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A3DCR3

- A3DCR3_CLOTH

UniProt

A3DCR3 - A3DCR3_CLOTH

Protein
Submitted name:

Formate acetyltransferase

Gene

Cthe_0505

Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (20 Mar 2007)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei406 – 4061S-acetylcysteine intermediateUniRule annotation
    Active sitei407 – 4071Cysteine radical intermediateUniRule annotation

    GO - Molecular functioni

    1. formate C-acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseImported, Transferase

    Enzyme and pathway databases

    BioCyciCTHE203119:GIW8-520-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Formate acetyltransferaseImported (EC:2.3.1.54Imported)
    Gene namesi
    Ordered Locus Names:Cthe_0505Imported
    OrganismiClostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)Imported
    Taxonomic identifieri203119 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium
    ProteomesiUP000002145: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei717 – 7171Glycine radicalUniRule annotation

    Keywords - PTMi

    Organic radicalUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi203119.Cthe_0505.

    Structurei

    3D structure databases

    ProteinModelPortaliA3DCR3.
    SMRiA3DCR3. Positions 3-737.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains glycine radical domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG1882.
    HOGENOMiHOG000011346.
    KOiK00656.
    OMAiKMANNAL.
    OrthoDBiEOG6Q8J0J.

    Family and domain databases

    InterProiIPR005949. Form_AcTrfase.
    IPR019777. Form_AcTrfase_GR_CS.
    IPR001150. Gly_radical.
    IPR004184. PFL_dom.
    [Graphical view]
    PfamiPF01228. Gly_radical. 1 hit.
    PF02901. PFL. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000379. For_Ac_trans_1. 1 hit.
    TIGRFAMsiTIGR01255. pyr_form_ly_1. 1 hit.
    PROSITEiPS00850. GLY_RADICAL_1. 1 hit.
    PS51149. GLY_RADICAL_2. 1 hit.
    PS51554. PFL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A3DCR3-1 [UniParc]FASTAAdd to Basket

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    MDAWRGFNKG NWCQEIDVRD FIIRNYTPYE GDESFLVGPT DRTRKLWEKV    50
    SELLKKEREN GGVLDVDTHT ISTITSHKPG YIDKELEVIV GLQTDEPLKR 100
    AIMPFGGIRM VIKGAEAYGH SVDPQVVEIF TKYRKTHNQG VYDVYTPEMR 150
    KAKKAGIITG LPDAYGRGRI IGDYRRVALY GVDRLIAEKE KEMASLERDY 200
    IDYETVRDRE EISEQIKSLK QLKEMALSYG FDISCPAKDA REAFQWLYFA 250
    YLAAVKEQNG AAMSIGRIST FLDIYIERDL KEGKLTEELA QELVDQLVIK 300
    LRIVRFLRTP EYEKLFSGDP TWVTESIGGM ALDGRTLVTK SSFRFLHTLF 350
    NLGHAPEPNL TVLWSVNLPE GFKKYCAKVS IHSSSIQYES DDIMRKHWGD 400
    DYGIACCVSA MRIGKQMQFF GARCNLAKAL LYAINGGKDE MTGEQIAPMF 450
    APVETEYLDY EDVMKRFDMV LDWVARLYMN TLNIIHYMHD KYAYEALQMA 500
    LHDKDVFRTM ACGIAGLSVV ADSLSAIKYA KVKPIRNENN LVVDYEVEGD 550
    YPKFGNNDER VDEIAVQVVK MFMNKLRKQR AYRSATPTLS ILTITSNVVY 600
    GKKTGNTPDG RKAGEPLAPG ANPMHGRDIN GALAVLNSIA KLPYEYAQDG 650
    ISYTFSIIPK ALGRDEETRI NNLKSMLDGY FKQGGHHINV NVFEKETLLD 700
    AMEHPEKYPQ LTIRVSGYAV NFIKLTREQQ LDVINRTIHG KI 742
    Length:742
    Mass (Da):84,405
    Last modified:March 20, 2007 - v1
    Checksum:i3187CBCB67352E4A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000568 Genomic DNA. Translation: ABN51742.1.
    RefSeqiYP_001036935.1. NC_009012.1.

    Genome annotation databases

    EnsemblBacteriaiABN51742; ABN51742; Cthe_0505.
    GeneIDi4808305.
    KEGGicth:Cthe_0505.
    PATRICi19514673. VBICloThe47081_0531.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000568 Genomic DNA. Translation: ABN51742.1 .
    RefSeqi YP_001036935.1. NC_009012.1.

    3D structure databases

    ProteinModelPortali A3DCR3.
    SMRi A3DCR3. Positions 3-737.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 203119.Cthe_0505.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABN51742 ; ABN51742 ; Cthe_0505 .
    GeneIDi 4808305.
    KEGGi cth:Cthe_0505.
    PATRICi 19514673. VBICloThe47081_0531.

    Phylogenomic databases

    eggNOGi COG1882.
    HOGENOMi HOG000011346.
    KOi K00656.
    OMAi KMANNAL.
    OrthoDBi EOG6Q8J0J.

    Enzyme and pathway databases

    BioCyci CTHE203119:GIW8-520-MONOMER.

    Family and domain databases

    InterProi IPR005949. Form_AcTrfase.
    IPR019777. Form_AcTrfase_GR_CS.
    IPR001150. Gly_radical.
    IPR004184. PFL_dom.
    [Graphical view ]
    Pfami PF01228. Gly_radical. 1 hit.
    PF02901. PFL. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000379. For_Ac_trans_1. 1 hit.
    TIGRFAMsi TIGR01255. pyr_form_ly_1. 1 hit.
    PROSITEi PS00850. GLY_RADICAL_1. 1 hit.
    PS51149. GLY_RADICAL_2. 1 hit.
    PS51554. PFL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372Imported.

    Entry informationi

    Entry nameiA3DCR3_CLOTH
    AccessioniPrimary (citable) accession number: A3DCR3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 20, 2007
    Last sequence update: March 20, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3