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Protein
Submitted name:

Sun protein

Gene

Cthe_0571

Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei291S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei318S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei336S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei389NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCTHE203119:G1G86-597-MONOMER

Names & Taxonomyi

Protein namesi
Submitted name:
Sun proteinImported
Gene namesi
Ordered Locus Names:Cthe_0571Imported
OrganismiClostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)Imported
Taxonomic identifieri203119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium
Proteomesi

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi203119.Cthe_0571

Structurei

3D structure databases

ProteinModelPortaliA3DCX8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini177 – 453SAM_MT_RSMB_NOPInterPro annotationAdd BLAST277

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni267 – 273S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ Bacteria
COG0144 LUCA
HOGENOMiHOG000037300
KOiK03500
OMAiLRVNRQH
OrthoDBiPOG091H02E2

Family and domain databases

Gene3Di1.10.940.10, 1 hit
InterProiView protein in InterPro
IPR031341 Methyltr_RsmF_N
IPR001678 MeTrfase_RsmB/NOP2
IPR011023 Nop2p
IPR035926 NusB-like_sf
IPR006027 NusB_RsmB_TIM44
IPR023267 RCMT
IPR004573 rRNA_ssu_MeTfrase_B
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF17125 Methyltr_RsmF_N, 1 hit
PF01029 NusB, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF48013 SSF48013, 1 hit
SSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00446 nop2p, 1 hit
TIGR00563 rsmB, 1 hit
PROSITEiView protein in PROSITE
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

A3DCX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMRTKVDKV RETALKILYD INEKGAYSNI SLNKYLNGQE FESIDRAFIT
60 70 80 90 100
DIVYGTLKWQ YTIDYLIEKF SSVKIKKISP WIFNILRMGI YQLIYTDKIP
110 120 130 140 150
FFAACNESVK LAAKYGHAAS SKYVNAVLRN IARNKENLPY PDRNNDTAHY
160 170 180 190 200
LSVKYSHPVW MVKDWLDCFG EEFTEGLLKA NNEVAPFTVR VNDLKISKKE
210 220 230 240 250
LVDILTKDGF EVENGKYLDE ALIIRNPSAV QKMDAFAKGY FQVQDESSML
260 270 280 290 300
VAKVLDPKPG ETILDVCSAP GGKSTHIAQI MKNRGTVISR DIHEHKIKLI
310 320 330 340 350
EQAKERLGLE IIKTEVFDAA VLDGKLIEKI DRVLVDAPCT GFGIIRRKPD
360 370 380 390 400
IKWSKNSEDK AEIVSLQHKI LSTASKYVKD GGVLVYSTCT LEPEENEKAV
410 420 430 440 450
ERFIEENKDF YLEDITEFLP DALRKESAGK GYIQLYPNID GIDGFFIARM

RKRSK
Length:455
Mass (Da):51,932
Last modified:March 20, 2007 - v1
Checksum:i9AB804C140B7A3F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA Translation: ABN51807.1
RefSeqiWP_003517649.1, NC_009012.1

Genome annotation databases

EnsemblBacteriaiABN51807; ABN51807; Cthe_0571
GeneIDi35805401
KEGGicth:Cthe_0571

Similar proteinsi

Entry informationi

Entry nameiA3DCX8_CLOTH
AccessioniPrimary (citable) accession number: A3DCX8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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