPDVVFLW IGGNDLLLNG NLNATGLSNL IDQIFTVKPN
160 170 180 190 200
VTLFVADYYP WPEAIKQYNA VIPGIVQQKA NAGKKVYFVK LSEIQFDRNT
210 220 230 240 250
DISWDGLHLS EIGYKKIANI WYKYTIDILR ALAGETQPNP SPSSTPNTTK
260 270 280 290 300
TIKIMPVGDS CTEGMGGGEM GSYRTELYRL LTQAGLSIDF VGSQRSGPSS
310 320 330 340 350
LPDKDHEGHS GWTIPQIASN INNWLNTHNP DVVFLWIGGN DLLLSGNVNA
360 370 380 390 400
TGLSNLIDQI FTVKPNVTLF VADYYPWPEA VKQYNAVIPG IVQQKANAGK
410 420 430 440 450
KVYFVKLSEI QFDRNTDISW DGLHLSEIGY TKIANIWYKY TIDILKALAG
460 470 480 490 500
QTQPTPSPSP TPTDSPLVKK GDVNLDGQVN STDFSLLKRY ILKVVDINSI
510 520
NVTNADMNND GNINSTDISI LKRILLRN
Length:528
Mass (Da):58,073
Last modified:March 20, 2007 - v1
Checksum:i8A25788A79D345FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN52033.1.
RefSeqiWP_011837904.1. NC_009012.1.

Genome annotation databases

EnsemblBacteriaiABN52033; ABN52033; Cthe_0798.
KEGGicth:Cthe_0798.
PATRICi19515301. VBICloThe47081_0839.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN52033.1.
RefSeqiWP_011837904.1. NC_009012.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2VPTX-ray1.40A32-237[»]
ProteinModelPortaliA3DDK4.
SMRiA3DDK4. Positions 34-234, 250-450.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203119.Cthe_0798.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN52033; ABN52033; Cthe_0798.
KEGGicth:Cthe_0798.
PATRICi19515301. VBICloThe47081_0839.

Phylogenomic databases

eggNOGiENOG4108N22. Bacteria.
ENOG4110Y6E. LUCA.
OMAiKIARIWF.
OrthoDBiEOG6WMHTW.

Enzyme and pathway databases

BioCyciCTHE203119:GIW8-826-MONOMER.

Miscellaneous databases

EvolutionaryTraceiA3DDK4.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
3.40.50.1110. 2 hits.
InterProiIPR002105. Dockerin_1_rpt.
IPR016134. Dockerin_dom.
IPR013830. SGNH_hydro.
[Graphical view]
PfamiPF00404. Dockerin_1. 2 hits.
PF13472. Lipase_GDSL_2. 2 hits.
[Graphical view]
SUPFAMiSSF52266. SSF52266. 2 hits.
SSF63446. SSF63446. 1 hit.
PROSITEiPS00448. CLOS_CELLULOSOME_RPT. 2 hits.
PS51766. DOCKERIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372Imported.
  2. "Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides insights into the mechanism of substrate recognition."
    Correia M.A., Prates J.A., Bras J., Fontes C.M., Newman J.A., Lewis R.J., Gilbert H.J., Flint J.E.
    J. Mol. Biol. 379:64-72(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS) OF 32-237 IN COMPLEX WITH CALCIUM.

Entry informationi

Entry nameiA3DDK4_CLOTH
AccessioniPrimary (citable) accession number: A3DDK4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: April 13, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.