Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A3A8Q4

- P2C18_ORYSJ

UniProt

A3A8Q4 - P2C18_ORYSJ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable protein phosphatase 2C 18

Gene

Os02g0599200

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi165 – 1651Manganese 1By similarity
Metal bindingi165 – 1651Manganese 2By similarity
Metal bindingi166 – 1661Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi384 – 3841Manganese 2By similarity
Metal bindingi425 – 4251Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 18 (EC:3.1.3.16)
Short name:
OsPP2C18
Gene namesi
Ordered Locus Names:Os02g0599200, LOC_Os02g38710
ORF Names:OsJ_007176, OSJNBa0038P01.37
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 2

Organism-specific databases

GrameneiA3A8Q4.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 804804Probable protein phosphatase 2C 18PRO_0000363264Add
BLAST

Expressioni

Gene expression databases

ExpressionAtlasiA3A8Q4. baseline.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g38710.1.

Structurei

3D structure databases

ProteinModelPortaliA3A8Q4.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei19 – 3921HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini128 – 429302PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0631.
InParanoidiA3A8Q4.
OMAiNNNEPGD.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3A8Q4 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGPLLERWIS REGRSDGGDA SGPVLFWCVL IIFAVPDAIR SSSLRLGQVA
60 70 80 90 100
PRLVLFSNFK AFRSPKFAKI LPGSDLFSPR VLGFRTRVVL LLDVFEVGFA
110 120 130 140 150
LFCKASSTMG NSLPVESKVT VEEENDRIKY IVSSMQGLGH KMEDAHAAIL
160 170 180 190 200
SLDDTTSTSF FGVYDGHGGA EVASYCAKRF HIELCNHEDY HNDLTNALDN
210 220 230 240 250
VFFSMDENLQ QSDAWRELVI PRDNGWMYFL KAGVCANFWP FPQAYTGPAY
260 270 280 290 300
EGSTACVVVI RGDQMIVGHA GDSRCVLSRQ GGLAIDLSSD HKPRTSESER
310 320 330 340 350
ERVQNAGGIS LGVDCEKVME NYVIKEQWIL GYFGESVTIS RSIGDFAFKQ
360 370 380 390 400
NKDLNREEQM LICDPDIHTH DITGDMEFLV IASQGLWSCM ESADVVAYIH
410 420 430 440 450
VRLLEGVELR VICEELVQSG LASGENTTVI LVQFKPGAFQ FQYELVDPAA
460 470 480 490 500
FDTAASNVAS TSAGPAGGSD SDTSATSDEG VDDTATAGTT TTGYEAGSST
510 520 530 540 550
GPGSGGGSAN AAFDSGGDLA ANLDIATNFG SDDLAANLDI ATDIDTEDVF
560 570 580 590 600
TFINSDDTFG INSDEVELDP NFRPKPQVRR AHDGPSPTPS EIEADLNASP
610 620 630 640 650
TRYNMRDIFE AFDKVEAELG GFPLQGHDVS STSTNPNTAT DTGSGSRTGD
660 670 680 690 700
DDVDGAIARA MAVASSVMTG AGYEVDSTTT NPSAAADTGS YTGDEIKVDD
710 720 730 740 750
STSGSARGDS GELVNNDTTV ADNNASGVAD STTVGDEVDP TATVAADDSN
760 770 780 790 800
TGDKVDPPAI TKATADSNTS GEVDVDATAT ATASASAAVA DDEGTAPDDS

EGSP
Length:804
Mass (Da):84,982
Last modified:February 10, 2009 - v2
Checksum:i4965C18EC3B812DC
GO

Sequence cautioni

The sequence BAD22514.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence BAF09251.1 differs from that shown. Reason: Erroneous gene model prediction.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti407 – 4082VE → LK in CM000139. (PubMed:15685292)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006457 Genomic DNA. Translation: BAD22514.1. Sequence problems.
AP008208 Genomic DNA. Translation: BAF09251.1. Sequence problems.
CM000139 Genomic DNA. No translation available.
AK119492 mRNA. No translation available.
RefSeqiNP_001047337.1. NM_001053872.1.
UniGeneiOs.49987.

Genome annotation databases

GeneIDi4329881.
KEGGiosa:4329881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006457 Genomic DNA. Translation: BAD22514.1 . Sequence problems.
AP008208 Genomic DNA. Translation: BAF09251.1 . Sequence problems.
CM000139 Genomic DNA. No translation available.
AK119492 mRNA. No translation available.
RefSeqi NP_001047337.1. NM_001053872.1.
UniGenei Os.49987.

3D structure databases

ProteinModelPortali A3A8Q4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39947.LOC_Os02g38710.1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4329881.
KEGGi osa:4329881.

Organism-specific databases

Gramenei A3A8Q4.

Phylogenomic databases

eggNOGi COG0631.
InParanoidi A3A8Q4.
OMAi NNNEPGD.

Gene expression databases

ExpressionAtlasi A3A8Q4. baseline.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 2 hits.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 2 hits.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 343-804.
    Strain: cv. Nipponbare.
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C18_ORYSJ
AccessioniPrimary (citable) accession number: A3A8Q4
Secondary accession number(s): Q6K1T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: February 10, 2009
Last modified: October 29, 2014
This is version 53 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3