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Protein

Probable 6-phosphogluconolactonase 2

Gene

OsI_025867

Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.By similarity

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage).
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Glucose-6-phosphate 1-dehydrogenase (OsI_11322), Glucose-6-phosphate 1-dehydrogenase (OsI_07937), Glucose-6-phosphate 1-dehydrogenase (OsI_25709), Glucose-6-phosphate 1-dehydrogenase (OsI_12025)
  2. Probable 6-phosphogluconolactonase 1 (OsI_011697), Probable 6-phosphogluconolactonase 3, chloroplastic (OsI_30141), Probable 6-phosphogluconolactonase 2 (OsI_025867), Probable 6-phosphogluconolactonase 4, chloroplastic (OsI_031067)
  3. 6-phosphogluconate dehydrogenase, decarboxylating (OsI_36123), 6-phosphogluconate dehydrogenase, decarboxylating (OsI_21345)
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 6-phosphogluconolactonase 2 (EC:3.1.1.31)
Short name:
6PGL 2
Gene namesi
ORF Names:OsI_025867
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000007015 Componenti: Chromosome 7

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002886751 – 280Probable 6-phosphogluconolactonase 2Add BLAST280

PTM databases

iPTMnetiA2YNH4.

Interactioni

Protein-protein interaction databases

STRINGi39946.BGIOSGA026090-PA.

Structurei

3D structure databases

ProteinModelPortaliA2YNH4.
SMRiA2YNH4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3147. Eukaryota.
COG0363. LUCA.
HOGENOMiHOG000256285.
OMAiVWFLDKE.
OrthoDBiEOG09360J6V.

Family and domain databases

CDDicd01400. 6PGL. 1 hit.
InterProiView protein in InterPro
IPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
PfamiView protein in Pfam
PF01182. Glucosamine_iso. 1 hit.
TIGRFAMsiTIGR01198. pgl. 1 hit.

Sequencei

Sequence statusi: Complete.

A2YNH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEREISALYE PKRNNEIRIF ESSDEMSTDL AEYISQVSEI SVKERGYFAI
60 70 80 90 100
ALSGGPLVSF LGKLCEAPYN KTLDWSKWYI FWSDERAVAK NHAESNYRIT
110 120 130 140 150
KEGFLSKVPI LNGHVYSIND NATVEDAATD YEFVIRQLVK VRTIGVSESN
160 170 180 190 200
DCPKFDLILL SMGSDGHVAS LFPNHPSLEL KDDWITYITD SPQPPPERIT
210 220 230 240 250
FTLPVINSAS NIAIVTTGDD KSEAVHLAIS DNADGPEAPS SLPARMVQPT
260 270 280
DGKLVWFLDK SAASSLDAEN DDAFEQHREY
Length:280
Mass (Da):31,244
Last modified:March 20, 2007 - v1
Checksum:i4845931408C9A74F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000132 Genomic DNA. Translation: EAZ04635.1.

Genome annotation databases

EnsemblPlantsiBGIOSGA026090-TA; BGIOSGA026090-PA; BGIOSGA026090.
GrameneiBGIOSGA026090-TA; BGIOSGA026090-PA; BGIOSGA026090.

Similar proteinsi

Entry informationi

Entry namei6PGL2_ORYSI
AccessioniPrimary (citable) accession number: A2YNH4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: March 20, 2007
Last modified: August 30, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families