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Protein

Cyclin-dependent kinase D-1

Gene

CDKD-1

Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei48ATPPROSITE-ProRule annotation1
Active sitei141Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi25 – 33ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase D-1 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKD;1
Alternative name(s):
CDC2+/CDC28-related protein kinase R2
CDK-activating kinase R2
Short name:
CAK-R2
Gene namesi
Name:CDKD-1
Synonyms:R2
ORF Names:OsI_019159
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000007015 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002961031 – 424Cyclin-dependent kinase D-1Add BLAST424

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei29PhosphothreonineBy similarity1
Modified residuei30PhosphotyrosineBy similarity1
Modified residuei168PhosphoserineBy similarity1
Modified residuei174PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiA2Y4B6

Expressioni

Inductioni

By gibberellic acid (GA3) and submergence.

Gene expression databases

ExpressionAtlasiA2Y4B6 differential

Interactioni

Protein-protein interaction databases

STRINGi39946.BGIOSGA019809-PA

Structurei

3D structure databases

ProteinModelPortaliA2Y4B6
SMRiA2Y4B6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 299Protein kinasePROSITE-ProRule annotationAdd BLAST281

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0659 Eukaryota
ENOG410XQDH LUCA
HOGENOMiHOG000233024
OMAiADIKAWM
OrthoDBiEOG09360B04

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

A2Y4B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGDGGDDA GVKRVADRYL KREVLGEGTY GVVFKADDTK TGNTVAIKKI
60 70 80 90 100
RLGKYKEGVN FTALREIKLL KELKDSNIIE LIDAFPYKGN LHLVFEFMET
110 120 130 140 150
DLEAVIRDRN IVLSPADTKS YIQMMLKGLA FCHKKWVLHR DMKPNNLLIG
160 170 180 190 200
ADGQLKLADF GLARIFGSPE RNFTHQVFAR WYRAPELLFG TKQYGSAVDI
210 220 230 240 250
WAAGCIFAEL LLRRPFLQGS SDIDQLGKIF AAFGTPKSSQ WPDMVYLPDY
260 270 280 290 300
VEYQFVSAPP LRSLFPMASD DALDLLSRMF TYDPKARITA QQALEHRYFL
310 320 330 340 350
SVPAPTKPSQ LPRPPPKGDS GNNKIPDLNL QDGPVVLSPP RKLRRVTAHE
360 370 380 390 400
GMEVHMHRAD RTEEHPSGAR HMDDMSSQSS RIPMSVDVGA IFGTRPAPRP
410 420
TLNSADKSRL KRKLDMDPEF GYTE
Length:424
Mass (Da):47,629
Last modified:March 20, 2007 - v1
Checksum:i735F4B3688D70A4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000130 Genomic DNA Translation: EAY97926.1

Genome annotation databases

EnsemblPlantsiBGIOSGA019809-TA; BGIOSGA019809-PA; BGIOSGA019809
Os05t0392300-02; Os05t0392300-02; Os05g0392300
GrameneiBGIOSGA019809-TA; BGIOSGA019809-PA; BGIOSGA019809
Os05t0392300-02; Os05t0392300-02; Os05g0392300

Similar proteinsi

Entry informationi

Entry nameiCDKD1_ORYSI
AccessioniPrimary (citable) accession number: A2Y4B6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: March 20, 2007
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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