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Protein
Submitted name:

Formate acetyltransferase

Gene

Cthe_0505

Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei406 – 4061S-acetylcysteine intermediateUniRule annotation
Active sitei407 – 4071Cysteine radical intermediateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseImported, Transferase

Enzyme and pathway databases

BioCyciCTHE203119:GIW8-520-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Formate acetyltransferaseImported (EC:2.3.1.54Imported)
Gene namesi
Ordered Locus Names:Cthe_0505Imported
OrganismiClostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)Imported
Taxonomic identifieri203119 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium
ProteomesiUP000002145 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei717 – 7171Glycine radicalUniRule annotation

Keywords - PTMi

Organic radicalUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi203119.Cthe_0505.

Structurei

3D structure databases

ProteinModelPortaliA3DCR3.
SMRiA3DCR3. Positions 3-737.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains glycine radical domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG1882.
HOGENOMiHOG000011346.
KOiK00656.
OMAiWEGFKNG.
OrthoDBiEOG6Q8J0J.

Family and domain databases

InterProiIPR005949. Form_AcTrfase.
IPR019777. Form_AcTrfase_GR_CS.
IPR001150. Gly_radical.
IPR004184. PFL_dom.
[Graphical view]
PfamiPF01228. Gly_radical. 1 hit.
PF02901. PFL. 1 hit.
[Graphical view]
PIRSFiPIRSF000379. For_Ac_trans_1. 1 hit.
TIGRFAMsiTIGR01255. pyr_form_ly_1. 1 hit.
PROSITEiPS00850. GLY_RADICAL_1. 1 hit.
PS51149. GLY_RADICAL_2. 1 hit.
PS51554. PFL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3DCR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAWRGFNKG NWCQEIDVRD FIIRNYTPYE GDESFLVGPT DRTRKLWEKV
60 70 80 90 100
SELLKKEREN GGVLDVDTHT ISTITSHKPG YIDKELEVIV GLQTDEPLKR
110 120 130 140 150
AIMPFGGIRM VIKGAEAYGH SVDPQVVEIF TKYRKTHNQG VYDVYTPEMR
160 170 180 190 200
KAKKAGIITG LPDAYGRGRI IGDYRRVALY GVDRLIAEKE KEMASLERDY
210 220 230 240 250
IDYETVRDRE EISEQIKSLK QLKEMALSYG FDISCPAKDA REAFQWLYFA
260 270 280 290 300
YLAAVKEQNG AAMSIGRIST FLDIYIERDL KEGKLTEELA QELVDQLVIK
310 320 330 340 350
LRIVRFLRTP EYEKLFSGDP TWVTESIGGM ALDGRTLVTK SSFRFLHTLF
360 370 380 390 400
NLGHAPEPNL TVLWSVNLPE GFKKYCAKVS IHSSSIQYES DDIMRKHWGD
410 420 430 440 450
DYGIACCVSA MRIGKQMQFF GARCNLAKAL LYAINGGKDE MTGEQIAPMF
460 470 480 490 500
APVETEYLDY EDVMKRFDMV LDWVARLYMN TLNIIHYMHD KYAYEALQMA
510 520 530 540 550
LHDKDVFRTM ACGIAGLSVV ADSLSAIKYA KVKPIRNENN LVVDYEVEGD
560 570 580 590 600
YPKFGNNDER VDEIAVQVVK MFMNKLRKQR AYRSATPTLS ILTITSNVVY
610 620 630 640 650
GKKTGNTPDG RKAGEPLAPG ANPMHGRDIN GALAVLNSIA KLPYEYAQDG
660 670 680 690 700
ISYTFSIIPK ALGRDEETRI NNLKSMLDGY FKQGGHHINV NVFEKETLLD
710 720 730 740
AMEHPEKYPQ LTIRVSGYAV NFIKLTREQQ LDVINRTIHG KI
Length:742
Mass (Da):84,405
Last modified:March 20, 2007 - v1
Checksum:i3187CBCB67352E4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN51742.1.
RefSeqiWP_003518002.1. NC_009012.1.

Genome annotation databases

EnsemblBacteriaiABN51742; ABN51742; Cthe_0505.
KEGGicth:Cthe_0505.
PATRICi19514673. VBICloThe47081_0531.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA. Translation: ABN51742.1.
RefSeqiWP_003518002.1. NC_009012.1.

3D structure databases

ProteinModelPortaliA3DCR3.
SMRiA3DCR3. Positions 3-737.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203119.Cthe_0505.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN51742; ABN51742; Cthe_0505.
KEGGicth:Cthe_0505.
PATRICi19514673. VBICloThe47081_0531.

Phylogenomic databases

eggNOGiCOG1882.
HOGENOMiHOG000011346.
KOiK00656.
OMAiWEGFKNG.
OrthoDBiEOG6Q8J0J.

Enzyme and pathway databases

BioCyciCTHE203119:GIW8-520-MONOMER.

Family and domain databases

InterProiIPR005949. Form_AcTrfase.
IPR019777. Form_AcTrfase_GR_CS.
IPR001150. Gly_radical.
IPR004184. PFL_dom.
[Graphical view]
PfamiPF01228. Gly_radical. 1 hit.
PF02901. PFL. 1 hit.
[Graphical view]
PIRSFiPIRSF000379. For_Ac_trans_1. 1 hit.
TIGRFAMsiTIGR01255. pyr_form_ly_1. 1 hit.
PROSITEiPS00850. GLY_RADICAL_1. 1 hit.
PS51149. GLY_RADICAL_2. 1 hit.
PS51554. PFL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372Imported.

Entry informationi

Entry nameiA3DCR3_CLOTH
AccessioniPrimary (citable) accession number: A3DCR3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: July 22, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.