A3CM04 (GLGA_STRSV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	SSA_0778

Organism

Streptococcus sanguinis (strain SK36) [Complete proteome] [HAMAP]

Taxonomic identifier

388919 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	476 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	starch synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 476	476	Glycogen synthase HAMAP MF_00484		PRO_1000014385
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	A3CM04 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 143EC5F314826406	FASTA	476	54,265
	10 20 30 40 50 60 MKILFAAAEG APFSKTGGLG DVIGALPKSL VKAGHEVGVI LPYYDMTHAK FGDQVEDLFY 70 80 90 100 110 120 FEVSVGWRRQ YVGVKRLVLN GVSFYFIDNQ HYFFRGHVYG DFDDGERFAY FQLAAVELME 130 140 150 160 170 180 RIDFIPDVLH VHDYHTAMIP FLVKEKYHWI QAYQNITTVL TIHNLEFQGQ FPDSMLWELF 190 200 210 220 230 240 GVGYERYADG TLRWNDCLNW MKAGILYADR VTTVSPSYAS EIRTPEFGCN LDQILRMESG 250 260 270 280 290 300 KLVGIVNGID TDIYNPETDP LLAHHFDKSD LSGKLENKRA LQERVGLPVR DDVPVVGIVS 310 320 330 340 350 360 RLTRQKGFDL VVEELHNLLQ EDVQIILLGT GDPAFEQAFA WFGHAYPDKL SANILFDVTL 370 380 390 400 410 420 AQEIYAASDI FLMPSRFEPC GLSQMMAMRY GTLPLVHEVG GLRDTVEPYN VYTGKGTGFS 430 440 450 460 470 FNNFSGYWLT WTFKEALKLY ADDKEAWKSL QEQAMERDFS WDTASKAYSD LYQSLL

References

[1]

"Genome of the opportunistic pathogen Streptococcus sanguinis." Xu P., Alves J.M., Kitten T., Brown A., Chen Z., Ozaki L.S., Manque P., Ge X., Serrano M.G., Puiu D., Hendricks S., Wang Y., Chaplin M.D., Akan D., Paik S., Peterson D.L., Macrina F.L., Buck G.A. J. Bacteriol. 189:3166-3175(2007) [PubMed: 17277061] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SK36.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000387 Genomic DNA. Translation: ABN44209.1.
RefSeq	YP_001034759.1. NC_009009.1.
3D structure databases
ProteinModelPortal	A3CM04.
ModBase	Search...
Protein-protein interaction databases
STRING	A3CM04.
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000052534; EBSTRP00000048798; EBSTRG00000052524.
GeneID	4806429.
GenomeReviews	Gene locus SSA_0778 in contig CP000387_GR.
KEGG	ssa:SSA_0778.
NMPDR	fig|388919.8.peg.697.
PATRIC	19768564. VBIStrSan33173_0744.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0297.
GeneTree	EBGT00050000027459.
HOGENOM	HBG596384.
OMA	PIVHEIG.
PhylomeDB	A3CM04.
ProtClustDB	PRK00654.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
KO	K00703.
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. GlgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_STRSV

Accession

Primary (citable) accession number: A3CM04

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	March 20, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program