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A3AZ88

- MT2C_ORYSJ

UniProt

A3AZ88 - MT2C_ORYSJ

Protein

Metallothionein-like protein 2C

Gene

MT2C

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Metallothioneins have a high content of cysteine residues that bind various heavy metals.1 Publication
    Acts as reactive oxygen species (ROS) scavenger in the cytosol. Possesses superoxide- and hydroxyl radical-scavenging activities in vitro.1 Publication

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    Metal-binding, Metal-thiolate cluster

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Metallothionein-like protein 2C
    Alternative name(s):
    Class I metallothionein-like protein 2C
    OsMT-I-2c
    OsMT2b
    Gene namesi
    Name:MT2C
    Synonyms:MTE
    Ordered Locus Names:Os05g0111300, LOC_Os05g02070
    ORF Names:OsJ_016110, P0016H04.13
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 5

    Organism-specific databases

    GrameneiA3AZ88.

    Subcellular locationi

    Cytoplasmcytosol 1 Publication

    GO - Cellular componenti

    1. cytosol Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 8484Metallothionein-like protein 2CPRO_0000197408Add
    BLAST

    Expressioni

    Tissue specificityi

    Highly expressed in inflorescences. Expressed in roots and leaves.2 Publications

    Inductioni

    Sinergically down-regulated by RAC1 and sphingolipid elicitor.1 Publication

    Structurei

    3D structure databases

    ProteinModelPortaliA3AZ88.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    OMAiTEWHSIT.

    Family and domain databases

    InterProiIPR000347. Metalthion_15p.
    [Graphical view]
    PfamiPF01439. Metallothio_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A3AZ88-1 [UniParc]FASTAAdd to Basket

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    MSCCGGNCGC GSGCQCGGGC GGCKMFPDVE ATATTKTFVL AAPSNKASSG   50
    GMEMAVESGE NGGCGCNTCK CGTSCSGCSC CSCN 84
    Length:84
    Mass (Da):7,969
    Last modified:March 20, 2007 - v1
    Checksum:i5BF71575A9142311
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U57638 mRNA. Translation: AAD10192.1.
    AF048750 Genomic DNA. Translation: AAD02475.1.
    AC079356 Genomic DNA. Translation: AAU44207.1.
    AP008211 Genomic DNA. Translation: BAF16361.1.
    CM000142 Genomic DNA. Translation: EAZ32627.1.
    RefSeqiNP_001054447.1. NM_001060982.1.
    UniGeneiOs.74845.

    Genome annotation databases

    EnsemblPlantsiOS05T0111300-01; OS05T0111300-01; OS05G0111300.
    GeneIDi4337596.
    KEGGiosa:4337596.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U57638 mRNA. Translation: AAD10192.1 .
    AF048750 Genomic DNA. Translation: AAD02475.1 .
    AC079356 Genomic DNA. Translation: AAU44207.1 .
    AP008211 Genomic DNA. Translation: BAF16361.1 .
    CM000142 Genomic DNA. Translation: EAZ32627.1 .
    RefSeqi NP_001054447.1. NM_001060982.1.
    UniGenei Os.74845.

    3D structure databases

    ProteinModelPortali A3AZ88.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS05T0111300-01 ; OS05T0111300-01 ; OS05G0111300 .
    GeneIDi 4337596.
    KEGGi osa:4337596.

    Organism-specific databases

    Gramenei A3AZ88.

    Phylogenomic databases

    OMAi TEWHSIT.

    Family and domain databases

    InterProi IPR000347. Metalthion_15p.
    [Graphical view ]
    Pfami PF01439. Metallothio_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation of a cDNA clone encoding a type 2 metallothionein-like protein from rice embryo."
      Chen P.-W., Chen L.-J.
      Plant Gene Register PGR97-109
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
      Strain: cv. Lomello.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    4. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    5. "The genomes of Oryza sativa: a history of duplications."
      Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
      , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
      PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    6. "Down-regulation of metallothionein, a reactive oxygen scavenger, by the small GTPase OsRac1 in rice."
      Wong H.L., Sakamoto T., Kawasaki T., Umemura K., Shimamoto K.
      Plant Physiol. 135:1447-1456(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION.
    7. "Molecular analyses of the metallothionein gene family in rice (Oryza sativa L.)."
      Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.
      J. Biochem. Mol. Biol. 39:595-606(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, TISSUE SPECIFICITY.

    Entry informationi

    Entry nameiMT2C_ORYSJ
    AccessioniPrimary (citable) accession number: A3AZ88
    Secondary accession number(s): P93433, Q0DLB2, Q65XV5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 24, 2007
    Last sequence update: March 20, 2007
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Down-regulation by RAC1 during pathogen infection may potentiate ROS which function as signals in resistance response.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Metallothioneins
      Classification of metallothioneins and list of entries
    2. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3