UniProtKB - A3C4N5 (PP2A4_ORYSJ)
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Protein
Serine/threonine-protein phosphatase PP2A-4 catalytic subunit
Gene
PP2A4
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Catalytic activityi
[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.
Cofactori
Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 62 | Manganese 1By similarity | 1 | |
Metal bindingi | 64 | Manganese 1By similarity | 1 | |
Metal bindingi | 90 | Manganese 1By similarity | 1 | |
Metal bindingi | 90 | Manganese 2By similarity | 1 | |
Metal bindingi | 122 | Manganese 2By similarity | 1 | |
Active sitei | 123 | Proton donorBy similarity | 1 | |
Metal bindingi | 172 | Manganese 2By similarity | 1 | |
Metal bindingi | 246 | Manganese 2By similarity | 1 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- phosphoprotein phosphatase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Hydrolase, Protein phosphatase |
Ligand | Manganese, Metal-binding |
Enzyme and pathway databases
BRENDAi | 3.1.3.16. 4460. |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:PP2A4 Ordered Locus Names:Os10g0410600, LOC_Os10g27050 ORF Names:OsJ_030257, OsJ_31490Imported |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000058864 | 1 – 314 | Serine/threonine-protein phosphatase PP2A-4 catalytic subunitAdd BLAST | 314 |
Proteomic databases
PaxDbi | A3C4N5. |
PRIDEi | A3C4N5. |
Expressioni
Gene expression databases
ExpressionAtlasi | A3C4N5. baseline and differential. |
Genevisiblei | A3C4N5. OS. |
Structurei
3D structure databases
ProteinModelPortali | A3C4N5. |
SMRi | A3C4N5. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0371. Eukaryota. COG0639. LUCA. |
InParanoidi | A3C4N5. |
KOi | K04382. |
OMAi | REHITIL. |
OrthoDBi | EOG09360EXD. |
Family and domain databases
Gene3Di | 3.60.21.10. 1 hit. |
InterProi | View protein in InterPro IPR004843. Calcineurin-like_PHP_ApaH. IPR029052. Metallo-depent_PP-like. IPR006186. Ser/Thr-sp_prot-phosphatase. |
Pfami | View protein in Pfam PF00149. Metallophos. 1 hit. |
PRINTSi | PR00114. STPHPHTASE. |
SMARTi | View protein in SMART SM00156. PP2Ac. 1 hit. |
PROSITEi | View protein in PROSITE PS00125. SER_THR_PHOSPHATASE. 1 hit. |
i Sequence
Sequence statusi: Complete.
A3C4N5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEESVGSRGG GGGGLDAQIE QLMECRPLSE PEVKTLCEKA KEILMEESNV
60 70 80 90 100
QPVKSPVTIC GDIHGQFHDL VELFRIGGKC PDTNYLFMGD YVDRGYYSVE
110 120 130 140 150
TVTLLVALKV RYPQRITILR GNHESRQITQ VYGFYDECLR KYGSANVWKI
160 170 180 190 200
FTDLFDYFPL TALVESEIFC LHGGLSPSID NLDSVRSLDR VQEVPHEGPM
210 220 230 240 250
CDLLWSDPDD RCGWGISPRG AGYTFGQDIS EQFNHTNNLK LVARAHQLVM
260 270 280 290 300
EGYNWAHEQK VVTIFSAPNY CYRCGNMASI LEVDDCRNHT FIQFEPAPRR
310
GEPDVTRRTP DYFL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DP000086 Genomic DNA. Translation: ABB47590.1. AP008216 Genomic DNA. Translation: BAF26492.1. AP014966 Genomic DNA. Translation: BAT10803.1. CM000147 Genomic DNA. Translation: EEE50943.1. AK099604 mRNA. Translation: BAG94218.1. |
RefSeqi | XP_015615022.1. XM_015759536.1. |
UniGenei | Os.56095. |
Genome annotation databases
EnsemblPlantsi | Os10t0410600-02; Os10t0410600-02; Os10g0410600. |
GeneIDi | 4348601. |
Gramenei | Os10t0410600-02; Os10t0410600-02; Os10g0410600. |
KEGGi | osa:4348601. |
Similar proteinsi
Entry informationi
Entry namei | PP2A4_ORYSJ | |
Accessioni | A3C4N5Primary (citable) accession number: A3C4N5 Secondary accession number(s): B7EPC1 Q9SBW3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 11, 2007 |
Last sequence update: | September 11, 2007 | |
Last modified: | March 28, 2018 | |
This is version 72 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |