Skip Header

Contribute Send feedback
Read comments (?) or add your own

A3DD16 (A3DD16_CLOTH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase 1 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase 1 HAMAP MF_01023
Gene names
Name:hisC1 HAMAP MF_01023
Ordered Locus Names:Cthe_0610
OrganismClostridium thermocellum (strain ATCC 27405 / DSM 1237) [Complete proteome] [HAMAP]
Taxonomic identifier203119 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861

Subunit structure

Homodimer By similarity. HAMAP MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2101N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

Sequence LengthMass (Da)Tools
A3DD16 [UniParc].

Last modified March 20, 2007. Version 1.
Checksum: 7494E431B78366A4

FASTA35540,409
        10         20         30         40         50         60 
MSKYWSNIVK KISPYVPGEQ PKDKKYIKLN TNENPYPPSE KVLKAISAAV NESLRLYPDP 

        70         80         90        100        110        120 
ACESLRNTLA KYYGIKASEV FVGNGSDELL AFSFMAFFNP GDTIIFPDIT YSFYEVYSSM 

       130        140        150        160        170        180 
FSVNYRLIPL DDEFNVPVEE FFTENDGIIL ANPNAPTGKA LPLQSIRKIL EKNDDKVVII 

       190        200        210        220        230        240 
DEAYVDFGAR SSVPLIKEFE NLLVIQTLSK SRALAGLRVG FALGSEQLIE GLDRVKNSIN 

       250        260        270        280        290        300 
SYTLDRLALI GAEEAIKDHE YFCEIRDKII NTREWVSKKL SSMGFKVIES KANFIFISHP 

       310        320        330        340        350 
KINGRLLFEK YKENNILVRH FNSPRIDNFL RVSIGSDEEM NIFCEKTKEI IESLN

« Hide

References

[1]"Complete sequence of Clostridium thermocellum ATCC 27405."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D., Newcomb M., Richardson P.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27405 / DSM 1237.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000568 Genomic DNA. Translation: ABN51845.1.
RefSeqYP_001037038.1. NC_009012.1.

3D structure databases

ProteinModelPortalA3DD16.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3DD16.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4808212.
GenomeReviewsGene locus Cthe_0610 in contig CP000568_GR.
KEGGcth:Cthe_0610.
NMPDRfig|203119.1.peg.2450.
PATRIC19514887. VBICloThe47081_0635.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0079.
HOGENOMHBG646350.
OMAMKNSFNS.
ProtClustDBPRK05387.

Family and domain databases

HAMAPMF_01023. HisC_aminotrans_2.
[Tree]
InterProIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00817.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. HisC. 1 hit.
PROSITEPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3DD16_CLOTH
AccessionPrimary (citable) accession number: A3DD16
Entry history
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info