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A3CPH0

- LACG_STRSV

UniProt

A3CPH0 - LACG_STRSV

Protein

6-phospho-beta-galactosidase

Gene

lacG

Organism
Streptococcus sanguinis (strain SK36)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (20 Mar 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei160 – 1601Proton donorUniRule annotation
    Active sitei375 – 3751NucleophileUniRule annotation

    GO - Molecular functioni

    1. 6-phospho-beta-galactosidase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. lactose catabolic process via tagatose-6-phosphate Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Enzyme and pathway databases

    BioCyciSSAN388919:GHEN-1654-MONOMER.
    UniPathwayiUPA00542; UER00605.

    Protein family/group databases

    CAZyiGH1. Glycoside Hydrolase Family 1.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phospho-beta-galactosidaseUniRule annotation (EC:3.2.1.85UniRule annotation)
    Alternative name(s):
    Beta-D-phosphogalactoside galactohydrolaseUniRule annotation
    Short name:
    PGALaseUniRule annotation
    P-beta-GalUniRule annotation
    Short name:
    PBGUniRule annotation
    Gene namesi
    Name:lacGUniRule annotation
    Ordered Locus Names:SSA_1692
    OrganismiStreptococcus sanguinis (strain SK36)
    Taxonomic identifieri388919 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000002148: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 4684686-phospho-beta-galactosidasePRO_1000069209Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi388919.SSA_1692.

    Structurei

    3D structure databases

    ProteinModelPortaliA3CPH0.
    SMRiA3CPH0. Positions 1-468.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2723.
    HOGENOMiHOG000088632.
    KOiK01220.
    OMAiIGRREAP.
    OrthoDBiEOG60658J.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    HAMAPiMF_01574. LacG.
    InterProiIPR005928. 6P-beta-galactosidase.
    IPR001360. Glyco_hydro_1.
    IPR018120. Glyco_hydro_1_AS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR10353. PTHR10353. 1 hit.
    PfamiPF00232. Glyco_hydro_1. 1 hit.
    [Graphical view]
    PRINTSiPR00131. GLHYDRLASE1.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    TIGRFAMsiTIGR01233. lacG. 1 hit.
    PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
    PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A3CPH0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKSLPKDFI FGGATAAYQA EGATHTDGKG PVAWDKYLED NYWYTAEPAS    50
    DFYHKYPVDL KLAEEYGVNG IRISIAWSRI FPTGYGEVNP KGVEFYHNLF 100
    AECHKRHVEP FVTLHHFDTP EALHSNGDFL NRENIEHFVN YAAFCFEEFP 150
    EVRYWTTFNE IGPIGDGQYL VGKFPPGIQY DLAKVFQSHH NMMVSHARAV 200
    KLYKDKGYKG EIGVVHALPT KYPYDPENPA DVRAAELEDI IHNKFILDAT 250
    YLGHYSDVTL AGVNHILKVN GGQLDLRDED FAALEAAKDL NDFLGINYYM 300
    SDWMRDFDGE TEIIHNGKGE KGSSKYQIKG VGRRESPTHI PKTDWDWIIY 350
    PQGLYDQIMR IKKDYPNYKK IYITENGLGY KDEFVDNTVY DDARIDYVKQ 400
    HLEVLSDAIV DGANVKGYFI WSLMDVFSWS NGYEKRYGLF YVDFETQERY 450
    PKKSAHWYKK LAETQMIE 468
    Length:468
    Mass (Da):54,096
    Last modified:March 20, 2007 - v1
    Checksum:iB120824FC2874490
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000387 Genomic DNA. Translation: ABN45075.1.
    RefSeqiYP_001035625.1. NC_009009.1.

    Genome annotation databases

    EnsemblBacteriaiABN45075; ABN45075; SSA_1692.
    GeneIDi4807102.
    KEGGissa:SSA_1692.
    PATRICi19770297. VBIStrSan33173_1604.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000387 Genomic DNA. Translation: ABN45075.1 .
    RefSeqi YP_001035625.1. NC_009009.1.

    3D structure databases

    ProteinModelPortali A3CPH0.
    SMRi A3CPH0. Positions 1-468.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 388919.SSA_1692.

    Protein family/group databases

    CAZyi GH1. Glycoside Hydrolase Family 1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABN45075 ; ABN45075 ; SSA_1692 .
    GeneIDi 4807102.
    KEGGi ssa:SSA_1692.
    PATRICi 19770297. VBIStrSan33173_1604.

    Phylogenomic databases

    eggNOGi COG2723.
    HOGENOMi HOG000088632.
    KOi K01220.
    OMAi IGRREAP.
    OrthoDBi EOG60658J.

    Enzyme and pathway databases

    UniPathwayi UPA00542 ; UER00605 .
    BioCyci SSAN388919:GHEN-1654-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    HAMAPi MF_01574. LacG.
    InterProi IPR005928. 6P-beta-galactosidase.
    IPR001360. Glyco_hydro_1.
    IPR018120. Glyco_hydro_1_AS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR10353. PTHR10353. 1 hit.
    Pfami PF00232. Glyco_hydro_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00131. GLHYDRLASE1.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    TIGRFAMsi TIGR01233. lacG. 1 hit.
    PROSITEi PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
    PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SK36.

    Entry informationi

    Entry nameiLACG_STRSV
    AccessioniPrimary (citable) accession number: A3CPH0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: March 20, 2007
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3