Reviewed, UniProtKB/Swiss-Prot A3CSK8 (APGM_METMJ)

Names and origin

Protein names

Recommended name:
    2,3-bisphosphoglycerate-independent phosphoglycerate mutase
      Short name=Phosphoglyceromutase
      Short name=BPG-independent PGAM
      Short name=aPGAM
    EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Memar_0425

Organism

Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) [Complete proteome] [HAMAP]

Taxonomic identifier

368407 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanomicrobiaceae › Methanoculleus

Protein attributes

Sequence length	411 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 411	411	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402		PRO_1000068383

Sequences

	Sequence		Length	Mass (Da)
	A3CSK8-1 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 722732F4434AB887	FASTA	411	43,429
	10 20 30 40 50 60 MIAEKVLFLV LDGISDRPCE ALDGLTPLAA ARTPVLDRLA AEGVCGIMDS VAPGIRPGSD 70 80 90 100 110 120 TSHLALLGYP PQEFYTGRGP LEAEGTGIHM TAGMIGFRCN FATVDADGLV TDRRAGRISG 130 140 150 160 170 180 TEPLAEAIRE GVDLSGLGLE FRFEAGAGHR AALALIGEGL GDKVSSNDPK KEGVQPLTIR 190 200 210 220 230 240 PGSDDPADAK TARACNEFIR QSREILDGHP VNVRRMEEGL PPGNLLLIRG AGKMGALPQF 250 260 270 280 290 300 PERYGLSGSV ISAATLISGI GMVVGLEHIP VPGTTGSVDS DLDAKVRAAI GELGRKDFVL 310 320 330 340 350 360 MNIKGADEAG HDGKSIQKRD FIEVIDKALA PLLDLKNTLI LVCADHSTPC SVKDHSADPV 370 380 390 400 410 PVVIRGPGVR IDRTNRFDEV SCAEGGLHRI RGRDLMPIIL DLINKSHKYG A

References

[1]

"Complete sequence of Methanoculleus marisnigri JR1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Anderson I., Sieprawska-Lupa M., Whitman W., Woese C., Richardson P. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000562 Genomic DNA. Translation: ABN56358.1.
RefSeq	YP_001046340.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A3CSK8.
Genome annotation databases
GeneID	4847528.
GenomeReviews	Gene locus Memar_0425 in contig CP000562_GR.
KEGG	mem:Memar_0425.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ITGDHST.
Family and domain databases
HAMAP	MF_01402. [Tree]
InterPro	IPR004456. APGAM_arc. IPR019304. bisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
ProDom	PD004704. APGAM_DeoB. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00306. apgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_METMJ

Accession

Primary (citable) accession number: A3CSK8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	March 20, 2007
Last modified:	November 3, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)