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A3AZ88

- MT2C_ORYSJ

UniProt

A3AZ88 - MT2C_ORYSJ

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Protein

Metallothionein-like protein 2C

Gene

MT2C

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Metallothioneins have a high content of cysteine residues that bind various heavy metals.1 Publication
Acts as reactive oxygen species (ROS) scavenger in the cytosol. Possesses superoxide- and hydroxyl radical-scavenging activities in vitro.1 Publication

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Metal-thiolate cluster

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein-like protein 2C
Alternative name(s):
Class I metallothionein-like protein 2C
OsMT-I-2c
OsMT2b
Gene namesi
Name:MT2C
Synonyms:MTE
Ordered Locus Names:Os05g0111300, LOC_Os05g02070
ORF Names:OsJ_016110, P0016H04.13
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 5

Organism-specific databases

GrameneiA3AZ88.

Subcellular locationi

Cytoplasmcytosol 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8484Metallothionein-like protein 2CPRO_0000197408Add
BLAST

Expressioni

Tissue specificityi

Highly expressed in inflorescences. Expressed in roots and leaves.2 Publications

Inductioni

Sinergically down-regulated by RAC1 and sphingolipid elicitor.1 Publication

Gene expression databases

ExpressionAtlasiA3AZ88. baseline.

Structurei

3D structure databases

ProteinModelPortaliA3AZ88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiA3AZ88.
OMAiTEWHSIT.

Family and domain databases

InterProiIPR000347. Metalthion_15p.
[Graphical view]
PfamiPF01439. Metallothio_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3AZ88-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSCCGGNCGC GSGCQCGGGC GGCKMFPDVE ATATTKTFVL AAPSNKASSG
60 70 80
GMEMAVESGE NGGCGCNTCK CGTSCSGCSC CSCN
Length:84
Mass (Da):7,969
Last modified:March 20, 2007 - v1
Checksum:i5BF71575A9142311
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U57638 mRNA. Translation: AAD10192.1.
AF048750 Genomic DNA. Translation: AAD02475.1.
AC079356 Genomic DNA. Translation: AAU44207.1.
AP008211 Genomic DNA. Translation: BAF16361.1.
CM000142 Genomic DNA. Translation: EAZ32627.1.
RefSeqiNP_001054447.1. NM_001060982.1.
UniGeneiOs.74845.

Genome annotation databases

EnsemblPlantsiOS05T0111300-01; OS05T0111300-01; OS05G0111300.
GeneIDi4337596.
KEGGiosa:4337596.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U57638 mRNA. Translation: AAD10192.1 .
AF048750 Genomic DNA. Translation: AAD02475.1 .
AC079356 Genomic DNA. Translation: AAU44207.1 .
AP008211 Genomic DNA. Translation: BAF16361.1 .
CM000142 Genomic DNA. Translation: EAZ32627.1 .
RefSeqi NP_001054447.1. NM_001060982.1.
UniGenei Os.74845.

3D structure databases

ProteinModelPortali A3AZ88.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS05T0111300-01 ; OS05T0111300-01 ; OS05G0111300 .
GeneIDi 4337596.
KEGGi osa:4337596.

Organism-specific databases

Gramenei A3AZ88.

Phylogenomic databases

InParanoidi A3AZ88.
OMAi TEWHSIT.

Gene expression databases

ExpressionAtlasi A3AZ88. baseline.

Family and domain databases

InterProi IPR000347. Metalthion_15p.
[Graphical view ]
Pfami PF01439. Metallothio_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation of a cDNA clone encoding a type 2 metallothionein-like protein from rice embryo."
    Chen P.-W., Chen L.-J.
    Plant Gene Register PGR97-109
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
    Strain: cv. Lomello.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  4. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  5. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  6. "Down-regulation of metallothionein, a reactive oxygen scavenger, by the small GTPase OsRac1 in rice."
    Wong H.L., Sakamoto T., Kawasaki T., Umemura K., Shimamoto K.
    Plant Physiol. 135:1447-1456(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION.
  7. "Molecular analyses of the metallothionein gene family in rice (Oryza sativa L.)."
    Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.
    J. Biochem. Mol. Biol. 39:595-606(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, TISSUE SPECIFICITY.

Entry informationi

Entry nameiMT2C_ORYSJ
AccessioniPrimary (citable) accession number: A3AZ88
Secondary accession number(s): P93433, Q0DLB2, Q65XV5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: March 20, 2007
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Down-regulation by RAC1 during pathogen infection may potentiate ROS which function as signals in resistance response.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Metallothioneins
    Classification of metallothioneins and list of entries
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3