Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Zinc-finger homeodomain protein 1

Gene

ZHD1

Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Putative transcription factor.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei267 – 2671Required for DNA-bindingBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri57 – 10650ZF-HD dimerization-type; degeneratePROSITE-ProRule annotationAdd
BLAST
DNA bindingi215 – 27864HomeoboxAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc-finger homeodomain protein 1
Gene namesi
Name:ZHD1
ORF Names:OsI_31693
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000007015 Componenti: Chromosome 9

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 279279Zinc-finger homeodomain protein 1PRO_0000426036Add
BLAST

Interactioni

Subunit structurei

Homo- and heterodimer with other ZFHD proteins.By similarity

Protein-protein interaction databases

STRINGi39946.BGIOSGA029617-PA.

Structurei

3D structure databases

ProteinModelPortaliA2Z259.
SMRiA2Z259. Positions 216-273.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi152 – 16211Ala-richAdd
BLAST

Domaini

The homeodomain differs form the typical one by having namely 4 instead of 3 extra amino acids inserted in the loop between helix 1 and helix 2.

Sequence similaritiesi

Contains 1 homeobox DNA-binding domain.Curated
Contains 1 ZF-HD dimerization-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri57 – 10650ZF-HD dimerization-type; degeneratePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Homeobox, Zinc-finger

Phylogenomic databases

eggNOGiENOG410IX1N. Eukaryota.
ENOG410YEN7. LUCA.
HOGENOMiHOG000238105.
OMAiMSAMGPL.
OrthoDBiEOG09360PCW.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR006455. Homeodomain_ZF_HD.
IPR006456. ZF_HD_homeobox_Cys/His_dimer.
[Graphical view]
PfamiPF04770. ZF-HD_dimer. 1 hit.
[Graphical view]
ProDomiPD125774. ZF_HD_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF46689. SSF46689. 1 hit.
TIGRFAMsiTIGR01565. homeo_ZF_HD. 1 hit.
TIGR01566. ZF_HD_prot_N. 1 hit.
PROSITEiPS51523. ZF_HD_DIMER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2Z259-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFDDHDDGD EEMPPMPVSS SYETPPQHGL AGGGMAPKPP GEIGSHVKGP
60 70 80 90 100
SCGGGRYREC LKNHAVGIGG HAVDGCGEFM AAGEEGTIDA LRCAACNCHR
110 120 130 140 150
NFHRKESESL AGEGSPFSPA AVVPYGATPH HQFSPYYRTP AGYLHHHQHH
160 170 180 190 200
MAAAAAAAAA AAGGHPQRPL ALPSTSHSGR DDGDDLSGMV GPMSAVGPLS
210 220 230 240 250
GMSLGAGPSG SGSGKKRFRT KFTQEQKDKM LAFAERVGWR IQKHDEAAVQ
260 270
QFCDEVGVKR HVLKVWMHNN KHTLGKKLP
Length:279
Mass (Da):29,496
Last modified:March 20, 2007 - v1
Checksum:i8775D33ADC363DC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000134 Genomic DNA. Translation: EAZ09420.1.

Genome annotation databases

EnsemblPlantsiBGIOSGA029617-TA; BGIOSGA029617-PA; BGIOSGA029617.
GrameneiBGIOSGA029617-TA; BGIOSGA029617-PA; BGIOSGA029617.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000134 Genomic DNA. Translation: EAZ09420.1.

3D structure databases

ProteinModelPortaliA2Z259.
SMRiA2Z259. Positions 216-273.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39946.BGIOSGA029617-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiBGIOSGA029617-TA; BGIOSGA029617-PA; BGIOSGA029617.
GrameneiBGIOSGA029617-TA; BGIOSGA029617-PA; BGIOSGA029617.

Phylogenomic databases

eggNOGiENOG410IX1N. Eukaryota.
ENOG410YEN7. LUCA.
HOGENOMiHOG000238105.
OMAiMSAMGPL.
OrthoDBiEOG09360PCW.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR006455. Homeodomain_ZF_HD.
IPR006456. ZF_HD_homeobox_Cys/His_dimer.
[Graphical view]
PfamiPF04770. ZF-HD_dimer. 1 hit.
[Graphical view]
ProDomiPD125774. ZF_HD_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF46689. SSF46689. 1 hit.
TIGRFAMsiTIGR01565. homeo_ZF_HD. 1 hit.
TIGR01566. ZF_HD_prot_N. 1 hit.
PROSITEiPS51523. ZF_HD_DIMER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZHD1_ORYSI
AccessioniPrimary (citable) accession number: A2Z259
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2014
Last sequence update: March 20, 2007
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.