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A3CM01

- GLGB_STRSV

UniProt

A3CM01 - GLGB_STRSV

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Protein
1,4-alpha-glucan branching enzyme GlgB
Gene
glgB, SSA_0775
Organism
Streptococcus sanguinis (strain SK36)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei304 – 3041Nucleophile By similarity
Active sitei355 – 3551Proton donor By similarity

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciSSAN388919:GHEN-777-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgB (EC:2.4.1.18)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name:
BE
Gene namesi
Name:glgB
Ordered Locus Names:SSA_0775
OrganismiStreptococcus sanguinis (strain SK36)
Taxonomic identifieri388919 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002148: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6366361,4-alpha-glucan branching enzyme GlgBUniRule annotation
PRO_1000045003Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi388919.SSA_0775.

Structurei

3D structure databases

ProteinModelPortaliA3CM01.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000283037.
KOiK00700.
OMAiAKLLFMG.
OrthoDBiEOG6JX7GT.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

A3CM01-1 [UniParc]FASTAAdd to Basket

« Hide

MDKNEALRTF TTGENFHLQH YLGAHQDEVD GKSGYSFRVW APNAQSVHLI    50
GDFTNWYEEQ IPMVRNEAGV WEVFTELPKE GDIYKYNIKR SSGQEILKID 100
PLAIYLEERP GTGAVIRTIS EKKWKDGLWL ARRKRWGFFS RPVNIYEVHA 150
GSWKRNEDGS PYSFAQLKED LIPYLVEMNY THVEFMPLMA HPLGLSWGYQ 200
LMGYFAFEHT YGTPEEFQDF VEECHLNNIG VIVDWVPGHF TINDDALAYY 250
DGTPTFEYQD HDRAHNYGWG ALNFDLGKNQ VQSFLISSIK FWIDFYHLDG 300
IRVDAVSNML YLDYDSGPWQ PNKDGGNRNY EGYYFLQRLN TVIKLAHPDV 350
MMIAEESSSE TKITGMRELG GLGFDYKWNM GWMNDILRFY EEDPIYRKYD 400
FNLVTFSFMY AFSENFLLPF SHDEVVHGKK SLMHKMWGDR YNQFAGLRNL 450
LTYQICHPGK KLLFMGSEFG QFLEWKSEEQ LEWSNLDDQM NKKMQGFTAA 500
LNAFYKDNRP LWEIDLSYDG IEIIDADNTD QSVLSFIRKT EKGDMLVCVF 550
NMAPVERKNF TIGVPVEAIY EEVWNTELEE WGGVWKEHNE TVQSQEGLWK 600
DYPQTLTFTL PALGASIWKI KRRIARKNVK KDSTKE 636
Length:636
Mass (Da):74,463
Last modified:March 20, 2007 - v1
Checksum:i56E282A239B23E56
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000387 Genomic DNA. Translation: ABN44206.1.
RefSeqiYP_001034756.1. NC_009009.1.

Genome annotation databases

EnsemblBacteriaiABN44206; ABN44206; SSA_0775.
GeneIDi4806640.
KEGGissa:SSA_0775.
PATRICi19768558. VBIStrSan33173_0741.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000387 Genomic DNA. Translation: ABN44206.1 .
RefSeqi YP_001034756.1. NC_009009.1.

3D structure databases

ProteinModelPortali A3CM01.
ModBasei Search...

Protein-protein interaction databases

STRINGi 388919.SSA_0775.

Protein family/group databases

CAZyi CBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABN44206 ; ABN44206 ; SSA_0775 .
GeneIDi 4806640.
KEGGi ssa:SSA_0775.
PATRICi 19768558. VBIStrSan33173_0741.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000283037.
KOi K00700.
OMAi AKLLFMG.
OrthoDBi EOG6JX7GT.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci SSAN388919:GHEN-777-MONOMER.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_00685. GlgB.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK36.

Entry informationi

Entry nameiGLGB_STRSV
AccessioniPrimary (citable) accession number: A3CM01
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 20, 2007
Last modified: June 11, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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