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A3CZN8 (A3CZN8_SHEB5) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylamine--glycine ligase HAMAP-Rule MF_00138
EC=6.3.4.13 HAMAP-Rule MF_00138
Alternative name(s):
GARS HAMAP-Rule MF_00138
Glycinamide ribonucleotide synthetase HAMAP-Rule MF_00138
Phosphoribosylglycinamide synthetase HAMAP-Rule MF_00138
Gene names
Name:purD HAMAP-Rule MF_00138
Ordered Locus Names:Sbal_0419 EMBL ABN59951.1
OrganismShewanella baltica (strain OS155 / ATCC BAA-1091) [Complete proteome] [HAMAP] EMBL ABN59951.1
Taxonomic identifier325240 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella ›

Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide. HAMAP-Rule MF_00138

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. HAMAP-Rule MF_00138

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. HAMAP-Rule MF_00138

Sequence similarities

Belongs to the GARS family. HAMAP-Rule MF_00138

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00138

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain109 – 320212ATP-grasp By similarity HAMAP-Rule MF_00138
Nucleotide binding139 – 20062ATP By similarity HAMAP-Rule MF_00138

Sites

Metal binding2901Magnesium or manganese By similarity HAMAP-Rule MF_00138
Metal binding2921Magnesium or manganese By similarity HAMAP-Rule MF_00138

Sequences

Sequence LengthMass (Da)Tools
A3CZN8 [UniParc].

Last modified March 20, 2007. Version 1.
Checksum: 81A119D617EF06CE

FASTA43245,690
        10         20         30         40         50         60 
MKVLVIGGGG REHALAWKAA QSAQVETVYV APGNAGTALE PNVENLAISA TDIPALLDFA 

        70         80         90        100        110        120 
KTNKIELTIV GPEAPLVMGV VDAFNAAGLP IFGPTKAAAQ LEGSKAFTKD FLARHNIPTA 

       130        140        150        160        170        180 
GYKNCTEISD AKAFVRELTA TTGYPVVIKA DGLAAGKGVI IAQDQAEADA AIDDMLAGNK 

       190        200        210        220        230        240 
FGDAGSHVVI EEFLKGEEAS FIVMVDGKNI LPMATSQDHK ARDNGDYGPN TGGMGAYSPA 

       250        260        270        280        290        300 
PVVTQAVHDW TVANVIRPTV DGMAAEGNVY TGFLYAGLMI SPDGSAKVLE YNCRFGDPET 

       310        320        330        340        350        360 
QPIMMRLKSD LVELCLAATR GELDKVTAEY DERAAVGVVL AAGGYPDEYR KFDVIDGLSL 

       370        380        390        400        410        420 
GDNDGKVFHA GTEMKDGHVV TNGGRVLCAT ALGNTVTEAQ KAAYKLVDEI HWDDVYFRTD 

       430 
IGYRAIAREQ QD

« Hide

References

[1]"Complete sequence of chromosome of Shewanella baltica OS155."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Brettar I., Klappenbach J., Konstantinidis K., Rodrigues J., Tiedje J., Richardson P.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OS155 / ATCC BAA-1091.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000563 Genomic DNA. Translation: ABN59951.1.
RefSeqYP_001048820.1. NC_009052.1.

3D structure databases

ProteinModelPortalA3CZN8.
SMRA3CZN8. Positions 1-428.
ModBaseSearch...

Protein-protein interaction databases

STRING325240.Sbal_0419.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABN59951; ABN59951; Sbal_0419.
GeneID4841375.
KEGGsbl:Sbal_0419.
PATRIC37179541. VBISheBal55297_0633.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0151.
HOGENOMHOG000033463.
KOK01945.
OMAMGAYTPL.
ProtClustDBPRK00885.

Enzyme and pathway databases

BioCycSBAL325240:GCTA-433-MONOMER.
UniPathwayUPA00074; UER00125.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.600.10. 1 hit.
HAMAPMF_00138. GARS.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR020561. PRibGlycinamid_synth_ATP-grasp.
IPR000115. PRibGlycinamide_synth.
IPR020560. PRibGlycinamide_synth_C-dom.
IPR020559. PRibGlycinamide_synth_CS.
IPR020562. PRibGlycinamide_synth_N.
IPR011054. Rudment_hybrid_motif.
[Graphical view]
PfamPF01071. GARS_A. 1 hit.
PF02843. GARS_C. 1 hit.
PF02844. GARS_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMsTIGR00877. purD. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00184. GARS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3CZN8_SHEB5
AccessionPrimary (citable) accession number: A3CZN8
Entry history
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: May 29, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info