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A3CLF6 (A3CLF6_STRSV) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aspartate--tRNA ligase 1 HAMAP MF_00044
EC=6.1.1.12 HAMAP MF_00044
Alternative name(s):
Aspartyl-tRNA synthetase 1 HAMAP MF_00044
Gene names
Name:aspS1 HAMAP MF_00044
Ordered Locus Names:SSA_0568
OrganismStreptococcus sanguinis (strain SK36) [Complete proteome] [HAMAP] EMBL ABN44011.1
Taxonomic identifier388919 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length578 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). HAMAP MF_00044

Subunit structure

Homodimer By similarity. HAMAP MF_00044

Subcellular location

Cytoplasm By similarity HAMAP MF_00044.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP MF_00044

Sequences

Sequence LengthMass (Da)Tools
A3CLF6 [UniParc].

Last modified March 20, 2007. Version 1.
Checksum: 44A575554BB30FB0

FASTA57866,122
        10         20         30         40         50         60 
MKEIFIGNYG LEQVGQTMTA TGWVANIRNH GKLAFIELRD REGLLQVFVG GEIEDFAKLE 

        70         80         90        100        110        120 
DIGKEDVIAV TGQVVQREER FVNKAIKSGQ VELRAEKIEV IASSKALPFE LDQHAHTGED 

       130        140        150        160        170        180 
LRQKYRYLDL RREKMTHNLK LRHQVTSTIR EYLNDLDFLE VETPYLTKST PEGARDFLVP 

       190        200        210        220        230        240 
SRVFKNQFYA LPQSPQMLKQ LLMGAGLERY YQIVRCFRDE DLRGDRQPEF TQVDLELSFA 

       250        260        270        280        290        300 
SEEEIRALVE AMLKAVVKKT HSLELTEAFP TISYEEAMSR FGSDKPDTRF GLELKTLTDL 

       310        320        330        340        350        360 
CQSNDSLLIK KALDNQEKVM GICVPDAASA FSKKQLSHYY QEMKEFGCSR FANLKVENGQ 

       370        380        390        400        410        420 
LVGDLASTFE AESQDLLARF EAKDGDLILL VMAKKRRAQE ALGHLRIEVA KALDLIDPSL 

       430        440        450        460        470        480 
LHFLWVVDWP LLEWNEDQNR YQAMHHPFTQ GIFEDGQEPD QFRSHAYDIV LNGYEIGGGS 

       490        500        510        520        530        540 
LRIHDRKAQE AMFELLGMSR EDYERDFGFF LEALEYGFPP HGGLALGLDR LVMILAGEEN 

       550        560        570 
IRQVIAFPKN GTGFDPMLES PSLVDQRQLK ELHLELKN

« Hide

References

[1]"Genome of the opportunistic pathogen Streptococcus sanguinis."
Xu P., Alves J.M., Kitten T., Brown A., Chen Z., Ozaki L.S., Manque P., Ge X., Serrano M.G., Puiu D., Hendricks S., Wang Y., Chaplin M.D., Akan D., Paik S., Peterson D.L., Macrina F.L., Buck G.A.
J. Bacteriol. 189:3166-3175(2007) [PubMed: 17277061] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000387 Genomic DNA. Translation: ABN44011.1.
RefSeqYP_001034561.1. NC_009009.1.

3D structure databases

ProteinModelPortalA3CLF6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3CLF6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTRT00000052646; EBSTRP00000048910; EBSTRG00000052636.
GeneID4807668.
GenomeReviewsGene locus SSA_0568 in contig CP000387_GR.
KEGGssa:SSA_0568.
NMPDRfig|388919.8.peg.511.
PATRIC19768170. VBIStrSan33173_0547.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0173.
GeneTreeEBGT00050000027607.
HOGENOMHBG396032.
OMALHFLWVV.
PhylomeDBA3CLF6.
ProtClustDBPRK00476.

Family and domain databases

HAMAPMF_00044_B. Asp_tRNA_synth_B.
[Tree]
InterProIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004524. Asp-tRNA-synth_IIb_bac/mt.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR004115. GAD_dom.
IPR012340. NA-bd_OB-fold.
IPR016027. NA-bd_OB-fold-like.
IPR004365. NA-bd_OB_tRNA-helicase.
[Graphical view]
Gene3DG3DSA:3.30.1360.30. GAD_dom. 1 hit.
G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KOK01876.
PANTHERPTHR22594. aa-tRNA-synt_II. 1 hit.
PTHR22594:SF5. AspS_bac. 1 hit.
PfamPF02938. GAD. 1 hit.
PF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
PRINTSPR01042. TRNASYNTHASP.
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
SSF55261. SSF55261. 1 hit.
TIGRFAMsTIGR00459. AspS_bact. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3CLF6_STRSV
AccessionPrimary (citable) accession number: A3CLF6
Entry history
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info