Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A3AF13 (UBP26_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubiquitin carboxyl-terminal hydrolase 26

EC=3.4.19.12
Alternative name(s):
Deubiquitinating enzyme 26
Ubiquitin thioesterase 26
Ubiquitin-specific-processing protease 26
Gene names
Name:UBP26
Ordered Locus Names:Os03g0192800, LOC_Os03g09260
ORF Names:OsJ_009385
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length1079 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Deubiquitinates H2BK143ub1 of histone H2B By similarity.

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the peptidase C19 family.

Contains 3 DUSP domains.

Contains 1 ubiquitin-like domain.

Contains 1 USP domain.

Sequence caution

The sequence ABF94422.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence BAF11157.2 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   Cellular componentNucleus
   DomainRepeat
   Molecular functionHydrolase
Protease
Thiol protease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processubiquitin-dependent protein catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionubiquitin-specific protease activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10791079Ubiquitin carboxyl-terminal hydrolase 26
PRO_0000293494

Regions

Domain106 – 446341USP
Domain495 – 598104DUSP 1
Domain613 – 715103DUSP 2
Domain738 – 862125DUSP 3
Domain961 – 103777Ubiquitin-like

Sites

Active site1151Nucleophile By similarity
Active site3591Proton acceptor By similarity

Sequences

Sequence LengthMass (Da)Tools
A3AF13 [UniParc].

Last modified July 10, 2007. Version 2.
Checksum: 70581F22368079E4

FASTA1,079119,884
        10         20         30         40         50         60 
MSRPNTRNKS KRPRADDCES PSAVFKKIHS TGAITKGDIK QLYMVWKPVC HGCHGNSKDS 

        70         80         90        100        110        120 
PNCFCGLIPA ANGVRKSGLW QRTNEIIRAL GPNPSTDLRD STETPAGLTN LGATCYANSI 

       130        140        150        160        170        180 
LQCLYMNTSF RLGIFSLEPD ILKMHPVLDQ LARLFAQLHS SKMAFIDSAP FIKTLELDNG 

       190        200        210        220        230        240 
VQQDSHEFLT LFLSLLEGSL SHSKVPGART IVQHLFRGSV SHVTRCSSCG RDSEASSKME 

       250        260        270        280        290        300 
DFYELELNIK GLNNLEQSLD DYLSTEALDG ENQYFCESCQ KRVDATRCIK LRSLPPVVNF 

       310        320        330        340        350        360 
QLKRYVFLPK TTTKKKISSA FSFPGQLDMG KRLSNPSSSY TYGLSAILIH KGSAANSGHY 

       370        380        390        400        410        420 
VAHVKDESNG QWWEFDDEHV SKLGLHPFGE KPGKSSDKTD QKPQGSSTAD SVTNDDNNSC 

       430        440        450        460        470        480 
HEAAFTSTME EMFSSTDAYM LMYKRIAKDE NGIESNNISS NNSLPHHFVD EIDERNTSYV 

       490        500        510        520        530        540 
KECEEYESKK DVHLAYITER RQEVKSVLTE APATPEEDSY FWISTDWLRQ WADNVNPPSP 

       550        560        570        580        590        600 
IITGVRVHSS IDNSPIQCEH GKVPASKVTS MKRLSAGAWH KLFSKYGGGP TLSSDDFCME 

       610        620        630        640        650        660 
CLKDGAKNSV SADVYRDRKA SLRSIAEAAL AGNNPDGPLY FVSRPWLTQW LRRKNVDIPS 

       670        680        690        700        710        720 
DADSGPTIAL TCTHGNLLPE HASGAKRVTV PEDLWLFLYE TSGMKIDDIV TFPSDSQPCG 

       730        740        750        760        770        780 
ICSQQLSVVA SVEDNLRAVK LKQRQSHEKL TSGKSLALHP GQKYYLVPSS WLSEWRAYIT 

       790        800        810        820        830        840 
ATGKNISSLP EPQSLEVTIN SLICEKHSRL LQRPLDLVCK RGTITQKASN TDGLTMISES 

       850        860        870        880        890        900 
DWILFSEEWN VAHGKGLCAE IVFSKSSQDN LQSSEAVPIL VEDLDQSTND LSNDLGGREP 

       910        920        930        940        950        960 
YVRTDPEVCE ECIGEKESCA LVEKLNYQNE DIQVYLVRGK EAPKSIREAS AAVPVPDRRT 

       970        980        990       1000       1010       1020 
SKRSRRTTSG NSISLKVSGS TTVYQLKLMI WESLGIVKEN QELHKGSVEI EDDFATLADK 

      1030       1040       1050       1060       1070 
CIFPGDVLWV KDSEIYENRD IADEISEQKV VVQTEEGFRG TLLTSSASAQ LCQDISFSD 

« Hide

References

« Hide 'large scale' references
[1]"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
The rice chromosome 3 sequencing consortium
Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. expand/collapse author list , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DP000009 Genomic DNA. Translation: ABF94422.1. Sequence problems.
AP008209 Genomic DNA. Translation: BAF11157.2. Sequence problems.
CM000140 Genomic DNA. No translation available.
RefSeqNP_001049243.2. NM_001055778.1.
UniGeneOs.56967.

3D structure databases

ProteinModelPortalA3AF13.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4331918.
KEGGosa:4331918.

Organism-specific databases

GrameneA3AF13.

Phylogenomic databases

eggNOGCOG5077.
KOK11858.

Family and domain databases

Gene3D3.30.2230.10. 2 hits.
InterProIPR006615. Pept_C19_DUSP.
IPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
IPR028889. UCH/PAN2.
[Graphical view]
PfamPF06337. DUSP. 2 hits.
PF00443. UCH. 1 hit.
[Graphical view]
SMARTSM00695. DUSP. 1 hit.
[Graphical view]
SUPFAMSSF143791. SSF143791. 2 hits.
SSF54236. SSF54236. 1 hit.
PROSITEPS51283. DUSP. 3 hits.
PS50053. UBIQUITIN_2. 1 hit.
PS00972. USP_1. 1 hit.
PS00973. USP_2. 1 hit.
PS50235. USP_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBP26_ORYSJ
AccessionPrimary (citable) accession number: A3AF13
Secondary accession number(s): Q0DUD1, Q10QK5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 10, 2007
Last modified: June 11, 2014
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

Peptidase families

Classification of peptidase families and list of entries