A3CTK0 (DCD_METMJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Memar_0767

Organism

Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) [Complete proteome] [HAMAP]

Taxonomic identifier

368407 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanomicrobiaceae › Methanoculleus

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 187	187	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000117984

Sequences

	Sequence		Length	Mass (Da)
	A3CTK0 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 76DE6F478589AED2	FASTA	187	21,223
	10 20 30 40 50 60 MILVDWQIED RIRRGHIRVD PFEPGLIQPN SLDIRLGSHF VWYVPGETVI DPYDSETVCR 70 80 90 100 110 120 DTEEMVADSI VLAPGRFLLA ETLEAIELPD DIVASIEGKS SIARLGVELH QTGGWIDAGF 130 140 150 160 170 180 RGTITLEMCN VNSRPVKVYA GMPIGQLVFY RTDRAARPYN MKQDAKYMDQ QQATLSRYHE NARRAEE

References

[1]

"Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981 type strain JR1." Anderson I.J., Sieprawska-Lupa M., Lapidus A., Nolan M., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Barry K., Saunders E., Han C., Brettin T., Detter J.C., Bruce D., Mikhailova N., Pitluck S., Hauser L., Land M. , Lucas S., Richardson P., Whitman W.B., Kyrpides N.C. Stand. Genomic Sci. 1:189-196(2009) [PubMed: 21304656] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35101 / DSM 1498 / JR1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000562 Genomic DNA. Translation: ABN56700.1.
RefSeq	YP_001046682.1. NC_009051.1.
3D structure databases
ProteinModelPortal	A3CTK0.
ModBase	Search...
Protein-protein interaction databases
STRING	A3CTK0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4847904.
GenomeReviews	Gene locus Memar_0767 in contig CP000562_GR.
KEGG	mem:Memar_0767.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG05800.
HOGENOM	HBG553199.
OMA	HQTAGWI.
PhylomeDB	A3CTK0.
ProtClustDB	CLSK949569.
Enzyme and pathway databases
BioCyc	MMAR368407:MEMAR_0767-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_METMJ

Accession

Primary (citable) accession number: A3CTK0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 20, 2007
Last modified:	November 16, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program