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A3A8Q4 (P2C18_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 18

Short name=OsPP2C18
EC=3.1.3.16
Gene names
Ordered Locus Names:Os02g0599200, LOC_Os02g38710
ORF Names:OsJ_007176, OSJNBa0038P01.37
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length804 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Sequence caution

The sequence BAD22514.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence BAF09251.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 804804Probable protein phosphatase 2C 18
PRO_0000363264

Regions

Transmembrane19 – 3921Helical; Potential
Domain128 – 429302PP2C-like

Sites

Metal binding1651Manganese 1 By similarity
Metal binding1651Manganese 2 By similarity
Metal binding1661Manganese 1; via carbonyl oxygen By similarity
Metal binding3841Manganese 2 By similarity
Metal binding4251Manganese 2 By similarity

Experimental info

Sequence conflict407 – 4082VE → LK in CM000139. Ref.3

Sequences

Sequence LengthMass (Da)Tools
A3A8Q4 [UniParc].

Last modified February 10, 2009. Version 2.
Checksum: 4965C18EC3B812DC

FASTA80484,982
        10         20         30         40         50         60 
MGPLLERWIS REGRSDGGDA SGPVLFWCVL IIFAVPDAIR SSSLRLGQVA PRLVLFSNFK 

        70         80         90        100        110        120 
AFRSPKFAKI LPGSDLFSPR VLGFRTRVVL LLDVFEVGFA LFCKASSTMG NSLPVESKVT 

       130        140        150        160        170        180 
VEEENDRIKY IVSSMQGLGH KMEDAHAAIL SLDDTTSTSF FGVYDGHGGA EVASYCAKRF 

       190        200        210        220        230        240 
HIELCNHEDY HNDLTNALDN VFFSMDENLQ QSDAWRELVI PRDNGWMYFL KAGVCANFWP 

       250        260        270        280        290        300 
FPQAYTGPAY EGSTACVVVI RGDQMIVGHA GDSRCVLSRQ GGLAIDLSSD HKPRTSESER 

       310        320        330        340        350        360 
ERVQNAGGIS LGVDCEKVME NYVIKEQWIL GYFGESVTIS RSIGDFAFKQ NKDLNREEQM 

       370        380        390        400        410        420 
LICDPDIHTH DITGDMEFLV IASQGLWSCM ESADVVAYIH VRLLEGVELR VICEELVQSG 

       430        440        450        460        470        480 
LASGENTTVI LVQFKPGAFQ FQYELVDPAA FDTAASNVAS TSAGPAGGSD SDTSATSDEG 

       490        500        510        520        530        540 
VDDTATAGTT TTGYEAGSST GPGSGGGSAN AAFDSGGDLA ANLDIATNFG SDDLAANLDI 

       550        560        570        580        590        600 
ATDIDTEDVF TFINSDDTFG INSDEVELDP NFRPKPQVRR AHDGPSPTPS EIEADLNASP 

       610        620        630        640        650        660 
TRYNMRDIFE AFDKVEAELG GFPLQGHDVS STSTNPNTAT DTGSGSRTGD DDVDGAIARA 

       670        680        690        700        710        720 
MAVASSVMTG AGYEVDSTTT NPSAAADTGS YTGDEIKVDD STSGSARGDS GELVNNDTTV 

       730        740        750        760        770        780 
ADNNASGVAD STTVGDEVDP TATVAADDSN TGDKVDPPAI TKATADSNTS GEVDVDATAT 

       790        800 
ATASASAAVA DDEGTAPDDS EGSP 

« Hide

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[3]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[4]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 343-804.
Strain: cv. Nipponbare.
[5]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006457 Genomic DNA. Translation: BAD22514.1. Sequence problems.
AP008208 Genomic DNA. Translation: BAF09251.1. Sequence problems.
CM000139 Genomic DNA. No translation available.
AK119492 mRNA. No translation available.
RefSeqNP_001047337.1. NM_001053872.1.
UniGeneOs.49987.

3D structure databases

ProteinModelPortalA3A8Q4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39947.LOC_Os02g38710.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4329881.
KEGGosa:4329881.

Organism-specific databases

GrameneA3A8Q4.

Phylogenomic databases

eggNOGCOG0631.
OMANNNEPGD.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 2 hits.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 2 hits.
PROSITEPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameP2C18_ORYSJ
AccessionPrimary (citable) accession number: A3A8Q4
Secondary accession number(s): Q6K1T6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations