LAC19

Functionⁱ

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityⁱ

4 benzenediol + O₂ = 4 benzosemiquinone + 2 H₂O.

Cofactorⁱ

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature key	Position(s)	Length	Description
Metal bindingⁱ	86 – 86	1	Copper 1By similarity
Metal bindingⁱ	88 – 88	1	Copper 2By similarity
Metal bindingⁱ	131 – 131	1	Copper 2By similarity
Metal bindingⁱ	133 – 133	1	Copper 3By similarity
Metal bindingⁱ	483 – 483	1	Copper 4Sequence analysis
Metal bindingⁱ	486 – 486	1	Copper 1By similarity
Metal bindingⁱ	488 – 488	1	Copper 3By similarity
Metal bindingⁱ	545 – 545	1	Copper 3By similarity
Metal bindingⁱ	546 – 546	1	Copper 4Sequence analysis
Metal bindingⁱ	547 – 547	1	Copper 2By similarity
Metal bindingⁱ	551 – 551	1	Copper 4Sequence analysis
Metal bindingⁱ	556 – 556	1	Copper 4Sequence analysis

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Putative laccase-19 (EC:1.10.3.2) Alternative name(s): Benzenediol:oxygen oxidoreductase 19 Diphenol oxidase 19 Urishiol oxidase 19
Gene namesⁱ	Name:LAC19 ORF Names:OsI_020918
Organismⁱ	Oryza sativa subsp. indica (Rice)
Taxonomic identifierⁱ	39946 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Mesangiospermae › Liliopsida › Petrosaviidae › commelinids › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa
Proteomesⁱ	UP000007015 Componentⁱ: Chromosome 6

Subcellular locationⁱ

Secreted › extracellular space › apoplast Curated

GO - Cellular componentⁱ

apoplast Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Apoplast, Secreted

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Signal peptideⁱ	1 – 28	28	Sequence analysis			Add BLAST
Chainⁱ	29 – 590	562	Putative laccase-19		PRO_0000291904	Add BLAST

Amino acid modifications

Feature key	Position(s)	Length	Description
Glycosylationⁱ	41 – 41	1	N-linked (GlcNAc...)Sequence analysis
Glycosylationⁱ	47 – 47	1	N-linked (GlcNAc...)Sequence analysis
Glycosylationⁱ	120 – 120	1	N-linked (GlcNAc...)Sequence analysis
Glycosylationⁱ	205 – 205	1	N-linked (GlcNAc...)Sequence analysis
Glycosylationⁱ	344 – 344	1	N-linked (GlcNAc...)Sequence analysis
Glycosylationⁱ	378 – 378	1	N-linked (GlcNAc...)Sequence analysis
Glycosylationⁱ	397 – 397	1	N-linked (GlcNAc...)Sequence analysis
Glycosylationⁱ	434 – 434	1	N-linked (GlcNAc...)Sequence analysis
Glycosylationⁱ	465 – 465	1	N-linked (GlcNAc...)Sequence analysis

Keywords - PTMⁱ

Glycoprotein

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	39946.BGIOSGA021910-PA.

STRINGⁱ

39946.BGIOSGA021910-PA.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A2Y9C5.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	Length	Description	Actions
Domainⁱ	36 – 152	117	Plastocyanin-like 1	Add BLAST
Domainⁱ	161 – 315	155	Plastocyanin-like 2	Add BLAST
Domainⁱ	424 – 566	143	Plastocyanin-like 3	Add BLAST

Sequence similaritiesⁱ

Belongs to the multicopper oxidase family.Curated

Contains 3 plastocyanin-like domains.Curated

Keywords - Domainⁱ

Repeat, Signal

Phylogenomic databases

eggNOGⁱ	KOG1263. Eukaryota. COG2132. LUCA.
HOGENOMⁱ	HOG000241916.
OMAⁱ	VSFHHPT.
OrthoDBⁱ	EOG093605N6.

Family and domain databases

Gene3Dⁱ	2.60.40.420. 4 hits.
InterProⁱ	IPR001117. Cu-oxidase. IPR011706. Cu-oxidase_2. IPR011707. Cu-oxidase_3. IPR033138. Cu_oxidase_CS. IPR002355. Cu_oxidase_Cu_BS. IPR008972. Cupredoxin. IPR017761. Laccase. [Graphical view]
Pfamⁱ	PF00394. Cu-oxidase. 1 hit. PF07731. Cu-oxidase_2. 1 hit. PF07732. Cu-oxidase_3. 1 hit. [Graphical view]
SUPFAMⁱ	SSF49503. SSF49503. 4 hits.
TIGRFAMsⁱ	TIGR03389. laccase. 1 hit.
PROSITEⁱ	PS00079. MULTICOPPER_OXIDASE1. 1 hit. PS00080. MULTICOPPER_OXIDASE2. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

