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Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus sanguinis (strain SK36)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathway: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciSSAN388919:GHEN-780-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:SSA_0778
OrganismiStreptococcus sanguinis (strain SK36)
Taxonomic identifieri388919 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002148 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Glycogen synthasePRO_1000014385Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi388919.SSA_0778.

Structurei

3D structure databases

ProteinModelPortaliA3CM04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

A3CM04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILFAAAEG APFSKTGGLG DVIGALPKSL VKAGHEVGVI LPYYDMTHAK
60 70 80 90 100
FGDQVEDLFY FEVSVGWRRQ YVGVKRLVLN GVSFYFIDNQ HYFFRGHVYG
110 120 130 140 150
DFDDGERFAY FQLAAVELME RIDFIPDVLH VHDYHTAMIP FLVKEKYHWI
160 170 180 190 200
QAYQNITTVL TIHNLEFQGQ FPDSMLWELF GVGYERYADG TLRWNDCLNW
210 220 230 240 250
MKAGILYADR VTTVSPSYAS EIRTPEFGCN LDQILRMESG KLVGIVNGID
260 270 280 290 300
TDIYNPETDP LLAHHFDKSD LSGKLENKRA LQERVGLPVR DDVPVVGIVS
310 320 330 340 350
RLTRQKGFDL VVEELHNLLQ EDVQIILLGT GDPAFEQAFA WFGHAYPDKL
360 370 380 390 400
SANILFDVTL AQEIYAASDI FLMPSRFEPC GLSQMMAMRY GTLPLVHEVG
410 420 430 440 450
GLRDTVEPYN VYTGKGTGFS FNNFSGYWLT WTFKEALKLY ADDKEAWKSL
460 470
QEQAMERDFS WDTASKAYSD LYQSLL
Length:476
Mass (Da):54,265
Last modified:March 20, 2007 - v1
Checksum:i143EC5F314826406
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000387 Genomic DNA. Translation: ABN44209.1.
RefSeqiWP_011836716.1. NC_009009.1.
YP_001034759.1. NC_009009.1.

Genome annotation databases

EnsemblBacteriaiABN44209; ABN44209; SSA_0778.
GeneIDi4806429.
KEGGissa:SSA_0778.
PATRICi19768564. VBIStrSan33173_0744.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000387 Genomic DNA. Translation: ABN44209.1.
RefSeqiWP_011836716.1. NC_009009.1.
YP_001034759.1. NC_009009.1.

3D structure databases

ProteinModelPortaliA3CM04.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi388919.SSA_0778.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN44209; ABN44209; SSA_0778.
GeneIDi4806429.
KEGGissa:SSA_0778.
PATRICi19768564. VBIStrSan33173_0744.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciSSAN388919:GHEN-780-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK36.

Entry informationi

Entry nameiGLGA_STRSV
AccessioniPrimary (citable) accession number: A3CM04
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 20, 2007
Last modified: June 24, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.