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Protein
Submitted name:

Ricin B lectin

Gene

Cthe_0661

Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei438GalactoseCombined sources1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Ligandi

LectinImported

Enzyme and pathway databases

BRENDAi3.2.1.145. 1530.

Protein family/group databases

CAZyiCBM13. Carbohydrate-Binding Module Family 13.
GH43. Glycoside Hydrolase Family 43.

Names & Taxonomyi

Protein namesi
Submitted name:
Ricin B lectinImported
Gene namesi
Ordered Locus Names:Cthe_0661Imported
OrganismiClostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)Imported
Taxonomic identifieri203119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium
Proteomesi
  • UP000002145 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_500265224832 – 571Sequence analysisAdd BLAST540

Interactioni

Protein-protein interaction databases

STRINGi203119.Cthe_0661.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3VSFX-ray2.76A/B/C/D/E/F31-520[»]
3VSZX-ray2.89A/B/C/D/E/F31-520[»]
3VT0X-ray2.91A/B/C/D/E/F31-520[»]
3VT1X-ray3.19A/B/C/D/E/F31-520[»]
3VT2X-ray3.00A/B/C/D/E/F31-520[»]
ProteinModelPortaliA3DD67.
SMRiA3DD67.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini353 – 491Ricin B-type lectinInterPro annotationAdd BLAST139
Domaini504 – 571DockerinInterPro annotationAdd BLAST68

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni416 – 420Galactose bindingCombined sources5
Regioni431 – 434Galactose bindingCombined sources4

Sequence similaritiesi

Belongs to the glycosyl hydrolase 43 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105DZZ. Bacteria.
ENOG410XS3S. LUCA.
HOGENOMiHOG000169275.
OMAiPNQAKYA.
OrthoDBiPOG091H0TAU.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.115.10.20. 1 hit.
InterProiIPR002105. Dockerin_1_rpt.
IPR016134. Dockerin_dom.
IPR018247. EF_Hand_1_Ca_BS.
IPR006710. Glyco_hydro_43.
IPR023296. Glyco_hydro_beta-prop.
IPR000772. Ricin_B_lectin.
[Graphical view]
PANTHERiPTHR22925. PTHR22925. 1 hit.
PfamiPF00404. Dockerin_1. 2 hits.
PF04616. Glyco_hydro_43. 1 hit.
PF14200. RicinB_lectin_2. 2 hits.
[Graphical view]
SMARTiSM00458. RICIN. 1 hit.
[Graphical view]
SUPFAMiSSF50370. SSF50370. 1 hit.
SSF63446. SSF63446. 1 hit.
SSF75005. SSF75005. 1 hit.
PROSITEiPS00448. CLOS_CELLULOSOME_RPT. 2 hits.
PS51766. DOCKERIN. 1 hit.
PS00018. EF_HAND_1. 1 hit.
PS50231. RICIN_B_LECTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A3DD67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKKNVGLRF LSILILMALL IGNVQSFNVA AAEGVIVNGT QFKDTSGNVI
60 70 80 90 100
HAHGGGMLKH GDYYYWYGEY RDDSNLFLGV SCYRSKDLVN WEYRGEVLSR
110 120 130 140 150
NSAPELNHCN IERPKVMYNA STGEFVMWMH WENGINYGQA RAAVAYSKTP
160 170 180 190 200
DGKFTYIRSF RPMQDTGVMD HGLPGYMSRD CNVFVDTDGK GYFISAANEN
210 220 230 240 250
MDLHLYELTP DYKNIASLKA KLFVGQQREA PCLIKRNGYY YLITSGCTGW
260 270 280 290 300
NPNQAKYAYS KDLASGWSQL YNLGNSTTYR SQPTFIIPVQ GSSGTSYLYM
310 320 330 340 350
GDRWAGAWGG KVNDSQYVWL PLNFISDTTL ELPYYDSVKI DASSGIISEY
360 370 380 390 400
IPDTTRYKLV NKNSGKVLDV LDGSVDNAAQ IVQWTDNGSL SQQWYLVDVG
410 420 430 440 450
GGYKKIVNVK SGRALDVKDE SKEDGGVLIQ YTSNGGYNQH WKFTDIGDGY
460 470 480 490 500
YKISSRHCGK LIDVRKWSTE DGGIIQQWSD AGGTNQHWKL VLVSSPEPSP
510 520 530 540 550
SPSPQVVKGD VNGDLKVNST DFSMLRRYLL KTIDNFPTEN GKQAADLNGD
560 570
GRINSSDLTM LKRYLLMEVD L
Length:571
Mass (Da):63,895
Last modified:March 20, 2007 - v1
Checksum:i5034D6F32BBA3CA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN51896.1.
RefSeqiWP_011837884.1. NC_009012.1.

Genome annotation databases

EnsemblBacteriaiABN51896; ABN51896; Cthe_0661.
KEGGicth:Cthe_0661.
PATRICi19515007. VBICloThe47081_0694.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN51896.1.
RefSeqiWP_011837884.1. NC_009012.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3VSFX-ray2.76A/B/C/D/E/F31-520[»]
3VSZX-ray2.89A/B/C/D/E/F31-520[»]
3VT0X-ray2.91A/B/C/D/E/F31-520[»]
3VT1X-ray3.19A/B/C/D/E/F31-520[»]
3VT2X-ray3.00A/B/C/D/E/F31-520[»]
ProteinModelPortaliA3DD67.
SMRiA3DD67.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203119.Cthe_0661.

Protein family/group databases

CAZyiCBM13. Carbohydrate-Binding Module Family 13.
GH43. Glycoside Hydrolase Family 43.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN51896; ABN51896; Cthe_0661.
KEGGicth:Cthe_0661.
PATRICi19515007. VBICloThe47081_0694.

Phylogenomic databases

eggNOGiENOG4105DZZ. Bacteria.
ENOG410XS3S. LUCA.
HOGENOMiHOG000169275.
OMAiPNQAKYA.
OrthoDBiPOG091H0TAU.

Enzyme and pathway databases

BRENDAi3.2.1.145. 1530.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.115.10.20. 1 hit.
InterProiIPR002105. Dockerin_1_rpt.
IPR016134. Dockerin_dom.
IPR018247. EF_Hand_1_Ca_BS.
IPR006710. Glyco_hydro_43.
IPR023296. Glyco_hydro_beta-prop.
IPR000772. Ricin_B_lectin.
[Graphical view]
PANTHERiPTHR22925. PTHR22925. 1 hit.
PfamiPF00404. Dockerin_1. 2 hits.
PF04616. Glyco_hydro_43. 1 hit.
PF14200. RicinB_lectin_2. 2 hits.
[Graphical view]
SMARTiSM00458. RICIN. 1 hit.
[Graphical view]
SUPFAMiSSF50370. SSF50370. 1 hit.
SSF63446. SSF63446. 1 hit.
SSF75005. SSF75005. 1 hit.
PROSITEiPS00448. CLOS_CELLULOSOME_RPT. 2 hits.
PS51766. DOCKERIN. 1 hit.
PS00018. EF_HAND_1. 1 hit.
PS50231. RICIN_B_LECTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA3DD67_CLOTH
AccessioniPrimary (citable) accession number: A3DD67
Entry historyi
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: November 2, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.