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Protein

Protein spotted leaf 11

Gene

SPL11

Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Defense related protein that negatively regulates programmed cell death. In vitro, possesses E3 ubiquitin ligase activity.1 Publication

Catalytic activityi

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Recommended name:
Protein spotted leaf 11 (EC:2.3.2.27)
Alternative name(s):
Cell death-related protein SPL11
RING-type E3 ubiquitin transferase SPL11Curated
Gene namesi
Name:SPL11
ORF Names:OsI_037539
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000007015 Componenti: Chromosome 12

Pathology & Biotechi

Disruption phenotypei

Plants exhibit non-race-specific resistance to rice blast fungus (M.grisea) and to bacterial blight (X.oryzae pv oryzae). Lesion mimic mutant spl11 is expressing defense-related genes in fully expanded leaf.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi290V → R: Loss of E3 ubiquitin ligase activity. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003002541 – 694Protein spotted leaf 11Add BLAST694

Proteomic databases

PRIDEiA2ZLU6

Expressioni

Tissue specificityi

Highly expressed in leaf, at intermediate levels in shoot and weakly in root.1 Publication

Inductioni

In both incompatible and compatible interactions with rice blast fungus (M.grisea).

Gene expression databases

ExpressionAtlasiA2ZLU6 differential

Structurei

3D structure databases

ProteinModelPortaliA2ZLU6
SMRiA2ZLU6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini272 – 346U-boxAdd BLAST75
Repeati398 – 438ARM 1Add BLAST41
Repeati439 – 479ARM 2Add BLAST41
Repeati480 – 520ARM 3Add BLAST41
Repeati521 – 561ARM 4Add BLAST41
Repeati562 – 602ARM 5Add BLAST41
Repeati603 – 650ARM 6Add BLAST48

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi7 – 12Poly-Glu6
Compositional biasi18 – 42Ala-richAdd BLAST25
Compositional biasi77 – 84Poly-Glu8

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410ITM3 Eukaryota
ENOG410Y3P9 LUCA

Family and domain databases

Gene3Di1.25.10.10, 2 hits
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR003613 Ubox_domain
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00514 Arm, 3 hits
PF04564 U-box, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 5 hits
SM00504 Ubox, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 1 hit
PS51698 U_BOX, 1 hit

Sequencei

Sequence statusi: Complete.

A2ZLU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGDRAEEEE GEAPPPEARA AAAVERVAAA VEAVAAGAGA GAGEYRNAYR
60 70 80 90 100
RQLLALSRRI RLLGPFVEEL RERRRGEGEG EEEERALAPL ADALEAALAL
110 120 130 140 150
LRLGREGSRI SLVLERDSVM KKFQGVILQL EQALCDIPYN ELDISDEVRE
160 170 180 190 200
QVELVHAQLK RAKERIDMPD DEFYNDLLSV YDKNYDPSAE LAILGRLSEK
210 220 230 240 250
LHLMTITDLT QESLALHEMV ASGGGQDPGE HIERMSMLLK KIKDFVQTQN
260 270 280 290 300
PDMGPPMASR VLDSNGDSRP ITIPDEFRCP ISLELMKDPV IVSTGQTYER
310 320 330 340 350
ACIEKWIASG HHTCPTTQQK MSTSALTPNY VLRSLISQWC ETNGMEPPKR
360 370 380 390 400
STQPNKPTPA CSSSERANID ALLSKLCSPD TEEQRSAAAE LRLLAKRNAN
410 420 430 440 450
NRICIAEAGA IPLLLSLLSS SDLRTQEHAV TALLNLSIHE DNKASIISSG
460 470 480 490 500
AVPSIVHVLK NGSMEARENA AATLFSLSVI DEYKVTIGGM GAIPALVVLL
510 520 530 540 550
GEGSQRGKKD AAAALFNLCI YQGNKGRAIR AGLVPLIMGL VTNPTGALMD
560 570 580 590 600
EAMAILSILS SHPEGKAAIG AAEPVPVLVE MIGSGTPRNR ENAAAVMLHL
610 620 630 640 650
CSGEHHLVHL ARAQECGIMV PLRELALNGT DRGKRKAVQL LERMSRFLVQ
660 670 680 690
QQEEQESQSQ ASAQVPPQAT PEQVPENDIP EQLDSPASQY PMVV
Length:694
Mass (Da):75,300
Last modified:September 11, 2007 - v2
Checksum:i3FEDB892C7289E05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000137 Genomic DNA No translation available.

Genome annotation databases

EnsemblPlantsiOs12t0570000-01; Os12t0570000-01; Os12g0570000
GrameneiOs12t0570000-01; Os12t0570000-01; Os12g0570000

Similar proteinsi

Entry informationi

Entry nameiSL11_ORYSI
AccessioniPrimary (citable) accession number: A2ZLU6
Secondary accession number(s): Q64HA9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: May 23, 2018
This is version 62 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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