A3DAT0 (RNPA_SHEB5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component
Short name=RNase P protein
Short name=RNaseP protein
EC=3.1.26.5

Alternative name(s):
Protein C5

Gene names

Name:	rnpA
Ordered Locus Names:	Sbal_4382

Organism

Shewanella baltica (strain OS155 / ATCC BAA-1091) [Complete proteome] [HAMAP]

Taxonomic identifier

325240 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella › Shewanella baltica

Protein attributes

Sequence length	118 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme By similarity. HAMAP-Rule MF_00227
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00227
Subunit structure	Consists of a catalytic RNA component (M1 or RnpB) and a protein subunit By similarity.
Sequence similarities	Belongs to the RnpA family.

Ontologies

Keywords
Biological process	tRNA processing
Ligand	RNA-binding
Molecular function	Endonuclease Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: EC tRNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 118	118	Ribonuclease P protein component HAMAP-Rule MF_00227		PRO_1000021456

Sequences

	Sequence		Length	Mass (Da)
	A3DAT0 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 89D880792113E919	FASTA	118	13,830
	10 20 30 40 50 60 MTSYTFSREL RLLTPAQFKS VFSNPIKASS AEITLLAIPN TEQHPRMGLT VAKRFVKRAN 70 80 90 100 110 QRNRIKRVIR DSFRLNQHDI PHLDIVVLVR NGVMEMENAE INKLIEKLWR KLSRRYNG

References

[1]

"Complete sequence of chromosome of Shewanella baltica OS155." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Brettar I., Klappenbach J., Konstantinidis K., Rodrigues J., Tiedje J., Richardson P. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OS155 / ATCC BAA-1091.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000563 Genomic DNA. Translation: ABN63843.1.
RefSeq	YP_001052712.1. NC_009052.1.
3D structure databases
ProteinModelPortal	A3DAT0.
ModBase	Search...
Protein-protein interaction databases
STRING	325240.Sbal_4382.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABN63843; ABN63843; Sbal_4382.
GeneID	4842346.
KEGG	sbl:Sbal_4382.
PATRIC	37188158. VBISheBal55297_4817.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0594.
HOGENOM	HOG000266301.
KO	K03536.
OMA	HFKAVFD.
ProtClustDB	PRK01732.
Enzyme and pathway databases
BioCyc	SBAL325240:GCTA-4517-MONOMER.
Family and domain databases
Gene3D	3.30.230.10. 1 hit.
HAMAP	MF_00227. RNase_P.
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR000100. RNase_P. IPR020539. RNase_P_CS. [Graphical view]
Pfam	PF00825. Ribonuclease_P. 1 hit. [Graphical view]
ProDom	PD003629. Ribonuclease_P. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR00188. rnpA. 1 hit.
PROSITE	PS00648. RIBONUCLEASE_P. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNPA_SHEB5

Accession

Primary (citable) accession number: A3DAT0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	March 20, 2007
Last modified:	May 29, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program