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Protein

Putative sporulation transcription regulator WhiA

Gene

whiA

Organism
Streptococcus sanguinis (strain SK36)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be required for sporulation.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi272 – 30332H-T-H motifUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. endonuclease activity Source: InterPro

GO - Biological processi

  1. regulation of sporulation Source: UniProtKB-HAMAP
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSSAN388919:GHEN-814-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sporulation transcription regulator WhiAUniRule annotation
Gene namesi
Name:whiAUniRule annotation
Ordered Locus Names:SSA_0812
OrganismiStreptococcus sanguinis (strain SK36)
Taxonomic identifieri388919 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002148: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Putative sporulation transcription regulator WhiAPRO_0000376593Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi388919.SSA_0812.

Family & Domainsi

Sequence similaritiesi

Belongs to the WhiA transcriptional regulatory family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1481.
HOGENOMiHOG000040187.
KOiK09762.
OMAiHKFMLDA.
OrthoDBiEOG68WR87.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.
TIGRFAMsiTIGR00647. MG103. 1 hit.

Sequencei

Sequence statusi: Complete.

A3CM38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFTVKVKEE LLSLASRDKN ELSAMIKMSG SLGLASSGLT LSVTTENAKI
60 70 80 90 100
ARHLYELLSD LYQVKSEIRH HQKTNLRKNR VYTVFLDQKV EEILSDLHLA
110 120 130 140 150
DSFFGIEAGI DQAILTDDEA SRAYLRGAFL SNGSMREPDS GKYQLEILSV
160 170 180 190 200
YLDHAEDLAA LMRRFLLDAK TIERKKGAVT YLQRAEDIMD FLIVIGAMEA
210 220 230 240 250
MAEFESLKLM REARNDLNRA NNAETANIAR TVTASMKTIN NIAKISDNIG
260 270 280 290 300
IESLPVDLQE VAQLRIQHPD YSIQQLADSL SRPLTKSGVN HRLRKINKIA

DEL
Length:303
Mass (Da):34,013
Last modified:March 20, 2007 - v1
Checksum:iA27D62BE0F06FCF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000387 Genomic DNA. Translation: ABN44243.1.
RefSeqiYP_001034793.1. NC_009009.1.

Genome annotation databases

EnsemblBacteriaiABN44243; ABN44243; SSA_0812.
GeneIDi4805794.
KEGGissa:SSA_0812.
PATRICi19768632. VBIStrSan33173_0778.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000387 Genomic DNA. Translation: ABN44243.1.
RefSeqiYP_001034793.1. NC_009009.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi388919.SSA_0812.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN44243; ABN44243; SSA_0812.
GeneIDi4805794.
KEGGissa:SSA_0812.
PATRICi19768632. VBIStrSan33173_0778.

Phylogenomic databases

eggNOGiCOG1481.
HOGENOMiHOG000040187.
KOiK09762.
OMAiHKFMLDA.
OrthoDBiEOG68WR87.

Enzyme and pathway databases

BioCyciSSAN388919:GHEN-814-MONOMER.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.
TIGRFAMsiTIGR00647. MG103. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK36.

Entry informationi

Entry nameiWHIA_STRSV
AccessioniPrimary (citable) accession number: A3CM38
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: March 20, 2007
Last modified: March 4, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.