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A3CRT9

- ARGB_METMJ

UniProt

A3CRT9 - ARGB_METMJ

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Protein

Acetylglutamate kinase

Gene

argB

Organism
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei25 – 251Transition state stabilizerUniRule annotation
Binding sitei82 – 821SubstrateUniRule annotation
Binding sitei186 – 1861SubstrateUniRule annotation
Sitei247 – 2471Transition state stabilizerUniRule annotation

GO - Molecular functioni

  1. acetylglutamate kinase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW
  3. glutamate 5-kinase activity Source: InterPro

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-UniPathway
  2. proline biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR368407:GH7L-154-MONOMER.
UniPathwayiUPA00068; UER00107.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylglutamate kinaseUniRule annotation (EC:2.7.2.8UniRule annotation)
Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferaseUniRule annotation
NAG kinaseUniRule annotation
Short name:
AGKUniRule annotation
Gene namesi
Name:argBUniRule annotation
Ordered Locus Names:Memar_0154
OrganismiMethanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Taxonomic identifieri368407 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanomicrobiaceaeMethanoculleus
ProteomesiUP000002146: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 289289Acetylglutamate kinasePRO_1000010509Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi368407.Memar_0154.

Structurei

3D structure databases

ProteinModelPortaliA3CRT9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni60 – 612Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the acetylglutamate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0548.
HOGENOMiHOG000233259.
KOiK00930.
OMAiFDVHTDL.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
HAMAPiMF_00082_A. ArgB_A.
MF_00082_B. ArgB_B.
InterProiIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000728. NAGK. 1 hit.
PRINTSiPR00474. GLU5KINASE.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00761. argB. 1 hit.

Sequencei

Sequence statusi: Complete.

A3CRT9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKREDVLMEA LPYIQKFYGK TIVIKLGGHA MVDQSILETV IRDAVLLRYV
60 70 80 90 100
GMKVVLVHGG GPEITAKMQA MGKEPKFVGG LRITDPETLE IAQMVLVGKI
110 120 130 140 150
NDGIVSLIAN CGTRAVGISG NDGNLLIARK MDPQRVQVGE VMQEVDLGQV
160 170 180 190 200
GEIEEVDPEV LHCLLAQNYI PVVAPIAIDR QGMSLNINAD TAAAEIAIAL
210 220 230 240 250
SAFKLVNLTD VDGVMDADRT MVYHRLALTE AEAMIGAGVI AGGMIPKLEG
260 270 280
CMKAVRNGVA SAHVVNGNRE HNLLLELFTD QGVGTMLTL
Length:289
Mass (Da):30,949
Last modified:March 20, 2007 - v1
Checksum:i0623127845D9795F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000562 Genomic DNA. Translation: ABN56089.1.
RefSeqiYP_001046071.1. NC_009051.1.

Genome annotation databases

EnsemblBacteriaiABN56089; ABN56089; Memar_0154.
GeneIDi4848336.
KEGGimem:Memar_0154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000562 Genomic DNA. Translation: ABN56089.1 .
RefSeqi YP_001046071.1. NC_009051.1.

3D structure databases

ProteinModelPortali A3CRT9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 368407.Memar_0154.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABN56089 ; ABN56089 ; Memar_0154 .
GeneIDi 4848336.
KEGGi mem:Memar_0154.

Phylogenomic databases

eggNOGi COG0548.
HOGENOMi HOG000233259.
KOi K00930.
OMAi FDVHTDL.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00107 .
BioCyci MMAR368407:GH7L-154-MONOMER.

Family and domain databases

Gene3Di 3.40.1160.10. 1 hit.
HAMAPi MF_00082_A. ArgB_A.
MF_00082_B. ArgB_B.
InterProi IPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
[Graphical view ]
Pfami PF00696. AA_kinase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000728. NAGK. 1 hit.
PRINTSi PR00474. GLU5KINASE.
SUPFAMi SSF53633. SSF53633. 1 hit.
TIGRFAMsi TIGR00761. argB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35101 / DSM 1498 / JR1.

Entry informationi

Entry nameiARGB_METMJ
AccessioniPrimary (citable) accession number: A3CRT9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 20, 2007
Last modified: November 26, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3