A2XFB7 (PRR73_ORYSI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Two-component response regulator-like PRR73

Alternative name(s):
Pseudo-response regulator 73
Short name=OsPRR73

Gene names

Name:	PRR73
ORF Names:	OsI_010760

Organism

Oryza sativa subsp. indica (Rice)

Taxonomic identifier

39946 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	767 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Controls photoperiodic flowering response. Seems to be one of the component of the circadian clock. Expression of several members of the ARR-like family is controlled by circadian rhythm. The particular coordinated sequential expression of PRR73, PRR37, PRR95, PRR59 and PPR1 result to circadian waves that may be at the basis of the endogenous circadian clock By similarity.
Subcellular location	Nucleus Probable.
Induction	Expressed with a circadian rhythm showing a broad peak in the middle day. Ref.1
Sequence similarities	Belongs to the ARR-like family. Contains 1 CCT domain. Contains 1 response regulatory domain.
Caution	Lacks the phospho-accepting Asp (here Glu-133), present in the receiver domain, which is one of the conserved features of two-component response regulators (ARRs) family.

Ontologies

Keywords
Biological process	Biological rhythms Transcription Transcription regulation Two-component regulatory system
Cellular component	Nucleus
Gene Ontology (GO)
Biological_process	intracellular signal transduction Inferred from electronic annotation. Source: GOC regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW rhythmic process Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	phosphorelay response regulator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 767	767	Two-component response regulator-like PRR73		PRO_0000303008
Regions
	Domain	82 – 200	119	Response regulatory
	Domain	712 – 754	43	CCT
	Compositional bias	238 – 251	14	Asp-rich
Experimental info
	Sequence conflict	33	1	S → P in BAD38859. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	A2XFB7 [UniParc]. Last modified September 11, 2007. Version 2. Checksum: 7E1427881B30CA37	FASTA	767	84,097
	10 20 30 40 50 60 MGSACEAGTD EPSRDDVKGT GNGILENGHS HKSEEEEWRN GMGEDLPNGH STPPEPQQTD 70 80 90 100 110 120 EQKEHQVRIV RWERFLPVKT LRVLLVENDD STRQVVSALL RKCCYEVIPA ENGLHAWQCL 130 140 150 160 170 180 EDLQNHIDLV LTEVVMPRLS GIGLLSKITS HKICKDIPVI MMSSNDSMGT VFKCLSKGAV 190 200 210 220 230 240 DFLVKPIRKN ELKNLWQHVW RRCHSSSGSG SESGIRTQKC TKPKVDDEYE NNSGSNNDNE 250 260 270 280 290 300 DDDDNDEDDD DLSVGHNARD GSDNGSGTQS SWTKRAVEID SPQQMSPDQP SDLPDSTCAQ 310 320 330 340 350 360 VIHPTSEICS NRWLPTANKR SGKKHKENND DSMGKYLEIG APRNSSMEYQ SSPREMSVNP 370 380 390 400 410 420 TEKQHETLMP QSKTTRETDS RNTQNEPTTQ TVDLISSIAR STDDKQVVRI NNAPDCSSKV 430 440 450 460 470 480 PDGNDKNRDS LIDMTSEELG LKRLKTTGSA TEIHDERNIL KRSDLSAFTR YHTTVASNQG 490 500 510 520 530 540 GAGFGGSCSP QDNSSEALKT DSNCKVKSNS DAAEIKQGSN GSSNNNDMGS STKNAITKPS 550 560 570 580 590 600 SNRGKVISPS AVKATQHTSA FHPVQRQTSP ANVVGKDKVD EGIANGVNVG HPVDVQNSFM 610 620 630 640 650 660 QHHHHVHYYV HVMTQQQQQP SIERGSSDAQ CGSSNVFDPP IEGHAANYSV NGSFSGGHNG 670 680 690 700 710 720 NNGQRGPSTA PNVGRPNMET VNGIVDENGA GGGNGSGSGS GNDLYQNGVC YREAALNKFR 730 740 750 760 QKRKVRNFGK KVRYQSRKRL AEQRPRIRGQ FVRQSGQEDQ AGQDEDR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Circadian-associated rice pseudo response regulators (OsPRRs): insight into the control of flowering time." Murakami M., Matsushika A., Ashikari M., Yamashino T., Mizuno T. Biosci. Biotechnol. Biochem. 69:410-414(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION. Strain: cv. Kasalath.
[2]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. 93-11.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB189043 mRNA. Translation: BAD38859.1. CM000128 Genomic DNA. No translation available.
3D structure databases
ProteinModelPortal	A2XFB7.
ModBase	Search...
Protein-protein interaction databases
STRING	39946.BGIOSIBCE010643.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
Gramene	A2XFB7.
Phylogenomic databases
eggNOG	COG0784.
HOGENOM	HOG000034018.
Gene expression databases
ArrayExpress	A2XFB7.
Family and domain databases
InterPro	IPR010402. CCT_domain. IPR011006. CheY-like_superfamily. IPR001789. Sig_transdc_resp-reg_receiver. [Graphical view]
Pfam	PF06203. CCT. 1 hit. PF00072. Response_reg. 1 hit. [Graphical view]
SMART	SM00448. REC. 1 hit. [Graphical view]
SUPFAM	SSF52172. CheY_like. 1 hit.
PROSITE	PS51017. CCT. 1 hit. PS50110. RESPONSE_REGULATORY. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PRR73_ORYSI

Accession

Primary (citable) accession number: A2XFB7
Secondary accession number(s): Q689G4, Q689G7, Q8H8T5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	April 3, 2013
This is version 30 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program