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Protein
Submitted name:

D-3-phosphoglycerate dehydrogenase

Gene

Memar_1850

Organism
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. amino acid binding Source: InterPro
  2. NAD binding Source: InterPro
  3. phosphoglycerate dehydrogenase activity Source: UniProtKB-EC

GO - Biological processi

  1. L-serine biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciMMAR368407:GH7L-1894-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
D-3-phosphoglycerate dehydrogenaseImported (EC:1.1.1.95Imported)
Gene namesi
Ordered Locus Names:Memar_1850Imported
OrganismiMethanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)Imported
Taxonomic identifieri368407 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanomicrobiaceaeMethanoculleus
ProteomesiUP000002146: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi368407.Memar_1850.

Structurei

3D structure databases

ProteinModelPortaliA3CWM6.
SMRiA3CWM6. Positions 1-302.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0111.
HOGENOMiHOG000136693.
KOiK00058.
OMAiITLHVPM.

Family and domain databases

Gene3Di3.30.1330.90. 1 hit.
3.40.50.720. 2 hits.
InterProiIPR002912. ACT_dom.
IPR029009. ASB_dom.
IPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
IPR006236. PGDH.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
PF01842. ACT. 1 hit.
[Graphical view]
SUPFAMiSSF143548. SSF143548. 1 hit.
TIGRFAMsiTIGR01327. PGDH. 1 hit.
PROSITEiPS51671. ACT. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3CWM6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKYRVLVSDP LAEEGIDILR EFCDVDVNTG LTEDQLVAII GDYDGLLVRS
60 70 80 90 100
GTEVTAQVID AGAKLKFIGR AGAGVDNIDT DAATRRGIIV ANAPEGNTLA
110 120 130 140 150
ATEHTMAMML SLARNIPQAT ASLKKGEWKR SKFMGVELND KILGIMGFGR
160 170 180 190 200
IGREVAKRAQ AMQMKCIAYD PFITQERAAS LGVEMVPLDE LFRRADVITV
210 220 230 240 250
HTPLIKETRH VINAETIATM RDGVRLINCA RGGIIDEKAL ADAVASGKVA
260 270 280 290 300
GAALDVFENE PPTDSPLLGL DKVIVTPHLG ASTVEAQKNV AVSVANQCIS
310 320 330 340 350
VLSGGSAKYV VNAPMIPAEQ QALVEPYAML AQKMGSLLIQ LVEGRLESLE
360 370 380 390 400
ITYGGEAAGL PNTKFVTRVI LKGMLDPILQ VPANIVNAEF VAKERGIRMS
410 420 430 440 450
ETTTEEAQGF KNIITITAKT DRMTETVSGS VSGPNRARIV SIGGYMTDLT
460 470 480 490 500
PTGHVVISRH TDKPGVIGKA ATILGSVNVN IAGMQVGRNK PGEEALMVLT
510 520
VDSAVPADAM DEIKKIDGIH TAKHAEI
Length:527
Mass (Da):56,095
Last modified:March 20, 2007 - v1
Checksum:i899B545F242022C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000562 Genomic DNA. Translation: ABN57776.1.
RefSeqiYP_001047758.1. NC_009051.1.

Genome annotation databases

EnsemblBacteriaiABN57776; ABN57776; Memar_1850.
GeneIDi4848121.
KEGGimem:Memar_1850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000562 Genomic DNA. Translation: ABN57776.1.
RefSeqiYP_001047758.1. NC_009051.1.

3D structure databases

ProteinModelPortaliA3CWM6.
SMRiA3CWM6. Positions 1-302.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi368407.Memar_1850.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN57776; ABN57776; Memar_1850.
GeneIDi4848121.
KEGGimem:Memar_1850.

Phylogenomic databases

eggNOGiCOG0111.
HOGENOMiHOG000136693.
KOiK00058.
OMAiITLHVPM.

Enzyme and pathway databases

BioCyciMMAR368407:GH7L-1894-MONOMER.

Family and domain databases

Gene3Di3.30.1330.90. 1 hit.
3.40.50.720. 2 hits.
InterProiIPR002912. ACT_dom.
IPR029009. ASB_dom.
IPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
IPR006236. PGDH.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
PF01842. ACT. 1 hit.
[Graphical view]
SUPFAMiSSF143548. SSF143548. 1 hit.
TIGRFAMsiTIGR01327. PGDH. 1 hit.
PROSITEiPS51671. ACT. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35101 / DSM 1498 / JR1Imported.

Entry informationi

Entry nameiA3CWM6_METMJ
AccessioniPrimary (citable) accession number: A3CWM6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: February 4, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.