A2ZH20 (MT1A_ORYSI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Metallothionein-like protein 1A

Alternative name(s):
Class I metallothionein-like protein 1A
OsMT-I-1a
Short name=OsMT1a

Gene names

Name:	ERR26
Synonyms:	MT-1, MT1A, RGMT-1
ORF Names:	OsI_035863

Organism

Oryza sativa subsp. indica (Rice)

Taxonomic identifier

39946 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	74 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence similarities	Belongs to the metallothionein superfamily. Type 15 family.

Ontologies

Keywords
Ligand	Metal-binding Metal-thiolate cluster
Gene Ontology (GO)
Molecular_function	copper ion binding Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 74	74	Metallothionein-like protein 1A		PRO_0000296353
Experimental info
	Sequence conflict	35	1	V → A in AAB70546. Ref.1
	Sequence conflict	47	1	Q → H in AAB70546. Ref.1
	Sequence conflict	66	1	S → C in AAR85965. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	A2ZH20 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 56E3313EB5D1BE8F	FASTA	74	7,482
	10 20 30 40 50 60 MSCSCGSSCS CGSNCSCGKK YPDLEEKSSS TKATVVLGVA PEKKAQQFEA AAESGETAHG 70 CSCGSSCRCN PCNC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequences of cDNAs encoding three types of metallothionein(MT)-like protein from Oryza sativa L." Kim Y.H., Lee M.C., Yun D.W., Eun M.Y. Plant Gene Register PGR99-019 Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Milyang 23. Tissue: Immature seed.
[2]	"Isolation of rice genes regulated by SA." Yu T., Zhu Y. Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. 93-11.
[3]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. 93-11.
[4]	"A comparative transcriptome map of early and late salinity stress responses in contrasting genotypes of Oryza sativa L." Kumari S., Panjabi V., Singla-Pareek S.L., Sopory S.K., Pareek A. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]	"Molecular analyses of the metallothionein gene family in rice (Oryza sativa L.)." Zhou G., Xu Y., Li J., Yang L., Liu J.-Y. J. Biochem. Mol. Biol. 39:595-606(2006) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF017366 mRNA. Translation: AAB70546.1. AY491534 mRNA. Translation: AAR85965.1. CM000136 Genomic DNA. Translation: EAY81904.1. EF575936 mRNA. Translation: ABR25524.1.
UniGene	Os.3445.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
Gramene	A2ZH20.
Gene expression databases
ArrayExpress	A2ZH20.
Family and domain databases
InterPro	IPR000347. Metalthion_15p. [Graphical view]
Pfam	PF01439. Metallothio_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MT1A_ORYSI

Accession

Primary (citable) accession number: A2ZH20
Secondary accession number(s): O04739 , O22489, Q40633, Q53MA9, Q53NN5, Q53WW8, Q6RUN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	March 20, 2007
Last modified:	April 3, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program