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A3CSQ6 (TF2B_METMJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transcription initiation factor IIB

Short name=TFIIB
Gene names
Name:tfb
Ordered Locus Names:Memar_0473
OrganismMethanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) [Complete proteome] [HAMAP]
Taxonomic identifier368407 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanomicrobiaceaeMethanoculleus

Protein attributes

Sequence length337 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB) By similarity. HAMAP-Rule MF_00383

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00383

Sequence similarities

Belongs to the TFIIB family.

Contains 1 TFIIB-type zinc finger.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 337337Transcription initiation factor IIB HAMAP-Rule MF_00383
PRO_1000080110

Regions

Repeat154 – 237841 HAMAP-Rule MF_00383
Repeat248 – 329822 HAMAP-Rule MF_00383
Zinc finger36 – 6833TFIIB-type HAMAP-Rule MF_00383

Sites

Metal binding411Zinc By similarity
Metal binding441Zinc By similarity
Metal binding601Zinc By similarity
Metal binding631Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A3CSQ6 [UniParc].

Last modified March 20, 2007. Version 1.
Checksum: C4B988E6D9A85617

FASTA33738,278
        10         20         30         40         50         60 
MAEVEKLKQL QLQREALKKR GEQKVKETEK KRTEESVQSV CPECGSRQLV HDYERAELVC 

        70         80         90        100        110        120 
QNCGLVLDEE FIDRGPEWRA FDHDQRMKRS RVGAPMTFTI HDKGLSTMID WRNRDSYGRA 

       130        140        150        160        170        180 
ISSKNRAQLY RLRKWQRRIR VSNATERNLA FALSELDRMA SALGLPRNVR ETAAVVYRDA 

       190        200        210        220        230        240 
VDKNLIRGRS IEGVAAAALY AACRQCSVPR TLDEIAEVSR VSRKEIGRTY RFISRELGLK 

       250        260        270        280        290        300 
LLPTSPIDYV PRFCSGLNLK GEVQSRAVEI LRQAGERELT SGRGPTGVAA AAIYISSILG 

       310        320        330 
GERRTQREVA EVAGVTEVTI RNRYKELAEK LDIEIIL 

« Hide

References

[1]"Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981 type strain JR1."
Anderson I.J., Sieprawska-Lupa M., Lapidus A., Nolan M., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Barry K., Saunders E., Han C., Brettin T., Detter J.C., Bruce D., Mikhailova N., Pitluck S., Hauser L., Land M. expand/collapse author list , Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.
Stand. Genomic Sci. 1:189-196(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35101 / DSM 1498 / JR1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000562 Genomic DNA. Translation: ABN56406.1.
RefSeqYP_001046388.1. NC_009051.1.

3D structure databases

ProteinModelPortalA3CSQ6.
SMRA3CSQ6. Positions 38-82, 141-335.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING368407.Memar_0473.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABN56406; ABN56406; Memar_0473.
GeneID4847082.
KEGGmem:Memar_0473.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1405.
HOGENOMHOG000108633.
KOK03124.
OMAWRAFDHD.

Enzyme and pathway databases

BioCycMMAR368407:GH7L-482-MONOMER.

Family and domain databases

Gene3D1.10.472.10. 2 hits.
HAMAPMF_00383. TF2B_arch.
InterProIPR013763. Cyclin-like.
IPR000812. TFIIB.
IPR023484. TFIIB_arc.
IPR023486. TFIIB_CS.
IPR013150. TFIIB_cyclin.
IPR013137. Znf_TFIIB.
[Graphical view]
PANTHERPTHR11618. PTHR11618. 1 hit.
PfamPF08271. TF_Zn_Ribbon. 1 hit.
PF00382. TFIIB. 2 hits.
[Graphical view]
PRINTSPR00685. TIFACTORIIB.
SMARTSM00385. CYCLIN. 2 hits.
[Graphical view]
SUPFAMSSF47954. SSF47954. 2 hits.
PROSITEPS00782. TFIIB. 2 hits.
PS51134. ZF_TFIIB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTF2B_METMJ
AccessionPrimary (citable) accession number: A3CSQ6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 20, 2007
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families