Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chorismate mutase AroH

Gene

Cthe_0711

Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.UniRule annotation

Catalytic activityi

Chorismate = prephenate.UniRule annotation

Pathwayi: prephenate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes prephenate from chorismate.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Chorismate mutase AroH (Cthe_0711)
This subpathway is part of the pathway prephenate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes prephenate from chorismate, the pathway prephenate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei6 – 61SubstrateUniRule annotation
Binding sitei88 – 881SubstrateUniRule annotation
Binding sitei106 – 1061SubstrateUniRule annotation
Binding sitei114 – 1141SubstrateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciCTHE203119:GIW8-738-MONOMER.
UniPathwayiUPA00120; UER00203.

Names & Taxonomyi

Protein namesi
Recommended name:
Chorismate mutase AroHUniRule annotation (EC:5.4.99.5UniRule annotation)
Gene namesi
Ordered Locus Names:Cthe_0711Imported
OrganismiClostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)Imported
Taxonomic identifieri203119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium
Proteomesi
  • UP000002145 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi203119.Cthe_0711.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1XHOX-ray2.20A/B/C1-118[»]
ProteinModelPortaliA3DDB7.
SMRiA3DDB7. Positions 1-113.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA3DDB7.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105KHN. Bacteria.
COG4401. LUCA.
HOGENOMiHOG000043606.
KOiK06208.
OMAiCIRVMMT.
OrthoDBiPOG091H0FMF.

Family and domain databases

Gene3Di3.30.1330.40. 1 hit.
InterProiIPR008243. Chorismate_mutase_AroH.
IPR013813. Endoribo_LPSP/chorism_mut-like.
[Graphical view]
PANTHERiPTHR21164. PTHR21164. 1 hit.
PfamiPF07736. CM_1. 1 hit.
[Graphical view]
PIRSFiPIRSF005965. Chor_mut_AroH. 1 hit.
ProDomiPD031888. Chorismate_mutase_AroH. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF55298. SSF55298. 1 hit.
TIGRFAMsiTIGR01796. CM_mono_aroH. 1 hit.
PROSITEiPS51167. CHORISMATE_MUT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3DDB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVWAIRGATT VSDNTADEIV AETQKLLKEM AEKNGLEEDD IISIIFTVTK
60 70 80 90 100
DLDAAFPAIA ARNMGWTSTA LMCMNEIDVP GSLEKCIRVM MHVNTDKDKK
110
DIKHVYLNGA KVLRPDLT
Length:118
Mass (Da):13,096
Last modified:March 20, 2007 - v1
Checksum:iE015FF82080E3EB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN51946.1.
RefSeqiWP_003516211.1. NC_009012.1.

Genome annotation databases

EnsemblBacteriaiABN51946; ABN51946; Cthe_0711.
KEGGicth:Cthe_0711.
PATRICi19515119. VBICloThe47081_0748.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN51946.1.
RefSeqiWP_003516211.1. NC_009012.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1XHOX-ray2.20A/B/C1-118[»]
ProteinModelPortaliA3DDB7.
SMRiA3DDB7. Positions 1-113.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203119.Cthe_0711.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN51946; ABN51946; Cthe_0711.
KEGGicth:Cthe_0711.
PATRICi19515119. VBICloThe47081_0748.

Phylogenomic databases

eggNOGiENOG4105KHN. Bacteria.
COG4401. LUCA.
HOGENOMiHOG000043606.
KOiK06208.
OMAiCIRVMMT.
OrthoDBiPOG091H0FMF.

Enzyme and pathway databases

UniPathwayiUPA00120; UER00203.
BioCyciCTHE203119:GIW8-738-MONOMER.

Miscellaneous databases

EvolutionaryTraceiA3DDB7.

Family and domain databases

Gene3Di3.30.1330.40. 1 hit.
InterProiIPR008243. Chorismate_mutase_AroH.
IPR013813. Endoribo_LPSP/chorism_mut-like.
[Graphical view]
PANTHERiPTHR21164. PTHR21164. 1 hit.
PfamiPF07736. CM_1. 1 hit.
[Graphical view]
PIRSFiPIRSF005965. Chor_mut_AroH. 1 hit.
ProDomiPD031888. Chorismate_mutase_AroH. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF55298. SSF55298. 1 hit.
TIGRFAMsiTIGR01796. CM_mono_aroH. 1 hit.
PROSITEiPS51167. CHORISMATE_MUT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA3DDB7_CLOTH
AccessioniPrimary (citable) accession number: A3DDB7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: September 7, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.