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Protein

DNA polymerase sliding clamp

Gene

pcn

Organism
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Enzyme and pathway databases

BioCyciMMAR368407:G1G85-1460-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clampUniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homologUniRule annotation
Short name:
PCNAUniRule annotation
Gene namesi
Name:pcnUniRule annotation
Ordered Locus Names:Memar_1463
OrganismiMethanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Taxonomic identifieri368407 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanomicrobiaceaeMethanoculleus
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001329701 – 247DNA polymerase sliding clampAdd BLAST247

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Protein-protein interaction databases

STRINGi368407.Memar_1463

Structurei

3D structure databases

ProteinModelPortaliA3CVJ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
HOGENOMiHOG000222371
KOiK04802
OMAiSDGFDKY
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN

Sequencei

Sequence statusi: Complete.

A3CVJ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKATIDAEI FRESIDAIAA LVTECRLHTA EDQIRTRSVD TANVAMVSLE
60 70 80 90 100
LQSTAFNSFS ATAGELGLDI AKMKNIIGMM GKGDALTLTL LDEERKLELS
110 120 130 140 150
FGGYRYSISL LDVNTIRKDP NPPGIDLPGK AVVPGDALNN AIKAAAVISD
160 170 180 190 200
KIALGIDPDA MTFYMEAEGD TDHIKLALGE DELVALSPVQ ARSLFSIDYL
210 220 230 240
KDMGRVMARA DKVEVYLGID HPVRFVFDIA DGNGRVEYLL APRIEAD
Length:247
Mass (Da):26,790
Last modified:March 20, 2007 - v1
Checksum:i1964B8428B6251E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000562 Genomic DNA Translation: ABN57392.1
RefSeqiWP_011844303.1, NC_009051.1

Genome annotation databases

EnsemblBacteriaiABN57392; ABN57392; Memar_1463
GeneIDi4848056
KEGGimem:Memar_1463

Similar proteinsi

Entry informationi

Entry nameiPCNA_METMJ
AccessioniPrimary (citable) accession number: A3CVJ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 20, 2007
Last modified: April 25, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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