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A3A8Q4

- P2C18_ORYSJ

UniProt

A3A8Q4 - P2C18_ORYSJ

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Protein

Probable protein phosphatase 2C 18

Gene
Os02g0599200, LOC_Os02g38710, OsJ_007176, OSJNBa0038P01.37
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi165 – 1651Manganese 1 By similarity
Metal bindingi165 – 1651Manganese 2 By similarity
Metal bindingi166 – 1661Manganese 1; via carbonyl oxygen By similarity
Metal bindingi384 – 3841Manganese 2 By similarity
Metal bindingi425 – 4251Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 18 (EC:3.1.3.16)
Short name:
OsPP2C18
Gene namesi
Ordered Locus Names:Os02g0599200, LOC_Os02g38710
ORF Names:OsJ_007176, OSJNBa0038P01.37
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 2

Organism-specific databases

GrameneiA3A8Q4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei19 – 3921Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 804804Probable protein phosphatase 2C 18PRO_0000363264Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g38710.1.

Structurei

3D structure databases

ProteinModelPortaliA3A8Q4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini128 – 429302PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.
Contains 1 PP2C-like domain.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0631.
OMAiNNNEPGD.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3A8Q4-1 [UniParc]FASTAAdd to Basket

« Hide

MGPLLERWIS REGRSDGGDA SGPVLFWCVL IIFAVPDAIR SSSLRLGQVA    50
PRLVLFSNFK AFRSPKFAKI LPGSDLFSPR VLGFRTRVVL LLDVFEVGFA 100
LFCKASSTMG NSLPVESKVT VEEENDRIKY IVSSMQGLGH KMEDAHAAIL 150
SLDDTTSTSF FGVYDGHGGA EVASYCAKRF HIELCNHEDY HNDLTNALDN 200
VFFSMDENLQ QSDAWRELVI PRDNGWMYFL KAGVCANFWP FPQAYTGPAY 250
EGSTACVVVI RGDQMIVGHA GDSRCVLSRQ GGLAIDLSSD HKPRTSESER 300
ERVQNAGGIS LGVDCEKVME NYVIKEQWIL GYFGESVTIS RSIGDFAFKQ 350
NKDLNREEQM LICDPDIHTH DITGDMEFLV IASQGLWSCM ESADVVAYIH 400
VRLLEGVELR VICEELVQSG LASGENTTVI LVQFKPGAFQ FQYELVDPAA 450
FDTAASNVAS TSAGPAGGSD SDTSATSDEG VDDTATAGTT TTGYEAGSST 500
GPGSGGGSAN AAFDSGGDLA ANLDIATNFG SDDLAANLDI ATDIDTEDVF 550
TFINSDDTFG INSDEVELDP NFRPKPQVRR AHDGPSPTPS EIEADLNASP 600
TRYNMRDIFE AFDKVEAELG GFPLQGHDVS STSTNPNTAT DTGSGSRTGD 650
DDVDGAIARA MAVASSVMTG AGYEVDSTTT NPSAAADTGS YTGDEIKVDD 700
STSGSARGDS GELVNNDTTV ADNNASGVAD STTVGDEVDP TATVAADDSN 750
TGDKVDPPAI TKATADSNTS GEVDVDATAT ATASASAAVA DDEGTAPDDS 800
EGSP 804
Length:804
Mass (Da):84,982
Last modified:February 10, 2009 - v2
Checksum:i4965C18EC3B812DC
GO

Sequence cautioni

The sequence BAD22514.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence BAF09251.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti407 – 4082VE → LK in CM000139. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006457 Genomic DNA. Translation: BAD22514.1. Sequence problems.
AP008208 Genomic DNA. Translation: BAF09251.1. Sequence problems.
CM000139 Genomic DNA. No translation available.
AK119492 mRNA. No translation available.
RefSeqiNP_001047337.1. NM_001053872.1.
UniGeneiOs.49987.

Genome annotation databases

GeneIDi4329881.
KEGGiosa:4329881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006457 Genomic DNA. Translation: BAD22514.1 . Sequence problems.
AP008208 Genomic DNA. Translation: BAF09251.1 . Sequence problems.
CM000139 Genomic DNA. No translation available.
AK119492 mRNA. No translation available.
RefSeqi NP_001047337.1. NM_001053872.1.
UniGenei Os.49987.

3D structure databases

ProteinModelPortali A3A8Q4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39947.LOC_Os02g38710.1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4329881.
KEGGi osa:4329881.

Organism-specific databases

Gramenei A3A8Q4.

Phylogenomic databases

eggNOGi COG0631.
OMAi NNNEPGD.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 2 hits.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 2 hits.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 343-804.
    Strain: cv. Nipponbare.
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C18_ORYSJ
AccessioniPrimary (citable) accession number: A3A8Q4
Secondary accession number(s): Q6K1T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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