A3A8W6 (P2C22_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative protein phosphatase 2C 22
Short name=OsPP2C22
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os02g0607500, LOC_Os02g39480
ORF Names:	OsJ_007238, OSJNBa0030C08.21

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	581 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.
Sequence caution	The sequence BAD20141.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Domain	Signal
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein dephosphorylation Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Chain	22 – 581	560	Putative protein phosphatase 2C 22		PRO_0000363268
Regions
	Domain	101 – 432	332	PP2C-like
Sites
	Metal binding	138	1	Manganese 1 By similarity
	Metal binding	138	1	Manganese 2 By similarity
	Metal binding	139	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	373	1	Manganese 2 By similarity
	Metal binding	469	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	A3A8W6 [UniParc]. Last modified February 10, 2009. Version 2. Checksum: DE4AF3912555C979	FASTA	581	63,301
	10 20 30 40 50 60 MVISVPLFSS VLLALVVAVP ADFDVGGRLL GVGLCSVRGD PNEHYDPHGD LYLRPFLQLD 70 80 90 100 110 120 SVHQFYSLVF ARKASSAMGA STSTKRPLTS KVTNEGENDR VKYASSAMQG LRMSMQDALA 130 140 150 160 170 180 VELDLDALKS TSFFGVYDGH GGAEVAMYCA KRFHVMLREE ESFLNNLSYA ITSVCSRLDD 190 200 210 220 230 240 ELEAPNVWRA SLYPHRSSES SSESSDCFQF LSTGSCANVW RSSEAVSYKL PSYEGSTACV 250 260 270 280 290 300 VIIRGNQITV GNVGDSRCVL SKNGQAIDLS TDHKPNVPLE RQRILRVGGQ VWREKFPAKD 310 320 330 340 350 360 SGGEIREQWG PYCIEGKLST SRALAGIFLT TISGDFAYKN IVYRPQYQMV THFPDIRVAK 370 380 390 400 410 420 ITGDTEFLVI ASDGICSIQI LIVDLNTFFP FRDHMSSQDV VDFVHEKLNS RRQELCQSLI 430 440 450 460 470 480 NQGKKRECFT EDSQLATNKN IAPNTTTLGE ETLHTTCEKL VENCLESRNN ATAILVQFKP 490 500 510 520 530 540 GADQPIPALP NIQEGSDEVA GGADQPIPVL PNIQQVSDEV AGGTGQPIPV LPDIQEGSDE 550 560 570 580 VAGGAAVAEQ HQHNPEGGGE QQLDLDDALD GEALALLFGQ P

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006438 Genomic DNA. Translation: BAD20141.1. Sequence problems. CM000139 Genomic DNA. No translation available.
3D structure databases
ProteinModelPortal	A3A8W6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os02g39480.1; LOC_Os02g39480.1; LOC_Os02g39480.
KEGG	dosa:Os02t0607500-00.
Organism-specific databases
Gramene	A3A8W6.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233896.
Family and domain databases
Gene3D	3.60.40.10. 3 hits.
InterPro	IPR001932. PP2C-like. IPR000222. PP2C_Mn2_Asp60_BS. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 2 hits. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C22_ORYSJ

Accession

Primary (citable) accession number: A3A8W6
Secondary accession number(s): Q6K1Z0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	March 6, 2013
This is version 39 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program