A2Y9C5-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEKLSMVTSL LCAITVAVLA VAVVSGEAAV VEHTFVVHEM NATHLCNTTK 
        60         70         80         90        100
IYVVNGQFPG PTVDVMEGDT VVVHVINKLP FGLTIHWHGV RQMRSCWADG 
       110        120        130        140        150
AGFVTECPIP PGNEHTYRFN VTGQVGTLWW HAHVTCLRAT INGAFIVRPR 
       160        170        180        190        200
DGKYPFPTPA KDVPIIIGEW WELDLIELDR RMMDGNFDDN PLSATINGKL 
       210        220        230        240        250
GDLSNCSRMV EESFILDVKH GESYLLRVIN TALFSEYYFR VAGHTFTVVG 
       260        270        280        290        300
ADGNYLTPFK TDMVTVAPGE AIDVIMVADA PPAHYHMIAL ANQPPEPDPQ 
       310        320        330        340        350
IPVFTSRGLV RYAGATANNN GLPVPMPIMP NQHNTMPSYY FHANLTGLAH 
       360        370        380        390        400
PERHRVPMHV DERLFVTLGL GSICRGQNTT CKRRRSPETI VVATMNNVSF 
       410        420        430        440        450
AHPKTTALLE RYYDGTSKGV YTEDFPIRPP RPFNYTNRDL IPPGPLEEAL 
       460        470        480        490        500
EPTFKATKLK RFKYNTSVEI IFQSTTLMQS DSNPMHLHGY DVFLLAQGLG 
       510        520        530        540        550
NFNAKRDVRK FNYHNPQLRN TVQVPRGGWA AIRFVTDNPG MWYLHCHFEF 
       560        570        580        590
HIIMGMATAF IVEDGPTPET SLPPPPPEFK RCGNNGLSQP

Length:590

Mass (Da):65,848

Last modified:March 20, 2007 - v1

Checksum:ⁱ32827189A0F70A37

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CM000131 Genomic DNA. Translation: EAY99685.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

CM000131 Genomic DNA. Translation: EAY99685.1.

Genome annotation databases

EnsemblPlantsⁱ	BGIOSGA021910-TA; BGIOSGA021910-PA; BGIOSGA021910.
Grameneⁱ	BGIOSGA021910-TA; BGIOSGA021910-PA; BGIOSGA021910.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CM000131 Genomic DNA. Translation: EAY99685.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

CM000131 Genomic DNA. Translation: EAY99685.1.

3D structure databases

ProteinModelPortalⁱ	A2Y9C5.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	39946.BGIOSGA021910-PA.

STRINGⁱ

39946.BGIOSGA021910-PA.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblPlantsⁱ	BGIOSGA021910-TA; BGIOSGA021910-PA; BGIOSGA021910.
Grameneⁱ	BGIOSGA021910-TA; BGIOSGA021910-PA; BGIOSGA021910.

Phylogenomic databases

eggNOGⁱ	KOG1263. Eukaryota. COG2132. LUCA.
HOGENOMⁱ	HOG000241916.
OMAⁱ	VSFHHPT.
OrthoDBⁱ	EOG093605N6.

Family and domain databases

Gene3Dⁱ	2.60.40.420. 4 hits.
InterProⁱ	IPR001117. Cu-oxidase. IPR011706. Cu-oxidase_2. IPR011707. Cu-oxidase_3. IPR033138. Cu_oxidase_CS. IPR002355. Cu_oxidase_Cu_BS. IPR008972. Cupredoxin. IPR017761. Laccase. [Graphical view]
Pfamⁱ	PF00394. Cu-oxidase. 1 hit. PF07731. Cu-oxidase_2. 1 hit. PF07732. Cu-oxidase_3. 1 hit. [Graphical view]
SUPFAMⁱ	SSF49503. SSF49503. 4 hits.
TIGRFAMsⁱ	TIGR03389. laccase. 1 hit.
PROSITEⁱ	PS00079. MULTICOPPER_OXIDASE1. 1 hit. PS00080. MULTICOPPER_OXIDASE2. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

LAC19_ORYSI

Accessionⁱ

Primary (citable) accession number: A2Y9C5

Entry historyⁱ

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	March 20, 2007
Last modified:	September 7, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A2Y9C5 (LAC19_ORYSI)

UniProt

A2Y9C5 - LAC19_ORYSI

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Putative laccase-19

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