A3D130 (RLMG_SHEB5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase G
EC=2.1.1.174

Alternative name(s):
23S rRNA m2G1835 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RlmG

Gene names

Name:	rlmG
Ordered Locus Names:	Sbal_0918

Organism

Shewanella baltica (strain OS155 / ATCC BAA-1091) [Complete proteome] [HAMAP]

Taxonomic identifier

325240 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	378 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859
Catalytic activity	S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859
Subcellular location	Cytoplasm Potential HAMAP MF_01859.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 378	378	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366505

Sequences

	Sequence		Length	Mass (Da)
	A3D130 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 405FBD657697F6E3	FASTA	378	41,863
	10 20 30 40 50 60 MTTQFSVAGV ELELLRYPAQ QESNLQAWDA ADEHLLKSLI ESEQAAVPTA IINDSFGALS 70 80 90 100 110 120 CSVSKLNPSW PLCVETDART SFLGTEQNHG RNQLPLDNLQ WFTSRDTLPE NLALVLMKLP 130 140 150 160 170 180 KNLSYFAHQL TRLSQVLPAG TRILVAAKAK SINGALLDVF AKHLGPASAS LAWKNTRVIT 190 200 210 220 230 240 CISDGKPRPL AKEVTWAVPE YQLEISNLSN VFAANKLDIG ARIMLENLPK GDFKSIVDLG 250 260 270 280 290 300 CGNGVLGLRT AQLFPEADIH FIDDSEMAVA SAKANWARNQ LPADKGHFYW DDCMTHLPEE 310 320 330 340 350 360 VQPDLVLCNP PFHQGEAITD HIAWQMFLDA RRRLKDGGIL HIVGNRHLAY HVKLQRLFKN 370 CTTVASNGKF VILQAQKK

References

[1]

"Complete sequence of chromosome of Shewanella baltica OS155." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Brettar I., Klappenbach J., Konstantinidis K., Rodrigues J., Tiedje J., Richardson P. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OS155 / ATCC BAA-1091.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000563 Genomic DNA. Translation: ABN60443.1.
RefSeq	YP_001049312.1. NC_009052.1.
3D structure databases
ProteinModelPortal	A3D130.
ModBase	Search...
Protein-protein interaction databases
STRING	A3D130.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4845044.
GenomeReviews	Gene locus Sbal_0918 in contig CP000563_GR.
KEGG	sbl:Sbal_0918.
NMPDR	fig|325240.3.peg.1084.
PATRIC	37180599. VBISheBal55297_1158.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2813.
HOGENOM	HBG321931.
OMA	NRHLGYH.
PhylomeDB	A3D130.
ProtClustDB	CLSK906089.
Family and domain databases
HAMAP	MF_01859. 23SrRNA_methyltr_G. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_SHEB5

Accession

Primary (citable) accession number: A3D130

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	March 20, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program