Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A3AZ88 (MT2C_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Metallothionein-like protein 2C
Alternative name(s):
Class I metallothionein-like protein 2C
OsMT-I-2c
OsMT2b
Gene names
Name:MT2C
Synonyms:MTE
Ordered Locus Names:Os05g0111300, LOC_Os05g02070
ORF Names:OsJ_016110, P0016H04.13
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length84 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Metallothioneins have a high content of cysteine residues that bind various heavy metals. Ref.6

Acts as reactive oxygen species (ROS) scavenger in the cytosol. Possesses superoxide- and hydroxyl radical-scavenging activities in vitro. Ref.6

Subcellular location

Cytoplasmcytosol Ref.6.

Tissue specificity

Highly expressed in inflorescences. Expressed in roots and leaves. Ref.6 Ref.7

Induction

Sinergically down-regulated by RAC1 and sphingolipid elicitor. Ref.6

Miscellaneous

Down-regulation by RAC1 during pathogen infection may potentiate ROS which function as signals in resistance response.

Sequence similarities

Belongs to the metallothionein superfamily. Type 15 family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandMetal-binding
Metal-thiolate cluster
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytosol

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8484Metallothionein-like protein 2C
PRO_0000197408

Sequences

Sequence LengthMass (Da)Tools
A3AZ88 [UniParc].

Last modified March 20, 2007. Version 1.
Checksum: 5BF71575A9142311

FASTA847,969
        10         20         30         40         50         60 
MSCCGGNCGC GSGCQCGGGC GGCKMFPDVE ATATTKTFVL AAPSNKASSG GMEMAVESGE 

        70         80 
NGGCGCNTCK CGTSCSGCSC CSCN 

« Hide

References

« Hide 'large scale' references
[1]"Isolation of a cDNA clone encoding a type 2 metallothionein-like protein from rice embryo."
Chen P.-W., Chen L.-J.
Plant Gene Register PGR97-109
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
Strain: cv. Lomello.
[2]"A fine physical map of the rice chromosome 5."
Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J., Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F., Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.
Mol. Genet. Genomics 274:337-345(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[4]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[5]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[6]"Down-regulation of metallothionein, a reactive oxygen scavenger, by the small GTPase OsRac1 in rice."
Wong H.L., Sakamoto T., Kawasaki T., Umemura K., Shimamoto K.
Plant Physiol. 135:1447-1456(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION.
[7]"Molecular analyses of the metallothionein gene family in rice (Oryza sativa L.)."
Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.
J. Biochem. Mol. Biol. 39:595-606(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, TISSUE SPECIFICITY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U57638 mRNA. Translation: AAD10192.1.
AF048750 Genomic DNA. Translation: AAD02475.1.
AC079356 Genomic DNA. Translation: AAU44207.1.
AP008211 Genomic DNA. Translation: BAF16361.1.
CM000142 Genomic DNA. Translation: EAZ32627.1.
RefSeqNP_001054447.1. NM_001060982.1.
UniGeneOs.74845.

3D structure databases

ProteinModelPortalA3AZ88.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS05T0111300-01; OS05T0111300-01; OS05G0111300.
GeneID4337596.
KEGGosa:4337596.

Organism-specific databases

GrameneA3AZ88.

Phylogenomic databases

OMATEWHSIT.

Family and domain databases

InterProIPR000347. Metalthion_15p.
[Graphical view]
PfamPF01439. Metallothio_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMT2C_ORYSJ
AccessionPrimary (citable) accession number: A3AZ88
Secondary accession number(s): P93433, Q0DLB2, Q65XV5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: March 20, 2007
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

Metallothioneins

Classification of metallothioneins and list of entries