Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chorismate mutase AroH

Gene

Cthe_0711

Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.UniRule annotation

Catalytic activityi

Chorismate = prephenate.UniRule annotation

Pathwayi: prephenate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes prephenate from chorismate.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Chorismate mutase AroH (Cthe_0711)
This subpathway is part of the pathway prephenate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes prephenate from chorismate, the pathway prephenate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei6SubstrateUniRule annotation1
Binding sitei88SubstrateUniRule annotation1
Binding sitei106SubstrateUniRule annotation1
Binding sitei114SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotation
Biological processAmino-acid biosynthesis, Aromatic amino acid biosynthesisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00120; UER00203.

Names & Taxonomyi

Protein namesi
Recommended name:
Chorismate mutase AroHUniRule annotation (EC:5.4.99.5UniRule annotation)
Gene namesi
Ordered Locus Names:Cthe_0711Imported
OrganismiClostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)Imported
Taxonomic identifieri203119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium
Proteomesi
  • UP000002145 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi203119.Cthe_0711.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XHOX-ray2.20A/B/C1-118[»]
ProteinModelPortaliA3DDB7.
SMRiA3DDB7.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA3DDB7.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105KHN. Bacteria.
COG4401. LUCA.
HOGENOMiHOG000043606.
KOiK06208.
OMAiCIRVMMT.
OrthoDBiPOG091H0FMF.

Family and domain databases

CDDicd02185. AroH. 1 hit.
Gene3Di3.30.1330.40. 1 hit.
InterProiView protein in InterPro
IPR008243. Chorismate_mutase_AroH.
IPR013813. Endoribo_LPSP/chorism_mut-like.
PANTHERiPTHR21164. PTHR21164. 1 hit.
PfamiView protein in Pfam
PF07736. CM_1. 1 hit.
PIRSFiPIRSF005965. Chor_mut_AroH. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD031888. Chorismate_mutase_AroH. 1 hit.
SUPFAMiSSF55298. SSF55298. 1 hit.
TIGRFAMsiTIGR01796. CM_mono_aroH. 1 hit.
PROSITEiView protein in PROSITE
PS51167. CHORISMATE_MUT_1. 1 hit.

Sequencei

Sequence statusi: Complete.

A3DDB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVWAIRGATT VSDNTADEIV AETQKLLKEM AEKNGLEEDD IISIIFTVTK
60 70 80 90 100
DLDAAFPAIA ARNMGWTSTA LMCMNEIDVP GSLEKCIRVM MHVNTDKDKK
110
DIKHVYLNGA KVLRPDLT
Length:118
Mass (Da):13,096
Last modified:March 20, 2007 - v1
Checksum:iE015FF82080E3EB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN51946.1.
RefSeqiWP_003516211.1. NC_009012.1.

Genome annotation databases

EnsemblBacteriaiABN51946; ABN51946; Cthe_0711.
KEGGicth:Cthe_0711.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA3DDB7_CLOTH
AccessioniPrimary (citable) accession number: A3DDB7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: July 5, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported